Can poop and blood predict autism? new study searches for early warning signs

NCT ID NCT04271774

Completed Knowledge-focused Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study followed 344 infants with a sibling diagnosed with autism from birth to age three. Researchers collected blood, stool, urine, and saliva samples to find early biological markers that might predict autism. The goal is to better understand how autism develops and eventually find ways to prevent or ease its symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could lead to earlier detection of autism and eventually help develop ways to prevent or reduce autism-related symptoms.
What could go wrong: This is an observational study, not a treatment trial. The biomarkers identified may not reliably predict autism in all children, and any future solutions are years away.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

autism autism spectrum disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AUTISM SPECTRUM DISORDER

Contacts and locations

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Locations

Massachusetts General Hospital for Children

Boston, Massachusetts, 02114, United States
National University of Ireland Galway

Galway, H91 TK33, Ireland
The Azienda Sanitaria Locale Salerno

Salerno, 84124, Italy

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