Could a simple measurement help spot endometriosis earlier?
NCT ID NCT05951452
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at 40 women to see if a physical measurement called anogenital distance (AGD) and certain hormone levels differ between those with and without endometriosis. Researchers measured AGD and took blood and saliva samples before and after showing an empathy-inducing video. The goal was to better understand how endometriosis develops, not to test a treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this research could help identify early physical markers for endometriosis, potentially leading to earlier diagnosis.
- What could go wrong
- This is a small, completed observational study, not a treatment trial. The findings may not apply to all women with endometriosis and need further validation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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40 people
The number who actually took part.
- Started
-
Jan 2024
- Finished
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Jun 2026
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Women with or without endometriosis
- Ages
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20 to 38 years
- Sex
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Female participants only
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Nulliparous woman * No hormonal contraception for at least 3 months * Regular menstrual cycles (between 26 and 32 days) or proven ovulation (positive urine ovulation test ovulation test or progesterone level \>3 ng/ml in the luteal phase) * Normal BMI (≥ 18,5 and \< 30 kg/m²) Specific criteria (ENDO+ group) : * Stage III or IV endometriosis confirmed by laparoscopy or by laparotomy or MRI * Painful symptoms Specific criteria (ENDO- group) : • Patient without endometriosis confirmed by laparoscopy Exclusion Criteria: * Ovarian stimulation planned within 3 months * Adenomyosis * Use of a copper coil * Polycystic ovary syndrome * Pudendal neuralgia * Episiotomy or lesion of the posterior perineum that may modify AGD * Diabetes or thyroid disease * Chronic liver failure, chronic renal failure, cardiac pathology, autoimmune disease * Autism * Diagnosis and/or treatment for psychiatric illness * Chronic exposure to cocaine, methamphetamine, morphine or ecstasy within 30 days before the inclusion visit * Chronic exposure to Tetrahydrocannabinol (THC) within 7 days prior to inclusion. * Patient on treatment(s) that vary oxytocin (e.g. atosiban), testosterone or GnRH * Pregnant or breast-feeding patient * Patients who have given birth or breastfed within 6 weeks before the inclusion visit * Patient unable to read French * Failure to obtain informed consent * Patient not affiliated with or not benefiting from a national health insurance scheme * Person under legal protection, guardianship or curatorship * Patient participating in other research involving the human person
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CHU de Montpellier
Montpellier, 34295, France
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Other studies related to the condition(s) this trial covers.
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