Autism

This 24-month study tests whether adding umbilical cord stem cells (AdiaVita) to glutathione therapy helps improve autism symptoms in children ages 3-12. About 100 kids will be randomly assigned to get either glutathione alone or glutathione plus stem cell infusions. Parents and …

This study tests a telehealth program called tele-ImPACT for infants aged 6-24 months who have an older sibling with autism, putting them at higher risk for social communication delays or language disorders. The program teaches parents strategies to support their child's communic…

This study will enroll 1,000 adults with both opioid use disorder and a mental health condition. Participants will receive standard medication for opioid use disorder, with some also getting a team-based support program called MISSION. The goal is to see if MISSION helps people s…

This study tests whether a combination of umbilical cord stem cells and glutathione can safely improve autism symptoms in 100 people aged 3 and older. Participants receive either the stem cell product plus glutathione, or a placebo plus glutathione, with the option to switch grou…

This study tests a program called Tunawiri (meaning 'thrive') that adds mental health screening, counseling, and support to regular HIV care for pregnant and postpartum women in Kenya. The goal is to improve depression, anxiety, and HIV treatment success. Nine hundred women will …

This study tests a gamified mobile health app designed to reduce suicide risk in adults with mental disorders after they leave the hospital. Researchers will enroll 640 participants in Shenzhen, China, and use game-like features to encourage treatment adherence and follow-up visi…

This study tests whether propranolol, a common blood pressure medication, can reduce aggression, self-injury, and severe disruptive behaviors in autistic adolescents and adults. Sixty participants will receive either propranolol or a placebo for 12 weeks, with the option to take …

This study aims to find the best way to sequence two parent-led therapies for young children with autism: one focused on social communication and another on disruptive behavior. Researchers will enroll 184 children aged 18-48 months and their caregivers to compare different thera…

This study looks at how well a special intensive therapy called ACQUIRE Therapy works for children with motor problems caused by conditions like cerebral palsy, autism, or brain injury. The therapy involves many hours of play-based exercises each day, often with a cast or splint …

This study tests whether a non-invasive brain stimulation technique called TMS can help people with mental illness quit smoking. Forty daily smokers with psychiatric conditions will receive either TMS or standard care. The goal is to see if TMS is practical and effective in real-…

This study tests whether the Early Start Denver Model (ESDM), a play-based behavioral therapy, helps young autistic children improve language and daily living skills when used in community programs. Researchers will enroll 600 participants, including 300 children aged 1-5, across…

This study compares two common stimulant classes (amphetamine and methylphenidate) and alpha-2 agonists to treat ADHD in 500 children aged 4-17 with autism. The goal is to find which medication works best and reduce the trial-and-error process. Parents and doctors will track symp…

This study is testing whether a portable eye-tracking device can accurately screen 9-month-old infants for autism spectrum disorder (ASD). Over 2,000 babies will watch short videos while cameras track their eye movements. Researchers will then compare these results with standard …

This study is testing whether a simple, non-invasive eye-tracking test can help diagnose autism in young children (ages 24-72 months) born to mothers with HIV in Kenya. Researchers will compare eye-tracking results with standard clinical autism evaluations in 850 children. If the…

This study is testing whether a smartphone app called BlinkLab Dx1 can help doctors diagnose autism in children ages 2 to 11. The app shows videos and sounds, then measures how children react. Parents also answer questions about their child's development. The goal is to see if th…

Researchers at Indiana University are studying whether a short, non-invasive eye-tracking test can help detect autism risk in children aged 12 to 48 months. The test uses a camera to measure eye movements and pupil size while children watch pictures and videos. Results will be co…

This study is testing a new test called the Five Digits Test (FDT) to see if it can measure a person's ability to stop automatic responses—a skill often affected in ADHD and autism. The FDT does not require reading, making it useful for people with different language backgrounds.…

This study is testing a device called SenseToKnow that uses video and a caregiver survey to help detect autism in children aged 16 to 36 months. The goal is to see how accurate the device is compared to a doctor's diagnosis. About 350 children from Duke Health will take part.

