Can bringing HIV prevention to communities beat clinic visits?
NCT ID NCT06176859
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two ways to provide HIV prevention pills (PrEP) to young people in South Africa: the usual clinic-based approach versus a community-based model where pills are delivered and monitored outside clinics. Researchers will enroll 2,500 participants aged 16-30 to see which method leads to more people starting and staying on PrEP over 12 months. The goal is to find a safer, more effective way to expand access to HIV prevention.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Pre-exposure prophylaxis (PrEP) for HIV prevention
What this could lead to
If successful, this could make PrEP more accessible and convenient for young people in South Africa, reducing new HIV infections.
What could go wrong
This is a large but early-stage implementation study; results may not apply to other regions or populations. Community-based delivery may face logistical challenges.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Human Sciences Research Council
Durban, KwaZulu-Natal, South Africa