MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASM
Clinical trials for MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASM explained in plain language.
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New hope for blood cancer patients: experimental drug targets leukemia
Disease control Recruiting nowThis study is testing a new drug called BGB-11417 for people with certain blood cancers like acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). The drug works by blocking a protein that helps cancer cells survive. The study will find safe doses and see if the drug …
Matched conditions: MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE1, PHASE2 • Sponsor: BeiGene • Aim: Disease control
Last updated May 17, 2026 01:48 UTC
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New combo aims to boost stem cell transplant success in aggressive blood cancers
Disease control Recruiting nowThis study tests a two-step approach for people with advanced myeloproliferative neoplasms (blood cancers). First, patients receive a chemotherapy drug (decitabine) plus a targeted therapy (ruxolitinib, fedratinib, or pacritinib) to reduce cancer cells. Then, they undergo a donor…
Matched conditions: MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE2 • Sponsor: University of Washington • Aim: Disease control
Last updated May 17, 2026 01:45 UTC
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New combo therapy aims to make bone marrow transplants safer for older blood cancer patients
Disease control Recruiting nowThis study tests whether adding the drug ruxolitinib to standard transplant care can prevent a serious side effect called graft-versus-host disease (GVHD) in older adults with myelofibrosis or related blood cancers. About 50 participants will receive ruxolitinib before, during, a…
Matched conditions: MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated May 17, 2026 01:44 UTC
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New drug cocktail aims to halt deadly blood cancer progression
Disease control Recruiting nowThis study tests whether adding iadademstat to standard ASTX727 therapy improves outcomes for people with advanced myeloproliferative neoplasms (MPNs), a group of blood cancers. About 62 adults with accelerated or blast-phase MPNs will be randomly assigned to receive ASTX727 alon…
Matched conditions: MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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New hope for rare blood cancers: drug combo trial launches
Disease control Recruiting nowThis study tests a new antibody drug (axatilimab) with or without a chemotherapy-like drug (azacitidine) in people with advanced blood cancers like MPN, MPN/MDS overlap, or high-risk CMML. The goal is to find the best dose and see if the combination can shrink or control the canc…
Matched conditions: MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE1, PHASE2 • Sponsor: Uma Borate • Aim: Disease control
Last updated May 15, 2026 11:53 UTC
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New pill shows promise for Hard-to-Treat blood cancers
Disease control Recruiting nowThis study tests a new daily pill, LP-118, in up to 100 people with blood cancers that have come back or not responded to treatment. The main goal is to find the safest dose and see how the drug works in the body. Early results will also hint at whether it can shrink tumors or sl…
Matched conditions: MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE1 • Sponsor: Newave Pharmaceutical Inc • Aim: Disease control
Last updated May 06, 2026 16:03 UTC
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New immune cell therapy takes aim at lingering leukemia
Disease control Recruiting nowThis early-phase study tests a new treatment for adults with acute myeloid leukemia or myelodysplastic syndrome who still have measurable disease after standard therapy. The treatment uses the patient's own blood cells that are specially armed with a bispecific antibody to target…
Matched conditions: MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE1 • Sponsor: University of Virginia • Aim: Disease control
Last updated May 05, 2026 11:57 UTC
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Immune boosting cells show promise in fighting blood cancers after transplant
Disease control Recruiting nowThis study tests whether giving patients personalized natural killer (NK) cells after chemotherapy and a cord blood transplant can help kill remaining cancer cells and reduce complications. It includes 100 adults with various blood cancers like leukemia, lymphoma, or multiple mye…
Matched conditions: MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Apr 29, 2026 15:02 UTC
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Metal detox may boost chemo for blood cancer patients
Symptom relief Recruiting nowThis early-phase study tests whether two metal-removing drugs (edetate calcium disodium and succimer) are safe and can help control acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) when given alongside chemotherapy. About 58 adults with these blood cancers will rece…
Matched conditions: MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated May 17, 2026 01:50 UTC
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Can a simple pill prevent dangerous bleeding in blood cancer?
Symptom relief Recruiting nowThis study tests whether tranexamic acid, a drug that helps blood clots stay in place, can safely reduce bleeding in people with myelodysplastic syndromes (MDS) or acute myeloid leukemia (AML). About 75 adults receiving less-intensive chemotherapy and having low platelet counts w…
Matched conditions: MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE2 • Sponsor: University of Manitoba • Aim: Symptom relief
Last updated May 17, 2026 01:44 UTC
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Telehealth tool aims to ease tough talks for older cancer patients
Knowledge-focused Recruiting nowThis study tests a telehealth program to help older adults (60+) with blood cancers like leukemia talk with their doctors about their care wishes. It aims to reduce anxiety and improve completion of advance directives. About 207 patients and their caregivers will participate remo…
Matched conditions: MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASM
Phase: NA • Sponsor: University of Rochester • Aim: Knowledge-focused
Last updated May 08, 2026 12:01 UTC