This study looks at how sensory sensitivity affects sleep and emotions in autistic children ages 6-10. Researchers will test a simple bedtime routine called Power Down, where caregivers give their child a gentle massage to help them relax before sleep. The goal is to see if this …

This study tests whether a 16-week behavioral therapy called Pivotal Response Treatment (PRT) works better when done at a center or at home for young children with autism who have language delays. Researchers will compare both groups to children receiving usual care. The goal is …

This study tests a 12-week behavioral therapy program delivered via video calls to help autistic youth (ages 4-17) cope with insistence on sameness—difficulty tolerating changes in routine. Parents are trained to support their child during weekly sessions. The goal is to see if t…

This pilot study tests whether esomeprazole (Nexium), a common stomach acid medication, can improve social communication in 25 children with autism aged 2 to 6. Over 12 weeks, kids take the drug daily, and researchers measure changes in social behavior using standard rating scale…

This study tests whether folinic acid (a form of vitamin B9) can reduce irritability and improve behavior in 150 children aged 3 to 6 with autism. Half will get folinic acid, half a placebo, for 9 weeks. Researchers will also check if it helps with communication, sleep, and gut s…

This study tests whether a parent-led online program can improve sleep in autistic children aged 3 to 7 years. About 130 children will be randomly assigned to one of two behavioral sleep programs for 10 weeks. The goal is to see if the structured program reduces insomnia symptoms…

This study tests a program called SKILLS that focuses on common factors across different mental health conditions, rather than treating each disorder separately. About 60 adults with stable psychiatric diagnoses will take part. The goal is to see if this approach reduces symptoms…

This study tests a specially adapted early intervention for young Hispanic autistic children (18-42 months) from low-income families. The program, called CLR-Pathways, is delivered by bilingual coaches in the home and focuses on improving social communication and daily skills. Re…

This study adapts a group therapy program called Regulating Together for children aged 8-12 with autism and intellectual disability who struggle with emotions like irritability and aggression. The therapy uses relaxation, mindfulness, and parent training to help kids regulate the…

This study tests a brief online program called Project Independence for caregivers of autistic youth aged 10 to 14. The program gives practical tools to help kids build daily living skills like dressing or chores. About 70 caregivers will be randomly assigned to the program or an…

This pilot study tests whether a trauma-focused therapy (TF-CBT) adapted for autistic youth is practical and well-received in community mental health centers. About 24 autistic children and their therapists will participate. The goal is to see if the therapy is acceptable and fea…

This study tests a new therapy for young children (ages 2-5) with autism who use few or no words. The therapy involves parents or therapists responding to the child's sounds and gently encouraging more vocalizations. Researchers will see if this approach helps children make more …

This study tests whether guided breathing exercises can help autistic young adults (ages 16-25) manage stress and improve heart rate variability, a measure of how well the body handles stress. Participants will practice two types of slow breathing exercises and report how useful …

This study is testing a behavioral therapy called 'Being Brave' to help reduce anxiety in autistic children aged 3 to 6. The therapy involves 16 weekly sessions with parents and children, using visual aids and practice exercises. Researchers will also look at biological markers t…

This pilot study tests a digital coaching program for autistic young adults aged 18 to 35. The program uses two conversational agents to deliver personalized goal-setting and support based on a proven model called COMPASS. Over 10 weeks, 38 participants will use the app to work o…

This study tests a program called SUPERCEDE, which provides intensive case management to veterans who are at risk for suicide and receive care both from the VA and outside community providers. The goal is to improve care coordination, reduce suicidal thoughts, and improve daily f…

This pilot study tests whether adding ear acupressure (small seeds taped to ear points) to standard nicotine patches or gum can reduce cravings, withdrawal symptoms, and anxiety in psychiatric inpatients who must stop smoking during their hospital stay. Sixty participants will be…

This study tests a 12-month education and health coaching program for parents of children ages 3-7 who were recently diagnosed with autism. The program focuses on lifestyle factors like diet, sleep, and environment. Researchers want to see if this approach helps reduce autism sym…

This study tests two approaches in public schools: a teacher-led program (RUBIES) to reduce challenging behaviors in autistic children, and a leadership strategy (HELM) to help schools keep using effective methods. About 373 teachers and students in grades K-5 will take part. The…

