MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASM
Clinical trials for MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASM explained in plain language.
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Oral combo therapy trial aims to control aggressive blood cancers
Disease control OngoingThis study is testing if a two-drug oral combination works better than a single oral drug to control symptoms and reduce cancer cells in patients with certain aggressive blood cancers, including chronic myelomonocytic leukemia (CMML). It is a Phase 2 trial with 132 participants, …
Matched conditions: MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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New Two-Drug attack on tough blood cancers
Disease control OngoingThis study is testing a two-drug combination for adults with certain advanced blood cancers, including chronic myelomonocytic leukemia (CMML). The goal is to find the safest and most effective dose of a targeted drug (tagraxofusp) that delivers a toxin directly to cancer cells, c…
Matched conditions: MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 24, 2026 12:01 UTC
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New transplant strategy aims to tame blood cancers and reduce rejection
Disease control OngoingThis study is testing a modified stem cell transplant procedure for patients with high-risk blood cancers. The goal is to see if using specific chemotherapy drugs in a timed sequence before and after the transplant can better control the cancer while reducing harmful immune react…
Matched conditions: MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 23, 2026 15:19 UTC
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Scientists test 'Double Hit' combo against tough blood cancers
Disease control OngoingThis study is testing if adding a new drug called veliparib to a standard two-drug chemotherapy works better for people with advanced blood cancers that have spread and are hard to treat. It will compare the two-drug combo with the three-drug combo in about 25 participants to see…
Matched conditions: MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 23, 2026 15:18 UTC
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Vaccinating donors to arm transplant patients against dangerous virus
Prevention OngoingThis study is testing a new approach to prevent a common and dangerous viral infection called CMV in people receiving a stem cell transplant for blood cancer. Researchers are giving a vaccine to the healthy stem cell donors before the transplant. The goal is to see if the donor's…
Matched conditions: MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Prevention
Last updated Mar 25, 2026 14:08 UTC
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Scientists hunt for hidden cause of anemia in blood cancer patients
Knowledge-focused OngoingThis study aims to find out how common a specific enzyme problem is in people with certain blood cancers and unexplained anemia. Researchers will take one blood sample from about 100 participants who have conditions like myelodysplastic syndrome (MDS) or other related disorders. …
Matched conditions: MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASM
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Mar 06, 2026 15:37 UTC