Brain zapping study reveals sex differences in depression stress response

NCT ID NCT04448327

First seen Jan 08, 2026 · Last updated May 16, 2026 · Updated 29 times

Summary

This study looked at how a gentle nerve stimulation technique (tVNS) affects stress-related brain activity and body functions in people with major depression. 62 adults received either real or fake stimulation during brain scans. The goal was to understand sex differences in stress response, not to treat depression.

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Contacts and locations

Locations

  • Massachusetts General Hospital

    Charlestown, Massachusetts, 02129, United States

Conditions

Explore the condition pages connected to this study.