Immune drug shows promise against rare HPV throat tumors

NCT ID NCT02632344

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested the drug pembrolizumab in 21 people with recurrent respiratory papillomatosis (RRP), a rare condition where HPV causes non-cancerous growths in the throat, windpipe, or lungs. The goal was to see if the drug could shrink these growths and reduce the need for frequent surgeries. Researchers measured response using endoscopic scores and standard tumor criteria, while also monitoring side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

recurrent respiratory papillomatosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • NorthShore University HealthSystem

    Evanston, Illinois, 60208, United States