Gas therapy may shield kidneys during heart surgery
NCT ID NCT02836899
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether breathing in nitric oxide during and after heart surgery can prevent acute kidney injury. It included 250 adults with signs of blood vessel problems who were having long heart surgeries. Patients received either nitric oxide gas or a placebo (nitrogen) during their procedure. The goal was to see if the treatment reduced kidney damage and the need for dialysis.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- inhaled nitric oxide
- What this could lead to
- If it works, this could provide a way to prevent kidney damage after heart surgery, reducing the need for dialysis.
- What could go wrong
- This trial is completed, but results may not apply to all patients. The benefit may be small or limited to those with specific risk factors.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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