Mind over stomach: could CBT ease gastroparesis symptoms?

NCT ID NCT03531450

Completed Symptom relief Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether cognitive behavioral therapy (CBT) can reduce symptoms of gastroparesis, a condition where the stomach empties slowly, causing nausea, bloating, and pain. Twenty-seven adults with idiopathic gastroparesis received CBT sessions and were assessed before and after with brain scans, stomach tests, and symptom surveys. The goal was to see if changing thought patterns could improve gut symptoms and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Cognitive Behavioral Therapy (CBT)
What this could lead to: If it works, this could offer a drug-free way to manage gastroparesis symptoms and improve quality of life.
What could go wrong: This is a very small pilot study with only 27 people, so results may not apply to everyone. CBT requires time and effort, and not all patients may benefit.

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Conditions

The condition(s) this trial relates to.

gastroparesis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GASTROPARESIS

Contacts and locations

Locations

Massachusetts General Hospital

Boston, Massachusetts, 02114, United States

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Other studies related to the condition(s) this trial covers.