Gene study reveals why diabetes drugs work differently in people

NCT ID NCT01762046

First seen May 07, 2026 ยท Last updated May 07, 2026

Summary

This study looked at how inherited gene variants influence the body's response to two common diabetes medications, metformin and glipizide. Over 1,000 adults at risk for or with type 2 diabetes participated. Researchers measured glucose and insulin levels after taking the drugs to see if genetic differences explained varied responses. The goal was to better understand the biology behind diabetes treatments, not to test a new therapy.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for DIABETES MELLITUS, TYPE 2 are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02116, United States

  • Joslin Diabetes Center

    Boston, Massachusetts, 02116, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

Conditions

Explore the condition pages connected to this study.