Massachusetts General Hospital

This study tested a new, more convenient schedule for radiation therapy given before CAR T-cell treatment. Ten adults with B-cell lymphoma that had returned or not responded to other treatments received radiation once a week for five weeks. The main goal was to see if this weekly…

This early-stage study tested a combination of two drugs, bortezomib and lenalidomide, in 22 adults whose acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) had returned after a stem cell transplant. The main goal was to find the highest dose of this drug pair that co…

This study tested whether adding the drug lenalidomide to a standard three-drug chemotherapy regimen (MEC) could improve outcomes for adults with acute myeloid leukemia (AML) that has returned after treatment or didn't respond to initial therapy. The goal was to see if this combi…

This study tested whether a drug called denosumab could help improve bone strength in women with anorexia nervosa who have low bone density. Thirty participants were randomly assigned to receive either the drug or a placebo for one year. The goal was to see if the drug could incr…

This study tested whether freezing one tumor site (cryoablation) could help the body's immune system work better when combined with immunotherapy drugs (pembrolizumab or avelumab) for people with advanced bladder cancer that has spread. The goal was to see if this combination cou…

This study tested whether a medication called sacubitril/valsartan could prevent heart failure in people with HIV. It involved 39 people with HIV who showed early signs of heart changes on scans but had no symptoms. Participants took either the medication or a placebo for six mon…

This study tested the safety and best dose of a drug called enasidenib, given as a maintenance therapy to prevent cancer from returning. It involved 23 adults with specific genetic types of leukemia or related blood cancers who had just received a stem cell transplant. The main g…

This study tested whether the drug denosumab is safe and effective for protecting bones in people with multiple myeloma who also have severe kidney damage. It involved 55 participants who could not take standard bone-protecting drugs due to their kidney condition. Researchers mea…

This small pilot study tested whether a drug called ibutamoren could reduce fat buildup in the livers of people with nonalcoholic fatty liver disease (NAFLD). Researchers enrolled 12 generally healthy adults with NAFLD to take the drug for 6 months. The main goal was to see if li…

This study tested a special therapy program designed to help people living with HIV quit smoking. The program focused on reducing anxiety and depression, which are common challenges that make quitting harder. Researchers compared this 9-session therapy to standard quit-smoking ad…

This small, early-stage study tested whether a newer, more precise form of proton radiation therapy could be practically combined with standard chemotherapy to treat anal cancer. The main goal was to see if this approach could reduce severe skin side effects compared to older rad…

This study tested whether a specialized clinic could help heart failure patients get the right medications at the right doses. Researchers compared 300 patients who received care through this clinic to similar patients getting usual care. The goal was to see if the clinic approac…

This study tested whether adding a precise form of radiation therapy to standard targeted drug treatment could better control advanced lung cancer. It involved 27 people with stage IV non-small cell lung cancer driven by specific gene mutations who were already responding to thei…

This study tested whether a precise form of radiation therapy using proton beams could stop the growth of tumors that spread to the liver from other cancers. 92 participants with 1-4 liver tumors received 2-3 radiation treatments per week for two weeks. The goal was to control th…

This study tested whether changing the timing of home nutrition feeds from overnight to daytime could improve blood sugar control and sleep quality for people with short bowel syndrome. Twenty patients tried their usual overnight feeding for one week, then switched to daytime fee…

This study followed HIV-positive patients who received organ transplants from HIV-positive deceased donors. Researchers wanted to see if this practice was safe and effective compared to receiving organs from HIV-negative donors. They tracked patient survival, organ function, and …

This study tested a combination of two immunotherapy drugs, ipilimumab and nivolumab, for a serious condition where cancer spreads to the fluid surrounding the brain and spinal cord. It involved 18 adults with this advanced complication from various solid tumors. The goal was to …

This early-stage study tested a new combination of two drugs for people with advanced head and neck cancer that had gotten worse despite previous immunotherapy. The goal was to see if giving an oral drug (decitabine) along with an immune-boosting drug (durvalumab) was safe and co…

