Promising drug combo targets rare spine tumor

NCT ID NCT01407198

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase study tested the safety of combining the drug nilotinib with standard radiation therapy for people with high-risk chordoma, a rare bone tumor. The goal was to find the highest safe dose of nilotinib that could be given alongside radiation without causing severe side effects. Twenty-three participants were enrolled to help determine the best dose for future studies.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chordoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States