This study tests a Spanish-language program called Unstuck and On Target for children ages 8-11 with autism and/or ADHD. The program helps kids improve skills like planning and flexibility, and supports their caregivers. About 40 families will either join the program right away o…

This study tests a special speech therapy for minimally verbal children who have both autism and childhood apraxia of speech (a motor planning disorder). The therapy uses motor learning principles in a natural play-like setting. Researchers will enroll 20 children to see if this …

This study tests whether a drug called pimavanserin can reduce rigid, repetitive behaviors in people with autism. About 30 adolescents and adults aged 12 to 40 will receive either the drug or a placebo, then switch. The goal is to see if it improves flexibility and reduces compul…

This study tests whether combining two types of exercises—sensory motor training and special stretches—can reduce toe walking and improve foot posture in children with mild autism. Researchers will measure changes in foot position and sensory responses in 36 children. The goal is…

This study tests if a marijuana-based drug (mostly CBD with a little THC) can reduce anxiety in adults with autism. About 108 people aged 18 to 45 will take the drug or a placebo daily for 8 weeks. Researchers will track anxiety, social skills, and repetitive behaviors through we…

This study is testing whether a virtual reality version of a therapy exercise is practical and helpful for adults (ages 18-65) with psychiatric disorders. Participants will try one VR session and answer questions about their experience. The goal is to see if this approach is acce…

This study tests whether diphenhydramine (Benadryl) can help children and teens with autism fall asleep faster and sleep more soundly. Twenty-six participants aged 8 to 17 will receive either Benadryl or a placebo in a crossover design, with sleep measured by brain waves and acti…

This study tests whether suvorexant (Belsomra) can improve sleep in teenagers with autism spectrum disorder. About 26 teens aged 13-17 will receive either the drug or a placebo in a crossover design over 8 weeks. Researchers will measure sleep quality using brain wave recordings …

This study tests whether zolpidem, a sleep medication, can improve sleep in children and teens with autism. About 26 participants aged 8-17 will receive either the drug or a placebo for 8 weeks, then switch. The goal is to see if the drug helps them fall asleep faster and sleep m…

This study tests an AI chatbot called Aurora that guides people through creating a personal life story to improve emotional well-being and identity. It includes healthy adults, adults with mental health conditions in residential care, and older adults aged 65+. The chatbot is not…

This study compares online parent coaching to in-person coaching for improving social communication in toddlers with autism or social communication delays. About 188 children aged 18-33 months will take part. Parents learn techniques to engage their child during play, aiming to i…

This study is testing a type of talk therapy called Emotion Regulation Therapy (ERT) delivered over video for people in New York who struggle with worry, overthinking, or being hard on themselves. The goal is to see if the therapy helps people better manage their emotions and fee…

This study compares two parenting programs for parents of children aged 2-6 with autism spectrum disorder. One is a structured 13-week group program (Incredible Years), the other is a shorter workshop series. The goal is to see if the longer program reduces parent stress and impr…

This study is testing two group programs for autistic middle-schoolers who are fully included in regular classes. One program focuses on organization, planning, and study skills; the other on social skills. 224 teens and their parents will be randomly assigned to one of the two p…

This study tests a new therapy called TUNE In for adults with autism who struggle with social situations. The therapy helps with social motivation, anxiety, and skills. About 40 adults will take part to see if it improves their social functioning.

This study tests whether high-dose vitamin B6 supplements can reduce anxiety and sensory over-reactivity in autistic adults. Researchers will compare a group taking vitamin B6 to a group taking a placebo. The trial involves 40 participants aged 18 to 60 with an autism diagnosis.

This study tests whether a postbiotic dietary supplement called PostbiotiX Comfort® can improve gut and behavioral symptoms in children with autism spectrum disorder (ASD). Researchers will give the supplement daily for one month to 90 children aged 3-8 years. They will measure c…

This study looks at whether Adderall XR can reduce ADHD symptoms in children and teens (ages 8-18) who also have autism. Participants will take the medication or a placebo for 4 weeks and complete brain scans to measure changes in attention, impulsivity, and memory. The goal is t…

This study tests whether a team of a psychologist, speech therapist, and motor therapist can help children aged 2-7 with neurodevelopmental disorders eat more foods and have fewer mealtime struggles. 24 children will be split into two groups: one gets the team therapy, the other …

