Which antibiotic works best for hidden anal chlamydia?
NCT ID NCT03532464
First seen Apr 24, 2026 · Last updated Jun 22, 2026 · Updated 11 times
Summary
This study compared two common antibiotics—azithromycin (single dose) and doxycycline (7-day course)—for treating anal chlamydia in women who also had a vaginal chlamydia infection. The goal was to see which treatment clears the anal infection better, since anal chlamydia often goes unnoticed and can lead to repeat infections. The trial enrolled 460 women and used a DNA test to check if the infection was gone after treatment.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CHRU Tours
Tours, 37000, France
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CHU de Bordeaux
Bordeaux, 33000, France
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CHU de Nantes
Nantes, 44000, France
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CeGGID - Bordeaux
Bordeaux, 33000, France
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CeGIDD - Marseille
Marseille, Marignane, 13700, France
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Hôpital Hôtel Dieu
Paris, 75004, France
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Hôpital de Roubaix
Roubaix, 59170, France
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
azithromycin and doxycycline
What this could lead to
If this trial succeeds, it could show which antibiotic works better for anorectal chlamydia, helping prevent repeat infections and complications like infertility.
What could go wrong
This is a completed Phase 4 trial, but results may not apply to all populations. Both drugs are already approved, so the benefit is limited to treatment choice rather than a breakthrough.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.