This early-phase study tested whether the drug ivosidenib could safely help prevent certain blood cancers from returning after a stem cell transplant. The trial involved 18 adults with specific genetic mutations in their cancer cells who had recently undergone transplant. Researc…

This study tested whether a gentle, non-invasive form of brain stimulation could help people with early Alzheimer's disease. Researchers used a device to deliver a specific electrical frequency to the brain, hoping it would reduce the buildup of harmful proteins linked to memory …

This study tested whether adding a specialized geriatric care program (called GRACE) to standard annual wellness doctor visits could improve care for older adults with multiple, complex health issues. Researchers worked with two primary care clinics to design and pilot this combi…

This study tested whether a video visit with a cancer nurse practitioner a few days after leaving the hospital helps patients with advanced cancer. The goal was to see if this extra support made patients feel more confident managing their health, improved communication with their…

This was a small, early-phase study to see if a powerful combination of chemotherapy drugs (called FOLFIRINOX) followed by radiation and more chemo could be safely given before surgery for stomach and GE junction cancer. The goal was to shrink tumors and control the disease to im…

This pilot study tested a combined transplant from a partially matched family donor. It aimed to treat patients who had both a serious blood disorder (like leukemia) and advanced kidney disease at the same time. The goal was to cure the blood disorder and restore kidney function …

This study tested a new support program for people living with HIV who also use drugs like opioids or stimulants. The program combined a phone app for medication reminders with therapy sessions focused on managing emotions and communication. Researchers wanted to see if this appr…

This small pilot study tested whether providing free e-cigarettes for 4 weeks could help heavy smokers who don't plan to quit reduce their cigarette smoking. Researchers enrolled 15 people who had previously tried to quit and gave them e-cigarettes to use instead of regular cigar…

This study tested whether a drug called tesamorelin could help people with obesity and nonalcoholic fatty liver disease (NAFLD). It involved 51 adults and aimed to see if the treatment could reduce harmful fat and inflammation in the liver. The drug works by boosting a natural ho…

This study tested whether having a skin doctor (dermatologist) see patients hospitalized for cellulitis within 24 hours could improve their care. Researchers compared 246 patients who received standard care alone to those who also got a dermatology consultation. They measured if …

This early-stage study tested the safety of a new combination of drugs for adults whose Ewing's sarcoma or rhabdomyosarcoma had returned or spread after standard chemotherapy. The main goal was to find the highest dose of the drugs olaparib and temozolomide (and sometimes a third…

This study tested whether magnetic brain stimulation (TMS) could help reduce symptoms of obsessive compulsive disorder (OCD). Twenty-six adults with OCD received either real TMS or placebo treatment for six weeks while researchers measured their symptoms. The study also aimed to …

This study tested a counseling program designed to help men who have sex with men (MSM) and who are living with HIV and substance use stay engaged in their HIV care. The program focused on helping participants manage difficult emotions like shame and stigma related to HIV, sexual…

This study tested if combining the oral drug TAS-102 with targeted radiation therapy (SBRT) is safe and effective for controlling colorectal cancer that has spread to the liver. The goal was to find the best dose and see if the drug makes the radiation work better to kill cancer …

This study tested different ways to help people with HIV in South Africa stay on their medication and achieve viral suppression. Researchers tried flexible options like offering incentives, community-based care, and home delivery of medication for people who were struggling with …

This early-stage study aimed to find the safest and most effective dose of the drug regorafenib for adults with advanced blood cancers that have returned or stopped responding to standard treatments. It involved 16 participants with conditions like acute myeloid leukemia. The mai…

This study tested whether a specific probiotic called INF108F could help breastfed infants with a food allergy that causes bloody stools and discomfort. Twenty infants received either the probiotic or a placebo for four weeks. Researchers checked if the probiotic changed the babi…

This study tested whether offering money helps homeless adults quit smoking. All 184 participants received free quit-smoking medication and coaching. Half also received cash payments when tests showed they hadn't smoked, to see if the extra incentive made quitting more successful…

