Blood cancer enzyme deficiency explored in new study

NCT ID NCT04902833

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looked at how often people with certain blood cancers or related conditions have an acquired deficiency of an enzyme called pyruvate kinase, which can cause anemia. Researchers took a single blood sample from 18 participants to measure enzyme activity and check for related gene changes. The goal was to better understand this condition, not to test a treatment.

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Conditions

The condition(s) this trial relates to.

acute myeloid leukemia familial hemolytic anemia myelodysplastic syndrome Myelodysplastic Syndromes myelodysplastic/myeloproliferative disease myelodysplastic/myeloproliferative neoplasm myeloid neoplasm Myeloproliferative Disorders myeloproliferative neoplasm non-autoimmune hemolytic anemia pyruvate kinase deficiency of red cells

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Massachusetts General Hospital

    Boston, Massachusetts, 02115, United States