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Friendly bacteria vs. vaginal infections: a new trial puts probiotics to the test

NCT ID NCT06665126

Disease control Sponsor: Happy V Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time

Summary

This virtual trial tests whether a daily prebiotic and probiotic supplement can relieve symptoms of bacterial vaginosis and yeast infections, such as itching, odor, and abnormal discharge. Women aged 25 and older with these concerns will take two capsules daily for 30 days. The study will compare the supplement against placebos and measure changes in the vaginal microbiome and symptom reports.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
A dietary supplement combining prebiotics and probiotics (including Lactobacillus strains and biotin) taken as two capsules daily for 30 days.
What this could lead to
If effective, this supplement could offer a natural, over-the-counter option to help manage symptoms of bacterial vaginosis and yeast infections, potentially reducing reliance on conventional treatments.
What could go wrong
This is an early-stage trial with a modest size, and results may not generalize. The supplement's effects on symptoms and microbiome may be modest, and individual responses can vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

120 people

The number who actually took part.

Started

Oct 2024

Finished

Mar 2025

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

25 years and older

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Women * Age 25+ * Self-reported concerns symptoms associated with bacterial vaginosis or candida overgrowth, including itchiness, redness, abnormal discharge, and an unpleasant odor. * Suffers from digestive issues, including bloating, gas, or other digestive discomfort. * Generally healthy - do not live with any uncontrolled chronic diseases. * Willing to avoid using any vaginal health-related medications, supplements, and herbal remedies for the duration of this study. * If taking oral supplements or herbal remedies targeted at vaginal health, has been consistently taking these for at least 3 months prior to starting the study and is willing to maintain this routine for the study duration. Exclusion Criteria: * Any pre-existing chronic conditions that would prevent participants from adhering to the protocol, including oncological and psychiatric disorders * Planning to undergo any procedure related to their vaginal health. * Started any new medications or supplements that target vaginal health in the past 3 months. * Anyone with known severe allergic reactions that require the use of an Epi-Pen, or any known allergies to any of the product ingredients * Women who are pregnant, breastfeeding, or attempting to conceive * Unwilling to follow the study protocol * Anyone who has undergone any surgeries or invasive treatments in the last three months or has any planned during the study period.

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Conditions

The condition(s) this trial relates to.

bacterial vaginosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bacterial vaginosis Yeast infection

Contacts and locations

Locations

  • Citruslabs

    Santa Monica, California, 90404, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.