This study tested a precise form of radiation called proton beam therapy for people with liver cancer that could not be removed by surgery. The goal was to see if this targeted approach could destroy cancer cells while causing fewer side effects to healthy tissue than standard ra…

This study tested a new, portable version of a breathing exercise technique called heart rate variability biofeedback (HRVB) for people recovering from substance use disorders. The goal was to see if using a small wearable device to guide breathing in the moment could help people…

This study tested whether adding an oral drug called nilotinib to standard radiation therapy was safe for people with high-risk chordoma, a rare type of bone cancer. The main goal was to find the highest safe dose of nilotinib when given alongside radiation. Researchers hoped the…

This study tested a special near-infrared camera system to help surgeons see blood flow in real-time during minimally invasive lung and esophageal cancer surgeries. The goal was to see if this tool could help surgeons better identify healthy tissue and avoid complications like le…

This small study tested a new, faster type of microscope to take detailed pictures of pigmented skin spots, like moles. Researchers compared images from the experimental device to those from a standard dermatoscope used by skin doctors. The goal was to see if the new technology c…

This study tested whether a new 30-minute rapid test for gonorrhea and chlamydia helps doctors manage patients better than the current standard test. About 100 adults with symptoms of a urinary or cervical infection participated. The main goal was to see if the faster test led to…

This study tested whether actively involving fathers during pregnancy and their baby's first year could help prevent rapid weight gain and obesity in infants. Researchers enrolled 657 mother-father pairs from minority backgrounds and randomly assigned them to receive either stand…

This program aimed to prevent obesity by helping mothers and their young children develop healthy habits. It worked with over 1,600 families at community health centers in Boston, focusing on diet, activity, sleep, and social needs like food and housing security. The goal was to …

This study tested whether inhaling nitric oxide gas during and after prolonged heart surgery could prevent acute kidney injury, a serious and common complication. It involved 250 adult patients at high risk for kidney problems due to their blood vessel health. Patients were rando…

This study tested two virtual group programs designed to help older adults worried about their memory reduce lifestyle risk factors for dementia. Sixty participants attended eight weekly online sessions covering topics like exercise, sleep, and nutrition. The main goal was to see…

This study tested a combined approach to prevent a common and serious irregular heartbeat that often occurs after heart surgery. Researchers gave a preventive drug (amiodarone) and used a specific surgical technique (posterior pericardiotomy) in 242 patients undergoing coronary a…

This study tested two different HIV prevention programs adapted for African-born women living in the US. It compared a brief, one-on-one skills session with a more in-depth, peer-led group program. The goal was to see which approach was more effective at increasing condom use and…

This study aimed to find the best way to get more people screened for colorectal cancer in community health centers. Researchers mailed two different at-home screening tests (FIT and Cologuard) to over 5,000 patients who were overdue for their check. They compared which test peop…

This study tested a before-school exercise program called BOKS to see if it helped children. Researchers followed 188 kids aged 5-14 in three Massachusetts schools during 2018. They measured changes in the children's weight, quality of life, and thinking skills to see if the prog…

This study tested whether a drug called denosumab could prevent bone loss that often happens after weight loss surgery. Researchers gave the drug or a placebo to 36 older adults who had either gastric bypass or sleeve gastrectomy surgery. The main goal was to see if the drug help…

This small, completed pilot study tested a new 6-week mind-body program called 'Recovering Together' for people who survived a cardiac arrest and their primary caregivers. The goal was to see if the program was practical and acceptable for reducing emotional distress and improvin…

This small pilot study tested a supportive care program combining wearable fitness trackers with coaching to help Black and Hispanic men with prostate cancer increase exercise and manage treatment side effects. The program aimed to improve quality of life for patients undergoing …

This study tested whether a smartphone app that sends reminders to practice emotional coping skills could help reduce suicidal thoughts. It involved 41 adults who were recently hospitalized for suicidal thoughts or attempts. Half received the app with daily prompts to practice sk…

