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Which surgery is safer for a dangerous placenta condition?

NCT ID NCT06861972

Disease control Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time

Summary

This trial compares two surgical strategies for managing placenta accreta, a condition where the placenta grows too deeply into the uterine wall and can cause severe bleeding during delivery. One approach is a caesarean hysterectomy, which removes the uterus after the baby is born. The other is conservative surgery that removes only the affected area of the uterine muscle. The study will look at blood loss, need for transfusions, injuries to nearby organs, and recovery time to see which method may be safer for women with this high-risk pregnancy complication.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Caesarean hysterectomy (removal of the uterus after caesarean delivery) compared with conservative management (removing only the affected part of the uterine muscle).
What this could lead to
If one approach proves safer, it could guide doctors in choosing the best surgical option for women with placenta accreta, potentially reducing severe bleeding and complications.
What could go wrong
This is a small study, and results may not apply to all cases. Both procedures carry risks like heavy bleeding, injury to nearby organs, and the need for blood transfusions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

36 people

The number who actually took part.

Started

Apr 2025

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

A total number of 36 pregnant patients at or after 34 weeks diagnosed of having placenta accreta spectrum were admitted and managed in Kasr Al-Ainy School of Medicine Hospital.

Ages

18 to 40 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Singleton pregnancy with living fetus * Average liquor: 5-25 cm * Gestational age ≥ 34 weeks at time of termination * Previous lower segment cesarean section/s * Suspected placenta accreta spectrum. Exclusion Criteria: * Hepatic, cardio-pulmonary or coagulation disorders * Hemoglobin\< 9.5g/dl * Ruptured membranes * Need for emergency delivery as Antepartum hemorrhage or contractions * Placental abruption * Lower uterine segment fibroids * Consent withdrawal

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Conditions

The condition(s) this trial relates to.

obstetric disorder placenta accreta pregnancy disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Obstetric complication

Contacts and locations

Locations

  • Cairo University Hospitals

    Cairo, 11261, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.