Insomnia

This trial tests whether different intensities of breathing exercises (inspiratory muscle training) can improve diaphragm function, thinking, sleep, and mood in young adults aged 18-25 who have low muscle mass. Participants will be randomly assigned to high-intensity, moderate-in…

This study tests whether adding the sleep medication suvorexant to standard buprenorphine treatment can improve sleep and medication adherence in people with opioid use disorder who have recently used fentanyl. Participants first stay in a residential setting for five days to sta…

This trial investigates whether structured exercise—either aerobic cycling or resistance training—can improve health-related biomarkers in women with breast cancer undergoing neoadjuvant therapy (chemotherapy or endocrine therapy before surgery). The main focus is on changes in K…

This study tested whether taking a melatonin supplement (3 mg each night for 6 months) could improve sleep, thinking skills, and blood sugar control in 70 adolescents with type 1 diabetes. Half received melatonin and half received a placebo. The researchers measured changes in bl…

This study compared two types of home dialysis for people with end-stage kidney disease: nighttime automated dialysis (APD) and daytime manual dialysis (CAPD). 137 non-diabetic adults tried each method for 12 weeks. The goal was to see if nighttime dialysis was as good as daytime…

This study tested whether adding the sleep medication lemborexant (Dayvigo) to the standard alcohol craving drug naltrexone helps people with alcohol use disorder and insomnia. Eight adults took either the combination or naltrexone plus a placebo. Researchers measured alcohol cra…

This completed study tested whether painting metal roofs with a special heat-reflecting coating can lower indoor temperatures and improve health in Niue, a Pacific island nation facing record heat. Researchers enrolled 288 adults living in single-story homes with metal roofs. The…

This study tested if transplanting healthy gut bacteria (fecal microbiota) can help people with chronic insomnia. 80 adults received either the bacteria or a placebo in capsules. Researchers measured sleep quality using sleep tests and questionnaires to see if the treatment impro…

This completed trial in Taiwan tested whether a digital health program helps middle-aged and older adults manage conditions like high blood pressure, diabetes, and high cholesterol. 199 participants from four communities used smart devices to measure their health data at home, wh…

Researchers are testing a new face mask, the Smart Mask V1 System, that uses built-in light sensors to measure blood oxygen (SpO2) and pulse rate. The study enrolls healthy adults aged 18 to 65 who wear the mask while breathing air with gradually lower oxygen levels in a special …

This study explores whether a three-dimensional electronic pulse diagnostic device can accurately identify Traditional Chinese Medicine (TCM) syndromes in people with sleep disorders. Participants undergo pulse measurements and symptom assessments, and the device's results are co…

This study looked at a blood test called Beta-D-glucan (BDG) to see how well it detects invasive fungal infections in people with weak immune systems. Researchers tested 280 patients and checked if two positive results within 15 days confirmed an infection. The goal is to help do…

This study tests whether a 12-week lifestyle program—combining personalized nutrition advice, regular psychological support, and a walking routine—can improve sleep quality and body composition in overweight or obese women aged 60 and older. Participants will be assessed at the s…

This study tested whether telehealth coaching from a nurse, based on cognitive behavioral therapy for insomnia (pCBT-I), could prevent or reduce insomnia and depression in 167 adults with low income or education. Participants had early signs of insomnia and were coached to improv…

This study tested whether giving melatonin, a natural sleep hormone, could prevent delirium (sudden confusion) in elderly patients after major non-cardiac surgery. Researchers enrolled 88 patients aged 65 and older across multiple hospitals. The goal was to see if a larger trial …

Researchers compare two six-week stress-management programs for female hospital nurses and midwives: heart rate variability biofeedback and eurythmy therapy. Participants are assigned at random to one program. Before and after, questionnaires and heart rate measurements track cha…

Researchers are testing whether the 4-7-8 breathing technique can reduce anxiety, ease symptom burden, and improve sleep quality in people receiving chemotherapy. The trial enrolls 64 adults undergoing their third treatment cycle, splitting them into a group that practices the br…

This study tested two non-drug methods—reflexology (foot massage) and sleep hygiene education—to improve sleep and comfort in 60 adults on hemodialysis. Both approaches helped, but reflexology was more effective. The results suggest a simple, drug-free option for better rest in d…