This study tested a new 3-session telehealth program designed to help adults with cystic fibrosis (CF) manage their chronic pain. The program, called PACE CF, teaches mind-body coping skills and was delivered by a member of the patient's CF care team. Researchers aimed to see if …

This study tested whether a specific type of talk therapy could help people with obsessive-compulsive disorder (OCD), anxiety, or depression who struggle with repetitive, unwanted thoughts. The therapy aimed to teach better attention control skills to help people shift away from …

This study tested whether a gentle, non-invasive stimulation of a nerve in the ear could help reduce the intensity of chronic low back pain. Researchers enrolled 70 adults who had experienced back pain for over six months to try this treatment. The goal was to see if this approac…

This study tested if strengthening a specific hand muscle could help people with thumb base arthritis. 160 adults with thumb arthritis who were using a splint participated. Researchers compared pain and hand strength in people who did the special exercise to those who only used t…

This study tested a stress management and resilience-building program for nurses who care for people with HIV in South Africa's public clinics. The program involved group sessions teaching relaxation and coping skills. Researchers wanted to see if the program was practical and ac…

This study tested whether a 4-week pre-surgery program was practical for older adults with esophageal cancer. The program aimed to improve patients' fitness, nutrition, and sleep before their operation to help them recover better. Researchers enrolled 15 patients to see if they c…

This study tested whether the medication atomoxetine (Strattera®) could safely reduce symptoms of inattention, hyperactivity, and impulsivity in children and teenagers with autism. Sixty participants with autism and significant ADHD-like symptoms were randomly assigned to receive…

This study tested two different online stress and symptom management programs for adults with neurofibromatosis (NF1, NF2, or Schwannomatosis). Researchers compared how these live video programs affected participants' quality of life, stress levels, and ability to cope with their…

This study tested whether connecting older adults with depression to a trained peer mentor through video chats and text messages could help reduce their symptoms. Participants, who were 50 or older and from low-income or minority backgrounds, received 8 weeks of support. The main…

This study tested whether adding a palliative care team to standard cancer treatment could improve the experience for patients with acute myeloid leukemia (AML). Palliative care specialists focus on managing symptoms and providing emotional support. The trial involved 160 hospita…

This study tested a new support program for people caring for a family member with dementia at home. The program provided educational materials and resources through home-based primary care practices. Researchers wanted to see if the program was practical to use and acceptable to…

This small, early-stage study tested a new computer-based program designed to help people with mild memory problems. The program combined gentle movement, acupressure, and relaxation techniques. Researchers primarily wanted to see if people could stick with the program and if it …

This study tested whether cooling the skin could make several non-invasive treatments for Neurofibromatosis Type 1 (NF1) skin tumors less painful. Thirteen adults with NF1 received treatments like lasers and injections on paired tumor sites, with one site cooled and the other not…

This small, early-stage study tested a new 6-session group program designed to help female colorectal and anal cancer survivors improve their sexual well-being after treatment. The main goal was to see if the program was practical and acceptable to participants, and to gather the…

This study tested whether a special nurse support program could improve the well-being of people participating in early-stage cancer drug trials. About 50 patients, along with their caregivers and nurses, took part. The program involved monthly check-ins with a research nurse ove…

This study tested whether natural supplements could help children and teenagers (ages 5-17) who struggle with emotional regulation. Researchers compared two supplement combinations—omega-3 fatty acids with inositol versus N-acetylcysteine (NAC)—over six weeks. The trial was condu…

This small study tested whether a mental health program could help people be more physically active after weight loss surgery. Twelve participants who had surgery 6-12 months earlier received a 10-week program of weekly phone calls, a workbook, and a fitness tracker. The main goa…

This study tested whether a special support package could improve the wellbeing of pregnant doctors-in-training and reduce medical errors. 156 participants were randomly assigned to receive either the support package or standard care. The package included a smart bassinet, a wear…

This study tested whether a non-invasive brain stimulation technique could help improve language abilities in people with primary progressive aphasia (PPA), a condition that causes gradual loss of language skills. Ten participants received magnetic pulses to specific brain areas …