This study looks at whether playing pickleball twice a week for 8 weeks can improve movement, sleep, mood, and core autism traits in adults aged 18-45 with autism spectrum disorder. Participants are randomly assigned to start pickleball right away or after a delay. The goal is to…

This study tests a technique called Wilbarger Deep Pressure and Proprioceptive Technique (DPPT) in 40 autistic children aged 6-10 who have trouble with motor skills and sleep. The therapy involves gentle brushing, joint compressions, and calming activities for 30-45 minutes, thre…

This pilot study tests a 16-week telehealth program that coaches parents to help their autistic children who struggle with insistence on sameness—like needing things to stay the same or getting upset over changes. Researchers will see if parents can learn the techniques and if ch…

This study looks at how well and how safely a new sleep medication, lemborexant, works for people who have both a mental health condition and trouble sleeping. About 121 adults will take the drug for 8 weeks, and researchers will track changes in their sleep quality and any side …

This study looks at whether watching Netflix or Disney shows in a small group for 90 minutes each week, over 6 weeks, can improve emotional awareness and reduce anxiety and depression. About 70 adults who have been in mental health treatment for at least 6 months will take part. …

This study compares cognitive behavioral therapy (CBT) with online expert coaching to usual care for children aged 6-14 with autism who struggle with anxiety, irritability, or emotional outbursts. About 100 children and 50 therapists will take part. The goal is to see if the coac…

This study tests whether a 6-week virtual magic trick training program can improve social and emotional skills in adolescents with autism. Sixty teens aged 11-18 will learn tricks from a magician and practice presenting them. Researchers will measure changes in social knowledge, …

This pilot study tests whether a combination of two natural compounds, L-theanine and paraxanthine, can temporarily improve attention and self-control in adults with ADHD or autism. About 24 participants will complete thinking tests and brain scans after taking the supplement or …

This study tests whether virtual reality (VR) can help children with autism learn to recognize and understand emotions. Thirty children aged 7 to 10 will either use an Oculus VR headset or traditional methods to practice identifying feelings like joy, anger, and shame. The goal i…

This study tests a multi-sensory therapy called Heal, which uses calming sounds, gentle vibrations, and soft lighting to help detained youth (ages 12-18) manage their emotions before counseling sessions. The goal is to see if this brief, non-verbal intervention improves emotional…

This study tests whether sailing can help people with psychiatric disorders feel better. Forty adults in France will either take sailing lessons or continue their usual care. Researchers will measure changes in quality of life, mental well-being, and self-esteem to see if sailing…

This study tests whether a gentle brain stimulation technique called tDCS, given while doing social learning tasks on a computer, can reduce anxiety and improve social skills in adults with autism. Twenty high-functioning adults will receive both real and fake (sham) stimulation …

This study tests whether training caregivers of young autistic children (18–72 months) in South Africa can improve the child's communication and daily living skills. Non-specialist coaches teach caregivers strategies they can use during everyday activities. The goal is to support…

This study tests a new approach called ENGAGE, where children with disabilities (like autism or cerebral palsy) help set their own therapy goals. About 96 kids aged 5-12 and their therapists will be split into two groups: one using ENGAGE and the other using usual therapy. Resear…

This study tests a mobile team of pain specialists who visit children and young adults (up to age 25) with moderate to severe intellectual disabilities, autism, or multiple disabilities. The team works with families and caregivers to assess and manage pain in the patient's usual …

This study tests a gentle brain stimulation technique called tDCS in 150 teens with autism. The goal is to see if it can improve social skills, thinking, and behavior, and whether extra 'booster' sessions help the effects last longer. Participants will receive multiple sessions o…

This study tests whether a speech therapy that involves parents can improve early social and communication skills in children aged 6 months to 5 years with neurodevelopmental disabilities. One group gets the parent-focused therapy, while the other gets standard speech therapy. Re…

This study tests whether a cannabis oil containing CBD, terpenes, and a small amount of THC can reduce challenging behaviors and social difficulties in children with autism. About 78 children aged 4 to 12 will take either the cannabis oil or a placebo for 2 months, then all may r…

