Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Can aspirin uncover hidden vascular differences in endometriosis?

NCT ID NCT05962034

Knowledge-focused Sponsor: Penn State University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time

Summary

This trial investigates whether women with endometriosis have different blood pressure, pain, and platelet responses compared to healthy women. Participants take aspirin or a placebo and undergo handgrip exercise, cold pressor tests, and blood draws. The goal is to understand how blood vessel regulation differs in endometriosis.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
aspirin (acetylsalicylic acid) and placebo
What this could lead to
If differences in vascular regulation are found, this could point toward new ways to manage pain and cardiovascular risk in endometriosis.
What could go wrong
This is a small, early-stage study with only 21 participants, so results may not apply broadly. Aspirin is generally safe but can cause stomach upset or bleeding risk.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

21 people

The number who actually took part.

Started

Jan 2024

Finished

Jul 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Born with a uterus * 18-45 years old * With and without endometriosis Exclusion Criteria: * Currently pregnant or breastfeeding * Diagnosed cardiovascular disease * BMI over 35 * Nicotine use (e.g., smoking, chewing tobacco, vaping, etc.) * Currently using hormone replacement therapy (or have used within previous 6 months) * Known skin allergies or current rash, skin disease, disorders of pigmentation * Diabetes * Renal disease, renal artery stenosis, renal impairment * Liver disease * Stage II Hypertension (blood pressure \>140/\>90 mmHg) * Hypotension (blood pressure \< 90/60 mmHg) * Raynaud's syndrome * Any current medications which could conceivably alter cardiovascular responses (e.g. antihypertension medication, diuretic, digoxin) * Allergy or hypersensitivity to investigational agents * Immunosuppressed/immunocompromised

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Endometriosis are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

endometriosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Endometriosis

Contacts and locations

Locations

  • Noll Laboratory

    University Park, Pennsylvania, 16802, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.