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Could adding an immunotherapy drug to chemo help fight advanced ovarian cancer?

NCT ID NCT03275506

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 27 times

Summary

This study tested whether adding the immunotherapy drug pembrolizumab (Keytruda) to standard chemotherapy before surgery helps shrink advanced ovarian cancer more than chemo alone. About 91 women with stage IV ovarian cancer took part. The goal was to see if the combination allowed surgeons to remove all visible tumors during surgery. While promising, this approach is not a cure, as ongoing treatment is still needed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CHRU Jean Minjoz

    Besançon, 25030, France

  • CHU Saint-Etienne - Pôle de Cancérologie

    Saint-Priest-en-Jarez, 42271, France

  • Centre CARIO-HPCA

    Plérin, 22190, France

  • Centre François Baclesse

    Caen, 14000, France

  • Centre Georges François Leclerc

    Dijon, 21079, France

  • Centre Henri Becquerel

    Rouen, 76038, France

  • Centre Hospitalier Départemental Les Oudairies

    La Roche-sur-Yon, 85925, France

  • Centre Hospitalier Intercommunal de Créteil

    Créteil, 94010, France

  • Centre Hospitalier Régional d'Orléans

    Orléans, 45067, France

  • Centre Hospitalier Universitaire Dupuytren

    Limoges, 87042, France

  • Centre Jean Perrin

    Clermont-Ferrand, 63000, France

  • Centre Léon Bérard

    Lyon, 69373, France

  • Clinique Pasteur

    Toulouse, 31076, France

  • Groupe Hospitalier Diaconesses-Croix Saint Simon

    Paris, 75020, France

  • Hôpital Henri Duffaut

    Avignon, 84000, France

  • Hôpital Privé Jean Mermoz

    Lyon, 69373, France

  • Hôpitaux Universitaires de Strasbourg

    Strasbourg, 67091, France

  • ICO Centre René Gauducheau

    Saint-Herblain, 44805, France

  • Institut Claudius Regaud

    Toulouse, 31059, France

  • Institut Jean Godinot

    Reims, 51056, France

  • Institut Mutualiste Montsouris-Jourdan

    Paris, 75674, France

  • Institut Paoli Calmettes

    Marseille, 13009, France

Conditions

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