Immune drug shows promise against rare HPV throat tumors
NCT ID NCT02632344
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested the drug pembrolizumab in 21 people with recurrent respiratory papillomatosis (RRP), a rare condition where HPV causes non-cancerous growths in the throat, windpipe, or lungs. The goal was to see if the drug could shrink these growths and reduce the need for frequent surgeries. Researchers measured response using endoscopic scores and standard tumor criteria, while also monitoring side effects.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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NorthShore University HealthSystem
Evanston, Illinois, 60208, United States
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Other studies related to the condition(s) this trial covers.