This study tested a new support program designed to improve the quality of life for people with cystic fibrosis (CF) and their caregivers. The program involved regular check-ins to identify and address common problems like pain, stress, and emotional distress. It was implemented …

This study tested whether a non-invasive light treatment, called transcranial photobiomodulation, could help reduce core symptoms of autism in adults. Forty-one participants with autism received either the real light treatment or a sham (placebo) version at home over eight weeks.…

This study tested a new program designed to help family caregivers of people with dementia manage their stress. The program combined mindfulness, self-compassion, and practical skills for handling difficult patient behaviors. Researchers enrolled 82 caregivers to see if the progr…

This study tested whether combining traditional acupuncture with a gentle, non-invasive brain stimulation technique (tDCS) could provide better pain relief for people with chronic low back pain. Researchers enrolled 116 adults with long-term back pain to receive different combina…

This study tested a program that teaches relaxation and mindfulness skills to help people manage chronic pain. Researchers wanted to see if adding a fitness tracker to the program made it more helpful. They enrolled 82 adults with long-term pain to try the program and see if it w…

This study tested whether a mindfulness training smartphone app could help reduce stress for people caring for family members with dementia. Researchers compared the mindfulness app to a general wellness app over 12 weeks. The main goal was to see if using the app was practical a…

This study tested a new program designed to help family caregivers of people with Alzheimer's and related dementias. The program taught mindfulness, self-compassion, and practical skills to manage the stress and difficult behaviors that come with caregiving. Researchers worked wi…

This study aimed to find the most effective dose and timing of light therapy to improve sleep for people with Parkinson's disease. Researchers tested bright white light versus dim red light at different times of day with 203 participants over 16 weeks. The goal was to see which a…

This study tested whether a mind-body walking program is a practical option to help adults with long-term muscle and bone pain. Researchers compared the walking program to a general health education course to see if people could stick with it and if it was well-liked. The main go…

This study tested a new virtual reality (VR) system designed to guide people through acupuncture imagery to help manage chronic low back pain. It involved 31 adults with long-term back pain to see if the VR treatment was safe, acceptable, and could reduce pain. The main goals wer…

This small pilot study tested a culturally adapted mindfulness program for older Black adults who experience both chronic pain and early memory concerns. The goal was to see if the program was practical and acceptable to participants, and to prepare for a larger future study. Res…

This study tested whether a smartphone app could help people manage suicidal thoughts after leaving the hospital. 103 adults who had been hospitalized for suicidal thoughts used an app that sent them random, automated reminders to use their personal safety plan or general coping …

This study created and tested a 4-session training program to help medical interpreters who work with cancer patients. The goal was to teach them skills to better handle the stress and emotional challenges of their job. The program was tested with 28 interpreters from three major…

This study tested whether a psychological support program could improve the well-being of people caring for loved ones undergoing a stem cell transplant for cancer. One hundred caregivers were randomly assigned to receive either the support program or usual care. The program invo…

This study tested whether a 12-week group therapy program was practical and helpful for older adults living with HIV. Fifty participants were randomly assigned to either join the therapy groups or receive basic health information. The goal was to see if learning stress management…

This study compared two surgical approaches for treating trigger finger, a condition where a finger gets stuck in a bent position. Researchers followed 60 adults who had either traditional open surgery or a newer ultrasound-guided procedure to see which method led to better daily…

This study tested whether combining a gentle nerve stimulation device with stress reduction training could help reduce migraine pain. Researchers enrolled 193 adults with migraines and some healthy volunteers to compare their brain scans. The goal was to see if this 8-week combin…

This study tested whether a safe, non-invasive light therapy device could help children and teens with ADHD who also have significant autism-related social difficulties. Participants used the device at home for 8 weeks while their progress was monitored through video check-ins. T…

This study tested whether adding medical cannabis to a behavioral support program could help adults with long-term, non-cancer pain reduce their prescription opioid medication. 87 participants who were already taking high doses of opioids for pain were randomly assigned to either…

