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Proton beam aims to spare healthy tissue after breast cancer surgery

NCT ID NCT01340495

Completed Disease control Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time

Summary

This study tests a precise type of radiation called proton therapy for women who have had a mastectomy for invasive breast cancer. Unlike standard radiation, proton beams stop at the target area, potentially reducing damage to nearby organs like the heart and lungs. The goal is to see if this approach can lower side effects while still effectively treating the chest wall and lymph nodes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
proton radiation therapy
What this could lead to
If successful, this approach could offer a way to deliver radiation after mastectomy with fewer side effects than standard methods.
What could go wrong
This is a small pilot study, so results may not apply broadly. Proton radiation is not yet widely available and may still cause side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast neoplasm invasive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INVASIVE BREAST CANCER

Contacts and locations

Locations

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.