Hidden muscle loss may affect ovarian cancer treatment
NCT ID NCT05415527
First seen Jun 27, 2026 · Last updated Sep 18, 2026 · Updated 2 times
Summary
This study checks for muscle loss (sarcopenia) in 25 women with advanced ovarian cancer before they start chemotherapy. Using CT scans, researchers want to see how common this condition is and if it affects treatment timing. The goal is to better understand how muscle health relates to cancer care.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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25 people
The number who actually took part.
- Started
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Jun 2022
- Finished
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Mar 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age ≥ 18 years. 2. Inoperable, high-grade, epithelial ovarian carcinoma requiring perioperative chemotherapy (neoadjuvant and adjuvant). 3. Optical medical treatment (carboplatin-taxol chemotherapy every 3 weeks) and surgery at Institut Bergonié. 4. Non-clinically undernourished patient, i.e. without loss of more than 10% bodyweight in 6 months 5. Free, informed and written consent signed by the participant and the investigator (on the day of inclusion at the latest and before any tests required for the research). 6. Patient with social security cover in accordance with Article 1121-11 of the French code of public health. Exclusion Criteria: 1. Contraindication to CT-scans. 2. Contraindication to bone mineral densitometry. 3. Patients over the age of 70 the G8 of whom requires oncogeriatric surgery. 4. Patients under guardianship, vulnerable patients or patients under any other legal protection measures. 5. Geographic, social or psychological factors meaning the patient is unable to commit to study follow-up and procedures. 6. Patient already included in this study or in another study evaluating the impact of sarcopenia.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Institut Bergonié
Bordeaux, France
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Other studies related to the condition(s) this trial covers.
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