This study tests whether an 8-week forest therapy program—combining walking, resistance band exercises, and sensory activities like aromatherapy—can improve muscle strength and well-being in older women with sarcopenia. Thirty-six women aged 55 and older will participate in 16 se…

Many people on long-term hemodialysis struggle with persistent pain at night and poor sleep, which lowers their quality of life. Researchers are testing a nurse-led Benson's relaxation program to see whether it reduces night pain intensity and improves sleep quality. The study en…

Researchers are testing whether cognitive behavioral therapy for insomnia (CBT-I) can improve blood sugar control in older Chinese adults with type 2 diabetes and insomnia. The trial compares CBT-I to usual care in 214 participants aged 60 and older. They will measure changes in …

Researchers are testing whether cognitive behavioral therapy for insomnia (CBT-I) can help returning veterans who drink heavily. The trial enrolls veterans deployed after September 11, 2001, who have insomnia and at least one heavy drinking episode in the past month. Participants…

Researchers at the University of Sfax are testing whether the timing of exercise changes its benefits for sleep and well-being. They enroll 102 sedentary university students aged 18 to 25 and assign them to three weekly 50-minute sessions, two weekend 75-minute sessions, or a con…

Researchers are testing whether a 10-session mechanical massage program can improve sleep quality, lower stress hormones, and affect immune function in people who report high stress and poor sleep. The study enrolls 32 adults who score high on stress and insomnia questionnaires a…

Researchers at Ataturk University are testing whether watching nature videos through virtual reality glasses can improve sleep quality and mental well-being in people with multiple sclerosis. The trial enrolls 42 adults aged 18 to 80 who have MS and are not in an attack. One grou…

This study tested a combination of platelet-rich plasma (PRP) from the patient's own blood and hyaluronic acid injected into the jaw joint. Twenty-two adults with painful clicking and limited mouth opening received the treatment. Researchers used a jaw tracking device to measure …

This study tests a phone-based sleep therapy for people who have insomnia and drink alcohol in ways that could harm their health. The therapy adapts standard insomnia treatment to also address alcohol-related thoughts and behaviors. Researchers will first refine the approach with…

This trial tests whether ozone autohemotherapy, a procedure where a person's blood is mixed with ozone and put back into their body, can improve sleep in people who have insomnia after an ischemic stroke. Researchers will measure sleep quality and look at blood markers of inflamm…

This trial tests whether listening to music for 20 minutes can improve sleep quality and reduce risk perception in pregnant women hospitalized due to the threat of premature birth. Researchers will measure sleep using the Richard Campbell Sleep Quality Scale and risk perception w…

This study tests whether a non-electric, hand-held temple massager—used daily for 4 weeks with a special lotion and optional lavender aromatherapy—can lower stress, improve emotional wellbeing, sleep quality, and overall quality of life in women aged 35 to 65. Participants use th…

This trial tests whether zolpidem, a common sleep medication, can improve sleep quality and reduce painkiller use in adults recovering from total knee replacement. Half of the participants take zolpidem 10 mg each night for two weeks after leaving the hospital, while the other ha…

This study tested two sleep medications (suvorexant and zolpidem) against a placebo in 40 adults with Progressive Supranuclear Palsy (PSP). The goal was to see if targeting the brain's wake-promoting system could improve sleep quality and daytime well-being. Each person tried all…

This trial tests whether coaching older adults in healthy habits or sleep habits can improve their recovery after hip or knee replacement surgery. Participants receive four hour-long sessions with a therapist, focusing either on general healthy habits like physical activity and n…

This trial tests whether wearing a grounding patch at night improves sleep quality in cancer patients who have insomnia while in the hospital. The patch is a hydrogel sticker on the forehead, connected by a cord to a true earth connection, which may lower the body's electrical vo…

This trial tests whether a nurse-led program of sleep hygiene education and progressive muscle relaxation can improve sleep quality in obese pregnant women. Researchers will enroll 100 women in their third trimester with a BMI of 30 or higher and sleep problems. Half will receive…

This study tests a smartphone app called BELL-001 that plays personalized sounds in sync with your breathing to help you relax and fall asleep. 114 adults with insomnia will use the app or a sham version nightly for 4 weeks. Researchers will measure changes in sleep quality and d…

This trial tests whether progressive muscle relaxation, kinesio taping, or both can reduce premenstrual syndrome symptoms like stress, depression, and poor sleep in university students. Participants are randomly assigned to one of four groups: relaxation exercises, taping, both, …

