Which home test gets more people screened for colon cancer?

NCT ID NCT05714644

Completed Knowledge-focused Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared two at-home colorectal cancer screening tests—FIT and Cologuard—in over 5,000 patients at community health centers. Participants were mailed a test kit and asked to complete it at home. The goal was to see which test had higher completion rates and was more practical for these clinics. Results will help improve screening equity in diverse communities.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: FIT kit and Cologuard screening tests
What this could lead to: If successful, this could help clinics choose the most effective home test for colorectal cancer screening, especially in underserved communities.
What could go wrong: This is a completed study comparing two existing tests, not a new treatment. Results may not apply to all populations or settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLORECTAL CANCER

Contacts and locations

Locations

Great Plains Tribal Leaders Health Board

Rapid City, South Dakota, 57703, United States
Mass General Brigham

Boston, Massachusetts, 02114, United States
UCLA

Los Angeles, California, 90095-1772, United States

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