This study tested whether providing overnight infant care helps new mothers who are in treatment for substance use disorders. For six weeks, about 20-25 mothers received help caring for their babies for three nights a week so they could get more rest. Researchers wanted to see if…

This small pilot study tested two different 8-week virtual group programs designed to help parents of children with learning and attention difficulties. The goal was to see if the programs were practical and acceptable for reducing caregiver stress and improving well-being. Resea…

This study tested whether taking heated yoga classes could help adults with mild to moderate depression feel better. Researchers enrolled 80 people to either participate in twice-weekly hot yoga sessions or wait for treatment while tracking their symptoms. The main goals were to …

This small pilot study tested a culturally adapted mindfulness therapy program for older Black adults living with both chronic pain and depression. The main goal was to see if the program was practical and acceptable to participants, and to gather initial information on whether i…

This study aimed to understand how a person's mind might help control knee osteoarthritis pain. Researchers used brain scans (fMRI) to see how watching videos about acupuncture, compared to real or fake acupuncture, changed brain activity in 125 patients. The goal was to learn mo…

This small pilot study tested a new smartphone app designed to help people living with HIV quit smoking. The app, called SiS-H, combined quitting strategies with support for staying positive and managing HIV care. Researchers compared it to an existing quit-smoking app to see if …

This small pilot study tested whether a new support system could help manage recurrent pain in children with severe neurological disabilities, who often cannot communicate their discomfort. The system involved weekly surveys for parents, feedback reports for the care team, and su…

This study tested whether a new communication guide was helpful and easy to use for patients facing ostomy surgery. It involved 25 people (patients and nurses) to see if better conversations before surgery could reduce patient anxiety and improve quality of life. The main goal wa…

This study analyzed existing medical data from 1,793 people who had a type of heart attack called acute coronary syndrome. The goal was to find common signs or 'predictors' that a patient's heart attack was caused by a specific problem called plaque erosion, rather than a rupture…

This study aimed to understand how the interaction between an acupuncturist and a patient affects pain relief. Researchers scanned the brains of both fibromyalgia patients and their acupuncturists simultaneously during treatment sessions. The goal was to see if their brain activi…

This study measured how well people with multiple myeloma or Waldenstrom's macroglobulinemia respond to COVID-19 vaccines. Researchers tested 146 participants to see if their weakened immune systems could produce protective antibodies after vaccination. The goal was to understand…

This small, completed pilot study aimed to find a better way to predict how prostate cancer will respond to a standard drug. Researchers tested whether analyzing cancer cells found in the blood (instead of using painful biopsies) could show if the drug was working. Forty men with…

This study aimed to find out if a laser treatment or a simple punch biopsy works better to improve thick, raised burn scars. Researchers tested three small areas on each participant's scar: one got the laser, one got tiny tissue punches, and one got no treatment. They compared th…

This study aimed to understand how a low dose of the sedative drug dexmedetomidine relieves pain by looking at brain activity. Researchers gave the drug to 17 healthy volunteers and used MRI brain scans while applying a controlled pain stimulus. The goal was to map how the drug c…

This study aimed to understand why some patients with sleep apnea develop confusion or memory problems after surgery. Researchers followed 32 patients with moderate-to-severe sleep apnea, performing brain scans and memory tests before and after their operations. They also collect…

This study used advanced brain scans to see if the approved MS drug ocrelizumab reduces inflammation in the brain. Researchers scanned 22 patients with multiple sclerosis before and after about a year of standard ocrelizumab treatment. The goal was to understand how the drug work…

This small pilot study tested whether a single dose of the BCG vaccine, commonly used against tuberculosis, could change markers in the blood and spinal fluid related to brain health and the immune system in older adults. It enrolled 20 participants, some with normal thinking and…

This study aimed to see if shining a special near-infrared light on the head could improve brain functions like memory, focus, and mood in healthy adults. Researchers tested 80 volunteers, comparing the light treatment to a placebo. The goal was to gather knowledge about whether …