This trial tests whether sleeping with a traditional Chinese medicine herbal sachet can ease insomnia and improve sleep quality in adults aged 60 and older. Participants will place the sachet near their head each night for eight weeks, with some receiving a placebo sachet for com…

This trial tests whether a structured program combining psychoeducation, breathing exercises, and relaxation techniques can reduce post-traumatic stress symptoms and improve sleep quality in adults who survived the February 2023 earthquakes in Türkiye. Ninety participants living …

This trial tests whether a traditional Chinese medicine aromatic sachet, placed beside the pillow each night, can improve sleep quality in women aged 45 to 59 experiencing poor sleep during the menopausal transition. One hundred twenty-two women in Macao will use either the herba…

This trial tests whether a daily sleep gummy can improve sleep quality and quantity in adults aged 20-50 who have self-reported sleep issues. Participants take one gummy before bed for 7 days while wearing a Fitbit tracker to measure sleep patterns. The study compares sleep metri…

This trial tests whether a topical roll-on and diffuser blend can improve sleep quality and duration in adults who have had sleep issues for the past month. Over six weeks, 40 participants will use the diffuser blend at night for three weeks, then switch to the roll-on applied to…

This trial tests whether a 20-minute foot massage, given daily for three days after open heart surgery, can reduce pain, improve sleep quality, and boost mood. Adults undergoing coronary artery bypass grafting who report significant pain after surgery are randomly assigned to rec…

This trial tests whether an educational program delivered via telemedicine can improve sleep quality, sleep habits, and physical activity in medical students with poor sleep. Participants are randomly assigned to receive the same sleep education either remotely or in person. Slee…

This study is testing whether special drug-free patches can help relieve acute back, shoulder, or other muscle pain and improve sleep. The patches use a gentle vibration technology instead of medication. 150 adults aged 18-64 will wear either an active patch or a sham (fake) patc…

This study tests whether practicing MediYoga—a gentle form of yoga—through a smartphone app can improve sleep quality, lower blood pressure, and boost quality of life in people aged 65 and older who have hypertension. Participants will be randomly assigned to do 20 or 40 minutes …

This trial tests whether progressive muscle relaxation and deep breathing exercises can help people with COPD feel less tired and sleep better. About 90 participants will be split into three groups: one practicing muscle relaxation, one doing deep breathing exercises, and a contr…

This trial tests whether different combinations of cannabinoids—THC, CBN, CBG, CBD, and melatonin—taken as gummies can improve sleep quality in adults aged 21 to 55 who report poor sleep. Participants will be randomly assigned to receive one of several active gummy formulas or a …

This study tested whether a Persian-language internet program called Omid, based on cognitive behavioral therapy, can improve sleep in adults with insomnia. Thirty participants were randomly assigned to use the program or receive usual care. The program includes weekly online les…

This pilot study explores whether cancer patients are willing to complete a quick self-screening for insomnia during clinic visits, and whether a video-based cognitive behavioral therapy (CBT-I) could help them sleep better. The study involves adults with breast, colorectal, lung…

This trial tests whether a group-based psychological treatment for insomnia, adapted for people with depression, anxiety, or PTSD, can improve sleep and reduce psychiatric symptoms. Participants receive either the adjusted CBT-i program or usual care. The study measures changes i…

This study tests two simple activities—pedaling a stationary bike and using a breathing device—during dialysis sessions to see if they reduce fatigue and improve sleep. 102 adults on hemodialysis will be split into three groups: one does leg exercises, one does breathing exercise…

This study looks at whether Tai Chi, a gentle moving meditation, can improve chronic insomnia in breast cancer survivors. About 90 women who have completed cancer treatment and have had trouble sleeping for at least 6 months will practice Tai Chi. Researchers will measure sleep q…

This study tested whether taking 400 mg of magnesium citrate daily for 90 days could improve sleep quality and cognitive function in healthy Saudi adults who reported poor sleep. Researchers compared 41 participants who took the supplement to a control group that took nothing. Th…

This trial tests whether TECAR therapy, a non-invasive device that delivers energy to painful areas, can reduce pain in people with fibromyalgia. About 46 adults with fibromyalgia will receive either real or sham TECAR sessions twice a week for three weeks. Researchers will measu…

This trial tests whether therapeutic touch or foot reflexology can improve sleep quality and ease menopausal symptoms in postmenopausal women who lived through the 2023 Kahramanmaraş earthquakes. About 155 women will be randomly assigned to receive one of the two therapies or to …

