Painful endometriosis: could nerve fibers be the culprit?
NCT ID NCT07274956
First seen Jan 06, 2026 · Last updated Jun 19, 2026 · Updated 31 times
Summary
This study looked at 65 women with deep infiltrating endometriosis to see if the number of nerve fibers in their lesions is linked to how much pain they feel. Researchers measured nerve density in surgically removed tissue and compared it to pain scores reported by patients. The goal is to better understand what causes severe pain in endometriosis, which could improve treatment and surgical planning.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Basaksehir Cam Ve Sakura Sehir Hospital
Istanbul, 34060, Turkey (Türkiye)
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Basaksehir Cam ve Sakura City Hospital, Başakşehir Mahallesi G-434 Caddesi No: 2L Başakşehir / İSTANBUL
Istanbul, 34480, Turkey (Türkiye)
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could help doctors better understand why some women with endometriosis have severe pain, potentially leading to more personalized pain management or nerve-sparing surgery.
What could go wrong
This is a small, completed observational study that only looks at existing tissue samples and medical records. It cannot prove that nerve density causes pain, and results may not apply to all patients.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.