Painful endometriosis: could nerve fibers be the culprit?
NCT ID NCT07274956
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 65 women with deep infiltrating endometriosis to see if the number of nerve fibers in their lesions is linked to how much pain they feel. Researchers measured nerve density in surgically removed tissue and compared it to pain scores reported by patients. The goal is to better understand what causes severe pain in endometriosis, which could improve treatment and surgical planning.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this study could help doctors better understand why some women with endometriosis have severe pain, potentially leading to more personalized pain management or nerve-sparing surgery.
- What could go wrong
- This is a small, completed observational study that only looks at existing tissue samples and medical records. It cannot prove that nerve density causes pain, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Basaksehir Cam Ve Sakura Sehir Hospital
Istanbul, 34060, Turkey (Türkiye)
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Basaksehir Cam ve Sakura City Hospital, Başakşehir Mahallesi G-434 Caddesi No: 2L Başakşehir / İSTANBUL
Istanbul, 34480, Turkey (Türkiye)