This study tests whether chair-supported yoga can improve sleep quality and reduce pain in people aged 65 and older who live in nursing homes. Participants will be randomly assigned to either attend chair yoga sessions twice a week for 8 weeks or receive routine care only. The tr…

This trial tests whether a 6-week virtual Tai Chi and Qigong program can improve sleep quality in adults aged 50 and older. Participants take three 50-minute online classes per week, with some starting immediately and others waiting six weeks. Researchers measure sleep quality an…

This study looked at whether an 8-week group exercise program could improve physical abilities and sleep in adults aged 65 to 90. Eighty participants from community centers in Taiwan either joined the exercise program or continued their usual activities. The program included aero…

This study asks whether Su Jok therapy, a complementary technique that gently stimulates specific points on the hands, can reduce shortness of breath and improve sleep in adults with asthma. Participants will be randomly assigned to receive either Su Jok therapy alongside their u…

This study tests whether a mobile app can help people with gastroesophageal reflux disease (GERD) reduce symptom recurrence and improve sleep quality and quality of life. Participants with confirmed GERD will be randomly assigned to either use the app—which provides education, li…

This trial tests whether a structured nurse-led program can improve sleep quality in adults with chronic heart failure. Participants will receive education on healthy sleep habits and cognitive-behavioral techniques, alongside their usual care. The study measures changes in sleep…

This trial tests whether a set of EMF protection devices—including pads, chips, and bands—can improve sleep quality and energy levels in adults aged 30-60 who have trouble sleeping. Participants use all devices daily for about four weeks while tracking sleep with a wearable ring …

This study explores whether an AI-powered chatbot can deliver personalized sleep coaching to Black/African American adults aged 18-25 who have poor sleep and at least one cardiometabolic risk factor. The chatbot uses principles of cognitive-behavioral therapy for insomnia (CBT-I)…

This study tests whether online cognitive-behavioral therapy (CBT) for insomnia, combined with CBT for pain, can reduce headaches and improve sleep in adolescents aged 11-17 who have both migraine and insomnia. Participants receive internet-delivered programs focusing on sleep hy…

This pilot study tests whether cognitive behavioral therapy for insomnia (CBT-I) can improve sleep in Chinese adults with chronic insomnia. CBT-I is a non-drug approach that combines techniques like stimulus control, sleep restriction, and relaxation therapy. The study measures c…

This study tested a 16-week sensory-friendly physical activity program for autistic children aged 7-12 in special education schools. The program included predictable routines and calming cool-downs to help with sleep. Researchers measured sleep quality using wrist monitors and pa…

This pilot study tested whether wearing bright light therapy glasses can improve sleep and reduce cravings in people being treated for opioid use disorder. Twenty-three adults on stable medication-assisted treatment (methadone or buprenorphine) with insomnia used either active or…

This trial tests whether a mobile health app called mTranS-C can improve sleep quality in adolescents who are at risk for depression and anxiety but do not yet have a psychiatric diagnosis. The app delivers a behavioral sleep intervention designed to address insomnia and delayed …

This trial tests whether the sleep medication suvorexant can improve restorative sleep and reduce insomnia in older adults recovering from elective surgery. Participants aged 50 to 90 who have a history of insomnia will receive either suvorexant or a placebo during their hospital…

This study tests whether a virtual cognitive behavioral therapy program can help people with cirrhosis who also have trouble sleeping. Ten adults with cirrhosis and insomnia will try the program from home. The goal is to see if the program is easy to use and helpful for improving…

This study tests whether a medication called RE03 (dexmedetomidine), already used in intensive care, can improve sleep in people with PTSD who have trouble sleeping or nightmares. Twenty-four adults with PTSD will receive either the drug or a placebo in random order, and their sl…

This study tested whether bright light therapy could help people with multiple sclerosis who have trouble sleeping. 27 participants used a light box at home. The goal was to see if it was safe and if it improved sleep and daily function.

This pilot study tests whether listening to specially designed audio patterns (Brain Dynamic Audio Stimulation) for 30 minutes daily can improve sleep in healthcare workers with insomnia. Fifteen participants will use the audio for two weeks, and researchers will measure changes …

This study tested if an app that teaches better sleep habits could help people with long-term pain and insomnia. 105 adults in a 4-week rehab program either got the app or standard care. The goal was to see if the app improved sleep quality more than rehab alone.

