Can pressurized oxygen boost stem cell transplants?
NCT ID NCT03964506
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase study tests whether adding hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) to standard stem cell transplant preparation is safe and helps recovery. It involves 24 adults with various blood cancers, such as leukemia and myelofibrosis. The goal is to see if this approach improves engraftment, reduces mouth sores, and lowers infection risk.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- hyperbaric oxygen therapy
- What this could lead to
- If it works, this could improve stem cell transplant recovery and reduce complications like infections and mouth sores.
- What could go wrong
- This is a very early, small pilot study (24 people) focused on safety. It may not show clear benefits, and hyperbaric oxygen could cause side effects like ear pain or oxygen toxicity.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Wilmot Cancer Institute, University of Rochester
RECRUITINGRochester, New York, 14642, United States
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