Does IV tylenol beat pills for Post-Surgery pain?
NCT ID NCT02216682
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether giving acetaminophen (Tylenol) through an IV works better than taking it as a pill for pain after knee replacement surgery. Researchers measured pain scores and how much extra opioid painkiller patients needed. The goal is to find the best way to manage pain and reduce opioid use.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- acetaminophen
- What this could lead to
- If IV acetaminophen works better, it could reduce the need for stronger painkillers like opioids after surgery.
- What could go wrong
- This is a small, completed study comparing two forms of a common drug. The difference may be small or not meaningful for all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Other studies related to the condition(s) this trial covers.
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