This study tests whether personalized advice on sleep timing, light exposure, meal times, and physical activity can improve sleep quality in adults aged 65 and older who have poor sleep. Participants are randomly assigned to receive either general sleep advice or a customized pla…

This study tests whether taking magnesium L-threonate for six weeks improves sleep quality, mental focus during fatigue, and muscle function in healthy adults aged 18 to 45. Participants receive either the supplement or a placebo, and researchers measure sleep scores, reaction ti…

This study tested whether an online program for insomnia (called SHUTi) could help heavy drinkers reduce their alcohol use. 113 adults who drank heavily and had trouble sleeping took part. The goal was to see if improving sleep would also lead to less drinking and fewer binge epi…

This study tests whether a daily supplement called NPQ Plus can improve skin health, antioxidant status, fatigue, and well-being in healthy adults with minor skin concerns like dryness or itchiness. The supplement contains polyphenols, NMN, PQQ, CoQ10, and minerals. Participants …

This study tests whether an online guide based on Acceptance and Commitment Therapy (ACT) can help college students with insomnia. Participants will either receive the online ACT program or be placed on a waitlist. The program includes sleep education, mindfulness skills, and beh…

This study tests a smartphone app called Sleepio that teaches teens with insomnia how to sleep better using cognitive behavioral therapy. The participants are 14- to 18-year-olds who have recently been hospitalized for suicidal thoughts or attempts. The goal is to see if improvin…

This study tested whether walking while doing simple mental tasks (like memory or attention exercises) can help older adults with brain fog. 90 people aged 65+ took part, either walking with cognitive tasks or walking only, three times a week for four weeks. Researchers measured …

This study tests whether an 8-week aquatic high-intensity interval training (HIIT) program can improve balance, physical function, and muscle health in people with Parkinson's disease. Fifty-six participants with mild to moderate Parkinson's will do Tabata-style exercises in a po…

This completed study tested two ways to improve sleep in children aged 1 to 7 years: a mobile app (Storybook) that guides caregivers through calming bedtime activities, and face-to-face sessions teaching sleep hygiene and routines. Sixty families in Ecuador took part over one mon…

This trial tests whether a very low dose of two drugs—dexmedetomidine and esketamine—given at night can improve sleep quality in older adults (65-89 years) undergoing knee or hip replacement. Poor sleep after surgery is common and linked to worse recovery. The study compares the …

This phase 3 study tests whether YZJ-1139 tablets help adults with insomnia fall asleep faster and sleep more efficiently. Participants receive either 20 mg, 40 mg, or a placebo daily for two weeks. Sleep is measured using both sleep diaries and overnight lab tests.

This clinical trial tests whether a new drug called YZJ-1139 can help people with insomnia sleep better than the commonly used medication zolpidem. Adults aged 18 to 64 with insomnia disorder take either YZJ-1139 or zolpidem daily for 28 days. Researchers measure sleep quality us…

This study tested whether Benson relaxation exercises can improve sleep quality in cancer patients. 72 adults with cancer were randomly assigned to do relaxation exercises or receive a sleep hygiene booklet. The goal was to see if this simple, non-drug method could help with slee…

This study tested whether adding telehealth coaching to a digital cognitive behavioral therapy program helps people with insomnia complete the treatment. 700 adults with insomnia were enrolled. The goal was to see if coaching improves adherence and reduces disparities in who bene…

This study tested whether daily gummies containing L-theanine and lion's mane mushroom extract could reduce stress, anxiety, and improve sleep in university students. 67 students aged 18-25 took either the gummies or no supplement for 8 weeks. The goal was to see if this natural …

This study tests if group cognitive behavioral therapy (CBT) can reduce anxiety and insomnia in teens aged 12-20. About 171 participants with both conditions will receive either CBT for anxiety or CBT for insomnia. The goal is to see which approach better improves symptoms, sleep…

This study tested whether a noninvasive device that gently stimulates a nerve in the ear (taVNS) could help breast cancer patients with insomnia. Twenty adults with stage I-IV breast cancer who had trouble sleeping for at least three months took part. The main goal was to see if …

This study tests two short behavioral therapies delivered over video calls for adults with chronic orofacial (jaw or face) muscle pain and insomnia. One therapy focuses on sleep habits and routines; the other uses jaw relaxation and breathing exercises. The goal is to see which a…