This study tested a simple add-on device called AIR that gives real-time feedback to birth attendants as they practice newborn resuscitation on a manikin. The goal was to see if this tool helps healthcare workers learn and maintain proper lifesaving breathing techniques faster an…

This study aimed to understand the connection between blood sugar levels and sleep in adults with cystic fibrosis-related diabetes (CFRD). Thirty participants completed a 10-day home study where their glucose, sleep, and daily activity were monitored remotely. The goal was to gat…

This study explored whether a mild, non-invasive brain stimulation technique could help people with Obsessive-Compulsive Disorder (OCD) better learn to reduce unwanted fears. Researchers tested the stimulation at different times during a two-day fear-learning task with 86 partici…

This study aimed to understand if a non-invasive brain stimulation technique called TMS could help people with bipolar disorder better control their emotions. Researchers compared brain scans of 30 healthy people and 30 people with bipolar disorder while they performed emotion-re…

This study aimed to understand how a hormone called kisspeptin affects how the body processes sugar. Sixteen healthy adults received an infusion of kisspeptin and then drank a sugary solution to test their body's response. The goal was to gather basic knowledge about this hormone…

This small pilot study explored whether taking many microscopic skin samples (smaller than a pinhead) causes less scarring than traditional large skin grafts. Researchers studied 8 healthy adults who were already scheduled for tummy tuck surgery, taking tiny biopsies from their e…

This early-stage study tested whether baricitinib, a drug approved for rheumatoid arthritis, can get into the spinal fluid and reduce signs of brain inflammation in people with Alzheimer's disease, ALS, or early memory concerns. Seventeen participants took the pill daily for 24 w…

This study aimed to better understand how Late Onset Tay-Sachs disease progresses over time. Ten patients with the condition visited the hospital twice, six months apart, for tests like brain scans and movement assessments. The goal was to gather detailed information to help desi…

This study explored whether analyzing the social media and text messages of young women in Kenya could help identify their risk for HIV and their prevention needs. Researchers collected six months of message data from 400 women and compared patterns in their communications with s…

This small, completed study explored whether a non-invasive brain stimulation technique called TMS could help people with bipolar disorder regulate their emotions better. Researchers tested 19 participants to see if stimulating specific brain areas improved their performance on e…

This study aimed to understand if firefighters have different lung scan results compared to non-firefighters, and if their job exposures are linked to these findings. Researchers compared lung scans from over 700 current and retired firefighters with over 1,100 similar non-firefi…

This study asked 714 breast cancer survivors about their experiences getting the COVID-19 vaccine. Researchers wanted to understand their choices, side effects, and concerns, especially about swollen lymph nodes. A key worry was whether this swelling could trigger or worsen a pai…

This study followed children and young adults who had proton radiation for brain or spinal cord tumors. Researchers wanted to see how their thinking skills, emotions, and behavior changed over time, and whether they needed special help in school. They collected this information b…

This study aimed to create a new survey tool to measure health in people with Down syndrome. Researchers worked with caregivers, individuals with Down syndrome, and doctors to develop and test the survey. The goal is to better understand health needs and improve care for this com…

This study aimed to see if a special type of PET/CT scan could predict which patients with a deep vein blood clot (DVT) would later develop a painful, long-term leg condition called post-thrombotic syndrome (PTS). Researchers scanned 51 patients shortly after their DVT diagnosis …

This study tested whether a new medication app helps surgery teams work more efficiently and safely. Forty anesthesia clinicians tried the app in simulated surgery scenarios, comparing it to their current methods. The goal was to see if the app reduces errors and improves workflo…

This study tested whether a mild, non-invasive brain stimulation technique could temporarily improve focus, working memory, and impulse control in adults with ADHD. Researchers compared 83 adults with ADHD to healthy volunteers, measuring changes in computer-based thinking tasks.…

This study tested whether a brief, culturally sensitive support program led by a nurse practitioner could help breast cancer survivors who were hesitant to start their recommended hormone therapy. The program involved two individual sessions and follow-up questionnaires over 12 w…