This study tests a 10-week group program called SDARI that uses acting games and activities to help autistic young adults (ages 18-30) feel more connected and improve their social relationships. Half the participants will do SDARI, while the other half does other structured activ…

This Phase 2 trial tests whether cannabidivarin (CBDV), a compound from cannabis, can reduce irritability and repetitive behaviors in children with autism spectrum disorder. About 100 children aged 5 to 18 will receive either CBDV or a placebo daily for several weeks. Researchers…

This study tests a training program for caregivers of adolescents (ages 10-17) with profound autism. The training teaches caregivers how to use picture-based activity schedules to help their child complete tasks on their own. Researchers will see if the training is practical and …

This study in Norway is testing whether nature-based group activities—like outdoor education and therapy—can improve quality of life for 240 children and youth with ADHD, autism, or Tourette's. Participants will take part in 10- to 12-week programs in schools or healthcare settin…

This study tests a remote therapy model called STAR for toddlers with autism. 110 children will be split into two groups: one receiving STAR therapy plus community care, and the other receiving only community care. The goal is to see if STAR improves social and communication skil…

This study follows 450 babies born with serious heart defects to find early signs of developmental delays by 6 months of age. Researchers want to understand why over half of these children face learning, thinking, or behavior challenges later in life. The goal is to identify risk…

This study screens up to 5,000 healthy volunteers and people at risk for psychiatric or neurodevelopmental disorders like autism. Participants undergo interviews, cognitive tests, and other evaluations to see if they qualify for future research studies at NIH. The goal is to buil…

This study aims to learn more about childhood-onset behavioral, psychiatric, and developmental disorders by observing people of all ages who have these conditions, along with their family members. Researchers will collect medical histories, perform psychiatric assessments, and ma…

This study compares two ways to help adults with mental health issues get follow-up care. One group gets usual care after an emergency room visit, while the other uses a new system that books a psychiatrist appointment within 48 hours through their general doctor. Researchers wil…

This study looks at how using single words or short phrases (instead of full sentences) affects language processing and word learning in young children with autism, ages 1 to 4. Researchers will show children screen-based tasks and track their eye movements to see which type of l…

This study looks at how the brain responds to sensory inputs like sight and sound in 200 children and adults, some with neurodevelopmental disorders (NDD) and some without. Participants will have EEG recordings during sensory tasks, complete behavioral tests, and practice percept…

This study explores whether autistic adults have too much 'plasticity' (flexibility) in the part of the brain that controls movement, and if a non-invasive brain stimulation technique called rTMS can reduce that over-plasticity to improve motor function. Researchers will compare …

This study looks at whether a tool called the Decision Helper helps people with mental health conditions take a more active role in choosing their treatment. About 62 adults in Danish outpatient mental health clinics will have their consultations recorded and analyzed. The goal i…

This study is testing a new, quicker way to diagnose autism in toddlers aged 16-30 months who are already flagged as high risk. Researchers will track how many families are referred, agree to join, and complete the process, including a telehealth option. The goal is to see if thi…

This study looks at the mental health of 200 teenagers aged 12 to 16 who attend special educational institutes (ITEPs) in France. Researchers will use psychiatric interviews to find out how many have conditions like depression or anxiety. The goal is to better understand their ne…

This observational study follows up to 2,000 people with Williams syndrome or related chromosome changes, along with their family members. Researchers will track health, development, behavior, and quality of life from childhood through adulthood. They are also building a biobank …

This study compares two strategies for teaching new words to autistic children aged 4 to 10: repeating words (re-study) versus quizzing after labeling (repeated quizzing). Researchers want to see which method helps children learn nouns and adjectives better and whether they can u…

This study aims to learn how sleep changes as children's brains grow, by collecting sleep and development data from healthy children and those with conditions like autism or ADHD. About 244 children ages 6 months to 8 years will have overnight sleep studies, developmental tests, …

This study aims to improve suicide prevention for people who move between healthcare and the criminal-legal system. Researchers will link health records, Medicaid data, and jail booking information to identify individuals at risk and coordinate care. Over 1,000 adults with past p…