This study tests whether cognitive behavioural therapy for insomnia (CBT-I) can improve sleep and ADHD symptoms in adolescents aged 12 to 18 who have both ADHD and insomnia. Participants receive either CBT-I plus usual care or usual care alone. The goal is to see if addressing in…

This study tested whether teaching good sleep habits could help people with painful diabetic nerve damage sleep better and feel better overall. Twenty-four patients were split into two groups: one received a booklet and face-to-face sleep training from a nurse, while the other co…

This study tested whether an AI-guided writing program could help teens feel less anxious, depressed, or stressed. Over three days, 486 Chinese adolescents wrote about negative experiences, with some receiving personalized AI feedback. The goal was to see if this simple, digital …

This study tested a technique called cryo-auriculotherapy, where a device freezes specific spots on the ear, to see if it helps people with chronic insomnia. Sixty-five adults with moderate to severe insomnia received either real or sham (fake) treatments over three months. The m…

This study tested whether reducing non-urgent nighttime medical interruptions helps hospitalized adults sleep better. 51 patients wore Fitbits to track sleep and completed sleep quality surveys. One group had adjusted nighttime orders with fewer interruptions, while the other rec…

This trial tests whether applying platelet-rich fibrin (PRF) — a wound dressing made from a patient's own blood — to the roof of the mouth after gum graft surgery improves pain, sleep, and overall quality of life compared to standard dressings. About 78 adults needing gum surgery…

This study looked at whether watching a video through virtual reality goggles with music can reduce pain and improve sleep quality in women with period pain (dysmenorrhea). 77 women aged 15-49 with moderate to severe pain used either VR with music or just music alone for 3 days. …

This study tested a text-message chatbot called Cecebot that combines sleep therapy and activity tips to help breast cancer survivors with insomnia. 60 women with stage I-III breast cancer and poor sleep used the chatbot for 6 weeks. The goal was to see if it was easy to stick wi…

This study tested whether eye masks and calming audiobooks could improve sleep for children aged 6-15 in the pediatric intensive care unit. Forty-two children were randomly assigned to use these tools or receive standard care. Researchers measured sleep quality and vital signs to…

This study tested a six-session behavioral sleep program, called Apnea and Insomnia Relief (AIR), in 118 Gulf War veterans with Gulf War Illness. The program combined sleep education, motivation for using a breathing machine, and insomnia therapy, all done via telehealth. Researc…

This study looked at whether taking gac fruit oil capsules for 30 days could help adults aged 40 to 65 who have trouble sleeping. The 50 participants took four capsules daily and were tested on sleep quality, vision, mood, and brain scans before and after. The goal was to see if …

This study looked at whether a 4-week behavioral sleep program could improve both sleep and thinking in 62 older adults with chronic insomnia. Participants learned sleep habits, relaxation, and adjusted their bedtimes. The researchers measured sleep changes and daily thinking per…

This study tested two sleep medications, trazodone and eszopiclone, in 673 veterans with PTSD-related insomnia. The goal was to see if these drugs could reduce insomnia symptoms over 12 weeks. Participants were adults aged 18-75 with military-related PTSD and insomnia. The study …

This completed trial tested whether combining online acceptance and commitment therapy (ACT) with customized sound therapy helps people with tinnitus and insomnia. 164 adults were split into two groups: one received both therapies, the other only sound therapy. The goal was to se…

This study tested whether a 14-day course of the sleep medication eszopiclone could help people with both insomnia and obstructive sleep apnea use their CPAP machine more consistently. Sixty participants were randomly assigned to receive either eszopiclone or a placebo. The resea…

This study tested a new daily supplement called KGA-10 (a heat-killed bacterium) in 107 healthy adults to see if it could lower stress, reduce inflammation, and improve sleep and general well-being. Participants took either the supplement or a placebo for 8 weeks and completed su…

This study followed 90 Canadian adults with insomnia who were prescribed daridorexant. Researchers tracked changes in quality of life, work productivity, and sleep symptoms over three months using questionnaires. The goal was to see how the medication helps people in everyday lif…

This small study tested a dietary supplement called NatureU Sweet Dream, which contains GABA and Lactium, against a standard melatonin product in 17 adults with mild to moderate sleep problems. Participants wore a sleep tracker to measure deep sleep duration and percentage. No si…

