Could a heart drug lift bipolar depression?

NCT ID NCT02481245

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 27 times

Summary

This study tests whether bezafibrate, a drug used for high cholesterol, can safely improve depression in people with bipolar disorder. About 30 adults with bipolar depression will take bezafibrate alongside their usual mood-stabilizing medication for 8 weeks. Researchers will monitor mood changes, side effects, and thinking skills to see if the drug is worth testing in a larger trial.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Dauten Family Center for Bipolar Treatment Innovation at Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.