Gene therapy retreatment shows promise for rare throat tumor condition
NCT ID NCT06538480
First seen Jan 10, 2026 · Last updated May 14, 2026 · Updated 21 times
Summary
This study tests a gene therapy called Zopapogene imadenovec (Zopa) in adults with recurrent respiratory papillomatosis (RRP), a rare condition causing non-cancerous throat tumors that often come back after surgery. The study has two groups: one checks how the virus used in the therapy leaves the body, and the other sees if retreating with Zopa can prevent the need for surgery for a full year. About 30 participants will be enrolled to evaluate safety and effectiveness.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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National Institute of Health
RECRUITINGBethesda, Maryland, 20892, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Cincinnati
RECRUITINGCincinnati, Ohio, 45267, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Winship Cancer Institute, Emory University
RECRUITINGAtlanta, Georgia, 30322, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Conditions
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