This study follows 50 children and adults with Baker Gordon Syndrome, a rare genetic disorder, to track how the condition changes over time. Participants will undergo brain scans, EEGs, and genetic testing, and complete developmental assessments. The goal is to create better tool…

This study tests whether an online training course can teach parents of children with autism (ages 2-5) a therapy technique called Pivotal Response Treatment. Researchers will check if parents learn the technique and if children's communication improves. 44 families will particip…

This study aims to find the best way to train early intervention providers to deliver high-quality services to children under 3 with communication delays or autism. Researchers will compare two training models for a program called Project ImPACT, measuring how well therapists lea…

This study looks at whether sensitivity to rhythm can predict how well autistic toddlers respond to a social-communication therapy. Forty toddlers aged 18-36 months will receive either standard imitation training or a music-enhanced version. Researchers will track eye gaze to see…

This study tests a new training program called EMIT that helps young autistic children learn to imitate others. Imitation is a key skill for learning and social interaction. The program uses play-based exercises to teach children how to copy actions, sounds, and object use. The s…

This study aims to improve how healthcare professionals recognize autism in older adults and to test a psychoeducation program for those diagnosed. Around 120 participants aged 55 and older with an autism diagnosis will take part. The goal is to see if better training for doctors…

This study tests a smartphone app called Footsteps that helps school aides track behaviors of children aged 4-17 with conditions like autism, ADHD, or oppositional defiant disorder. The goal is to see if the app improves how consistently and accurately aides record data, and whet…

This study looks at how autistic people who also have anorexia nervosa differ in brain structure and behavior from autistic people without anorexia. Researchers want to understand if 'masking' (acting non-autistic to fit in) is linked to eating disorder symptoms and brain changes…

This study tests a remote training program for autistic teens and young adults (ages 13-21) and their primary caregiver. The program teaches strategies to improve thinking and daily life skills. The goal is to see if the program is practical and helpful for participants.

This pilot study is testing a program called CRUSH, which is a sexual health curriculum designed specifically for autistic adults aged 18 to 30. The program includes group sessions and one-on-one coaching to teach about relationships and sexual health. The goal is to see if the p…

This study looks at medical records of 1000 children with conditions like autism, epilepsy, and Down syndrome to find common biological patterns. Researchers want to understand what causes these disorders and how children respond to treatments. The goal is to improve diagnosis an…

This study tests an online training program called WE PLAY for Parents, designed to help parents of young children with autism (ages 3-5) encourage more physical activity. About 114 parents will be randomly assigned to take the training right away or wait 3 months. Researchers wi…

This study explores whether playing specially designed sounds through headphones can normalize brain activity in children aged 5-10 with Fragile X Syndrome or autism. The goal is to reduce sensory sensitivity and improve learning. Participants will listen to sounds while their br…

This study looks at when to start a parent coaching program called JASPER Babble for infants who have an older sibling with autism, putting them at higher risk. About 140 babies will join at 6-8 months old and be randomly assigned to start coaching at 9, 12, or 15 months. Researc…

This study uses magnetoencephalography (MEG), a non-invasive brain scan, to compare brain signals in 1,500 children with neurodevelopmental disorders (like epilepsy, autism, ADHD) and healthy children. The goal is to improve diagnosis and understanding of these conditions. No tre…

This study looks at ways to help families show up for their scheduled appointments at clinics for autism and other neurodevelopmental disorders. Researchers will test different types of reminder messages and see if having a patient navigator call high-risk families makes a differ…

This study follows 100 infants and toddlers with either a high or low family risk of autism spectrum disorder (ASD). Researchers will track how prosocial behaviors—like helping and understanding others—develop, along with brain network changes measured by EEG and MRI. The goal is…

This study looks at whether a program with a nurse case manager can help people leaving prison visit a doctor or clinic instead of the emergency room. About 488 adults with a history of substance use and a chronic health condition will take part. Some will get extra support from …

This study aims to identify sensory patterns in autistic individuals from childhood to adulthood. Researchers will use questionnaires and brain imaging (fMRI and EEG) to explore how sensory experiences relate to social challenges like avoiding eye contact or touch. The goal is to…

This study is testing a program that helps teachers and parents work together to support preschoolers who have trouble with social communication. The program is run by preschool staff and uses proven teaching methods. Researchers want to see if the program is easy to use and if f…

This study looks at balance problems in children with autism aged 6 to 10. Using a virtual reality system, researchers will measure how kids stand still and see if balance is linked to thinking skills. The goal is to better understand these challenges, not to test a treatment.