This study tested whether laughter yoga and sleep hygiene training could help university students with premenstrual syndrome (PMS). 45 female students took part in 4 weekly 45-minute laughter yoga sessions plus sleep hygiene advice. Researchers measured changes in PMS symptoms, s…

This study tested a home-based brain-training program in 12 autistic adults who also had insomnia. Participants played cognitive games for 18 hours over 6 weeks while wearing a sleep tracker and filling out sleep diaries. The goal was to see if the training was usable and could i…

This study tested two types of therapy for insomnia in 134 people also being treated for alcohol use disorder. The goal was to see if improving sleep could help them stay sober and feel better during the day. Participants received either a standard insomnia treatment or a tailore…

This study tested whether a medication called solriamfetol, cognitive behavioral therapy for insomnia (CBT-I), or both together can help people with insomnia sleep better and feel less tired during the day. 115 adults with insomnia took part. The goal was to see if staying awake …

This study tested a dietary supplement called Speed Sleep in 60 adults aged 18-65 who have trouble sleeping. Participants took either the supplement or a placebo daily for 4 weeks. Sleep quality and quantity were measured using Fitbit trackers and questionnaires.

This study tested whether a guided meditation called yoga nidra is practical and helpful for people with PTSD and insomnia. Sixty adults who had experienced a stressful or traumatic event and had trouble sleeping took part. They listened to online recordings daily for 8 weeks, an…

This early-stage study tested a new insomnia drug called HEC83518 in 74 healthy Chinese adults aged 18 to 45. The main goal was to check safety and side effects after a single dose. Researchers also measured how the drug moves through the body. This is a first step to see if the …

This early-stage trial tested a new drug called HEC83518 in 57 healthy Chinese adults to see if it is safe and how the body processes it. Participants took the drug or a placebo daily for 15 days. The study focused on side effects and drug levels in the blood, not on whether it i…

This study tested a 3-month walking program for Spanish-speaking Latinos aged 55 and older with mild cognitive impairment. Participants walked in groups twice a week, then received motivational phone calls for another 3 months. Researchers measured changes in physical activity, t…

This small study tested whether combining digital cognitive behavioral therapy for insomnia (CBT-I) with sessions in a sauna blanket is feasible for adults with insomnia. Ten participants used an online CBT-I program and a sauna blanket at home for 9 weeks. The goal was to see if…

This completed trial tested PeptiSleep, a plant-based supplement made from rice protein, to see if it improves sleep quality in healthy adults. 120 participants took either PeptiSleep or a placebo daily for 6 weeks while wearing a sleep tracker and completing surveys. The study m…

This study tested a cognitive behavioral therapy (CBT) course for insomnia in 73 adults who also have a chronic physical illness like arthritis, heart disease, or cancer. The therapy focused on changing sleep habits and thoughts about sleep. Results showed that the course helped …

This study tested a 10-week digital detox program for 160 teens aged 10-19 who use smartphones at least 3 hours daily. The program included weekly sessions on reducing screen use, setting goals, and improving sleep habits. Researchers measured changes in screen addiction, sleep q…

This completed study tested whether progressive relaxation exercises could help patients sleep better after urological surgery. Two adults aged 18 or older, with no sleep disorders, practiced tensing and relaxing muscles while focusing on breathing. The goal was to see if this si…

This study tested whether laughter yoga could help women in menopause who struggle with brain fog, low mood, and poor sleep. 97 women were split into two groups: one did 8 sessions of laughter yoga over 4 weeks, and the other did nothing. Researchers measured brain fog, psycholog…

This study tested two pelvic floor muscle strengthening methods—EMG-biofeedback and rebound therapy (gentle bouncing)—in 42 women with endometriosis. The goal was to see which better reduces pain, improves muscle strength, and boosts quality of life. Participants had moderate to …

This study tested the DOZE app, a digital self-management program designed to improve sleep in young adults aged 18-25 with chronic pain and insomnia. Forty participants used the app and a sleep diary for 10 weeks. The goal was to see if the app is easy to use and helps with pain…

This study tested whether taking melatonin before bed can reduce pain and improve sleep in people with chronic low back pain and insomnia. About 220 adults aged 18 to 64 with back pain for at least 3 months and sleep problems took either melatonin or a placebo for several weeks. …

