Precision proton beam aims to zap liver tumors with fewer side effects
NCT ID NCT00976898
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested proton beam radiation, a highly targeted form of radiotherapy, in 83 people with liver cancer that could not be surgically removed. The goal was to see if this precise approach could control tumors while reducing damage to healthy tissue. Participants received daily treatments for three weeks, and researchers tracked tumor control and survival over two years.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Proton beam radiation
What this could lead to
If successful, this could offer a more precise and safer radiation option for people with liver cancer that cannot be removed by surgery.
What could go wrong
This is a small, early-phase study with no comparison group. Results may not apply to all liver cancer patients, and some may still experience side effects or tumor regrowth.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02115, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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University of Pennsylvania, Roberts Proton Facility
Philadelphia, Pennsylvania, United States
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University of Texas MD Anderson Cancer Center
Houston, Texas, 77030, United States