This study looks at how movement and sensory differences in children with autism might serve as early signs of the condition. Researchers will follow 300 participants, including autistic children, their parents, and infants at higher risk, over time. The goal is to link these phy…

This study tests an online program called OPT-In-Early for parents of 120 toddlers (16-48 months old) on waitlists for an autism diagnosis. The program provides training and support to help parents address their child's developmental needs before a formal diagnosis. Researchers w…

This study looks at how autism affects motor functions like strength, balance, and coordination in adults aged 18 to 45. Researchers will also test whether a 6-week virtual reality training program can help improve these skills. The goal is to better understand the link between m…

This study observes 100 people with rare genetic neurodevelopmental disorders like Baker Gordon Syndrome and Syt-1 disorder. Researchers will track symptoms, collect genetic and imaging data, and create cell models to better understand these conditions. The goal is to improve dia…

This study pairs autistic adults (ages 18-36) with a non-autistic learning partner, like a parent. The autistic adult takes emotional intelligence training, while the partner learns how to better accommodate autism. Both then rate how well the trainings worked for themselves and …

This study is looking at the DNA of 3,800 people with autism to find genetic changes that might be linked to the condition. Researchers hope to better understand which genes are involved and how they affect brain function. The goal is to lay the groundwork for future treatments, …

This study looks at whether a recovery-focused program can help people with severe mental illness living in supported housing. About 72 participants will either receive the new program or standard care. The goal is to see if focusing on personal goals improves daily functioning a…

This study tests a dual executive function training program for 288 primary school children aged 6-12 with ADHD, dyslexia, or autism. The program includes weekly group sessions to improve thinking, emotional control, and behavior. Researchers will measure changes in memory, atten…

This study is creating a registry for children with PTEN Hamartoma Tumor Syndrome (PHTS), a rare genetic condition that increases cancer risk. Researchers will follow 100 participants for 3 years to link genetic changes with health outcomes. The goal is to develop better monitori…

This study looks at whether brain scans can predict which young children with autism (ages 2 to 4) will improve their language skills after 16 weeks of Pivotal Response Treatment (PRT), a behavioral therapy. About 36 children will be randomly assigned to receive PRT right away or…

This study follows 1,000 people who have certain genetic changes (hnRNP and others) that may cause developmental delays, autism, seizures, or muscle problems. Researchers collect medical records, school reports, and questionnaires to see how these gene variants affect behavior, t…

Researchers at UT Dallas are studying whether 'parentese' — the sing-song, high-pitched speech parents often use with babies — helps autistic children learn new words. The study will involve 100 children aged 18 to 59 months, with and without an autism diagnosis. Children will wa…

This study looks at how a brain area called the cerebellum influences social and thinking abilities in young adults with and without autism. Researchers will use a gentle brain stimulation technique and brain scans to see how it changes these skills. The goal is to better underst…

This study is creating a program called START-VET to help veterans with mental illness or substance use disorders who have recently left prison. Researchers will work with 20 veterans to develop transition materials and tools. The goal is to improve quality of life and reduce cri…

This observational study follows 300 adults receiving strategic psychotherapy—a short-term, goal-focused talk therapy—in private practice. Participants fill out questionnaires about their symptoms and well-being before and after treatment. The goal is to see if this therapy leads…

This study tests whether a child-focused goal-setting method called ENGAGE helps children with neurodevelopmental disabilities do better in therapy. About 96 kids aged 5-12 and their therapists will be split into two groups: one using ENGAGE and one using usual care. Researchers …

This pilot study is testing whether a simple saliva test can help doctors prescribe mental health medications more safely and effectively. 200 adults in Manitoba who are starting or changing psychiatric drugs will provide a DNA sample. The results will be shared with their doctor…

This study looks at whether training psychiatric care teams to talk about sexual health with young patients (ages 15 and up) increases those conversations. Researchers will survey 770 teens hospitalized for psychiatric disorders about their sexual health and any side effects from…