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Egg freezing may shield fertility from repeat ovarian cyst surgeries

NCT ID NCT03823833

Disease control Sponsor: University Hospital, Lille Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether freezing eggs (oocyte cryopreservation) could help preserve fertility in women with benign ovarian cysts that often come back, like endometriomas. The 82 participants had cysts that required multiple surgeries, which can damage the ovaries. Researchers measured how many mature eggs could be collected and frozen, aiming to offer a fertility preservation option before ovarian function declines.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
oocyte cryopreservation (egg freezing)
What this could lead to
If successful, this could provide a standard way to help women with recurrent ovarian cysts protect their fertility before repeated surgeries damage their ovaries.
What could go wrong
This is a small, completed study with 82 participants, so results may not apply to everyone. Egg freezing does not guarantee future pregnancy, and the procedure carries risks like infection or ovarian hyperstimulation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

82 people

The number who actually took part.

Started

Jul 2021

Finished

Apr 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Young women with benign ovarian tumors and high risk of further infertility due to surgery

Ages

18 to 35 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * women with benign ovarian tumor with high risk of recurrence, i-e, endometrioma, dermoid cysts or mucinous cysts. * women with previous surgery and/or high risk of ovarian damage: bilateral cysts, cyst diameter higher than 5 cms * Having a social insurance * Able to give an informed consent Exclusion Criteria: * Borderline tumors * Undetectable AMH levels * Personal history of thrombo-embolic events * pregnancy

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Conditions

The condition(s) this trial relates to.

dermoid cyst endometriosis mucinous cystadenoma Mucocele ovarian cyst ovarian endometriosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dermoid cyst Endometriosis Mucinous cyst

Contacts and locations

Locations

  • Hop Jeanne de Flandre Chu Lille

    Lille, 59037, France

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