DEPRESSIVE EPISODE

This study is testing whether using a person's own brain scan to guide magnetic stimulation treatment works better than the standard approach for major depression. Researchers will enroll 210 adults with depression who haven't responded well to medication. Participants will recei…

This study is testing whether adding a medication called bezafibrate to a person's current mood-stabilizing drugs can help reduce symptoms of depression in people with bipolar disorder. It will involve 30 adults over 8 weeks to check if the treatment is safe and shows signs of wo…

This study tests whether a structured, step-by-step treatment plan for depression works better than standard care. 171 adults with moderate depression will receive either standard GP treatment, psychologist therapy, or the structured medication plan for 12 weeks. Researchers will…

This small pilot study is testing if a single ketone drink can improve symptoms for people with schizophrenia or bipolar disorder. Researchers will compare the ketone drink to a similar-tasting carbohydrate drink in 24 participants. The main goal is to see if the drink improves h…

This study is testing whether a set of non-drug treatments called 'chronotherapy' can help people feel better from depression more quickly. Chronotherapy involves carefully timed sleep changes and bright light therapy, aiming to reset the body's internal clock. The researchers wi…