DEPRESSIVE EPISODE
Clinical trials for DEPRESSIVE EPISODE explained in plain language.
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Can a quick brain zap keep depression away?
Disease control Recruiting nowThis study looks at whether a non-invasive brain stimulation technique called iTBS can help prevent depression from returning. 60 adults who already improved with iTBS will receive maintenance sessions, either once a day for a week or all in one day. The goal is to see which sche…
Matched conditions: DEPRESSIVE EPISODE
Phase: NA • Sponsor: Berthold Langguth, MD, Ph.D. • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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Can sleep deprivation and light therapy beat the blues in just one week?
Symptom relief Recruiting nowThis study tests whether chronotherapy—a combination of staying awake for 34 hours, light therapy, and a fixed sleep schedule—can quickly improve depression symptoms when added to standard care. 76 adults with moderate to severe depression will be randomly assigned to get chronot…
Matched conditions: DEPRESSIVE EPISODE
Phase: NA • Sponsor: St. Olavs Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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Brain Scan-Guided therapy could boost depression recovery
Symptom relief Recruiting nowThis study tests whether using a person's own brain scan to guide a non-invasive treatment called iTBS works better than the standard one-size-fits-all approach. About 210 adults with major depression will receive 6 weeks of iTBS, with the treatment spot chosen either by standard…
Matched conditions: DEPRESSIVE EPISODE
Phase: NA • Sponsor: The Royal Ottawa Mental Health Centre • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Structured treatment plan may boost depression care in GP clinics
Symptom relief Recruiting nowThis study compares three ways to treat moderate depression in adults aged 18-65: usual care from a general practitioner, behavioral therapy from a psychologist, or a structured step-by-step treatment plan from a GP. The goal is to see if the structured plan works better at easin…
Matched conditions: DEPRESSIVE EPISODE
Phase: NA • Sponsor: Aalborg University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Could a heart drug lift bipolar depression?
Symptom relief Recruiting nowThis study tests whether bezafibrate, a drug currently used for high cholesterol, can safely improve depression in people with bipolar disorder. Thirty adults with bipolar I or II who are already on a mood-stabilizing medication will take bezafibrate for 8 weeks. Researchers will…
Matched conditions: DEPRESSIVE EPISODE
Phase: PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC