Autism
MONDO:0005260Persistent deficits in social interaction and communication and interaction as well as a markedly restricted repertoire of activity and interest as well as repetitive patterns of behavior.
Also known as: autism spectrum disorder, Kanner's syndrome, autism, autism (disease), infantile autism, autism, susceptiblity to, autistic disorder
284 clinical trials for this condition and its sub-types.
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Autism social trial halted: memantine shows no promise
Symptom relief TerminatedThis study tested whether memantine, a medication for Alzheimer's, could improve social skills in youth aged 8-18 with autism or nonverbal learning disability. The trial was stopped early after enrolling only 25 participants. The main goal was to measure changes in social functio…
Phase: PHASE3 • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:08 UTC
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5-Minute wellness program for caregivers shows promise, study cut short
Symptom relief TerminatedThis study tested a program called 5Minutes4Myself, designed to help caregivers of autistic children (ages 8-21) manage stress and improve their well-being. Participants worked with a coach to create a personalized wellness plan and used a phone app with reminders and mindfulness…
Phase: NA • Sponsor: University of Wisconsin, Madison • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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Glutathione study for autism fizzles out early
Symptom relief TerminatedThis study aimed to see if taking glutathione by mouth is safe and practical for children and teens with autism. Researchers planned to enroll 24 participants but stopped early with only 6. The goal was to measure changes in behavior and social skills over 12 weeks.
Phase: PHASE4 • Sponsor: University of Chicago • Aim: Symptom relief
Last updated Jun 26, 2026 18:02 UTC
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Brain and eye clues to emotion recognition in autism and psychosis
Knowledge-focused TerminatedThis study aimed to understand why people with autism or schizophrenia sometimes struggle to recognize emotions on faces. Researchers used brain wave recordings (EEG) and eye-tracking to see how participants processed facial expressions. The study included people with autism, sch…
Phase: NA • Sponsor: Hôpital le Vinatier • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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Brain scans reveal how autistic people process sensory overload
Knowledge-focused TerminatedThis study aimed to understand why people with autism often feel overwhelmed by sensory input like bright lights or loud noises. Researchers planned to use virtual reality and brain scans to see how the brain reacts to unpleasant visual stimuli. The study was terminated early and…
Phase: NA • Sponsor: University of Nebraska • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC