DEPRESSIVE EPISODE
Clinical trials for DEPRESSIVE EPISODE explained in plain language.
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Could a heart drug lift bipolar depression?
Symptom relief Recruiting nowThis study tests whether bezafibrate, a drug used for high cholesterol, can safely improve depression in people with bipolar disorder. About 30 adults with bipolar depression will take bezafibrate alongside their usual mood-stabilizing medication for 8 weeks. Researchers will mon…
Matched conditions: DEPRESSIVE EPISODE
Phase: PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated May 17, 2026 04:23 UTC
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Brain Scan-Guided therapy could boost depression treatment
Symptom relief Recruiting nowThis study tests whether using a personalized brain scan to guide a non-invasive treatment called iTBS works better than the standard one-size-fits-all approach for people with major depression. 210 adults will receive 6 weeks of iTBS, with half getting the standard target and ha…
Matched conditions: DEPRESSIVE EPISODE
Phase: NA • Sponsor: The Royal Ottawa Mental Health Centre • Aim: Symptom relief
Last updated May 17, 2026 04:15 UTC
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Can a step-by-step plan beat standard depression care?
Symptom relief Recruiting nowThis study looks at three ways to treat moderate depression in adults aged 18-65: usual care from a family doctor, therapy from a psychologist, or a structured step-by-step treatment plan from a doctor. The goal is to see which approach works best. About 171 people will take part…
Matched conditions: DEPRESSIVE EPISODE
Phase: NA • Sponsor: Aalborg University Hospital • Aim: Symptom relief
Last updated May 17, 2026 04:10 UTC
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Can adjusting sleep and light beat depression faster?
Symptom relief Recruiting nowThis study tests whether adding chronotherapy—a combination of sleep deprivation, sleep schedule changes, and light therapy—to standard depression care can relieve symptoms faster than standard care alone. 76 adults starting treatment for a depressive episode will be randomly ass…
Matched conditions: DEPRESSIVE EPISODE
Phase: NA • Sponsor: St. Olavs Hospital • Aim: Symptom relief
Last updated May 14, 2026 12:02 UTC