Promising drug combo targets rare spine tumor

NCT ID NCT01407198

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tested the safety of combining the drug nilotinib with standard radiation therapy for people with high-risk chordoma, a rare bone tumor. The goal was to find the highest safe dose of nilotinib that could be given alongside radiation without causing severe side effects. Twenty-three participants were enrolled to help determine the best dose for future studies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CHORDOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.