This study looked at whether Reiki, a hands-on relaxation technique, can reduce pain, fatigue, and improve sleep in older adults living in nursing homes. Sixty people aged 50 and older with chronic pain took part. They received Reiki sessions over four weeks, and researchers meas…

This study tested whether partial-body cryotherapy (standing in a very cold chamber for 2-3 minutes) could help reduce fatigue in people with multiple sclerosis during a rehabilitation stay. 43 participants received either real cryotherapy at -120°C or a sham version at -30°C ove…

This study tested whether an online program for insomnia could help veterans with COPD sleep better and feel better. 13 veterans were randomly assigned to either the online insomnia treatment or online education about sleep. The goal was to see if the treatment improved sleep qua…

This study tested whether a type of talk therapy called Acceptance and Commitment Therapy (ACT) can improve sleep in adults with insomnia. 93 participants were randomly assigned to either receive ACT for 7 weeks or join a waitlist. The therapy encourages people to stop struggling…

This study looked at whether kinesio taping (a special elastic tape placed on the skin) can quickly ease period pain and related symptoms like trouble sleeping and fear of moving. Researchers compared real taping to a fake (sham) taping in 24 women aged 18-24 with primary dysmeno…

This study looked at whether eating microgreens can improve sleep patterns in athletes. Twenty active athletes without heart disease took part. Researchers measured sleep stages, total sleep time, and muscle soreness to see if microgreens help with recovery and rest.

This study looked at whether a short sleep therapy program (BBTI) can improve sleep and help people stay in treatment for substance use disorders. About 83 adults living in a residential recovery program took part. They wore sleep trackers, completed surveys, and did sleep diarie…

This study tested whether the sleep medication suvorexant (Belsomra) can reduce insomnia severity and improve metabolic health in midlife women who have both insomnia and signs of metabolic syndrome. Thirty-one healthy women aged 40-65 who were perimenopausal or postmenopausal to…

This study looked at whether a 12-week exercise program could help older adults become less frail, improve their memory and thinking, and get better sleep. 110 adults aged 65 and older took part. The program included group exercise sessions twice a week. Researchers measured frai…

This study tested whether teaching menopausal women about good sleep habits (sleep hygiene) could improve their sleep and comfort. Sixty women were split into two groups: one received the education, the other did not. Researchers measured sleep quality and comfort before and afte…

This study tested whether combining virtual reality (VR) with aromatherapy could improve the mental well-being of older adults living in care homes. 48 participants used VR and scents to see if it boosted happiness, reduced stress, improved sleep, and increased life satisfaction.…

This study tested a sleep improvement program for people with cancer and their intimate partners who also have sleep problems. The goal was to reduce insomnia and improve sleep quality. Only 2 couples took part, so results are very limited.

This study tested an online program to help cancer patients with insomnia. It included 348 adults with cancer who had trouble sleeping. The program used cognitive-behavioral techniques and aimed to see who might need extra help from a professional.

This study tested a version of cognitive behavioral therapy for insomnia, specially adapted for night shift workers. 60 nurses who work night shifts and have insomnia took part. The goal was to see if the therapy is practical and helps improve sleep and reduce fatigue.

This study tested whether Eschscholzia tablets, a herbal product, can help adults with insomnia sleep better. 104 people took either the tablets or a placebo for 4 weeks, and neither they nor the researchers knew who got which. The goal was to see if the tablets improve sleep qua…

This study tested a mobile app called PCYCARE in 120 first-time pregnant women in their third trimester. The app provides educational modules and guided relaxation sessions over 21 days. Researchers measured changes in anxiety, sleep quality, and childbirth preparedness compared …

This study tested two programs to help older adults stop taking sleeping pills like lorazepam or zolpidem. One program focused on placebo effects—the power of believing a treatment works—while the other did not. Both included cognitive behavioral therapy and special pill packagin…

This study looked at whether progressive relaxation exercises can help people with type 2 diabetes who have nerve pain, fatigue, and poor sleep. 88 adults took part. The goal was to see if these simple exercises could improve their symptoms and quality of life.

This study tested a device called BTL-699-2 in 43 adults to see if it could improve sleep quality and reduce stress. Participants received six treatments and filled out questionnaires about their sleep and stress levels. The goal was to find a non-drug way to help people sleep be…

This study looked at whether teaching primary care doctors better ways to treat insomnia can help their patients sleep better. About 485 patients with insomnia symptoms completed surveys. Researchers compared patients whose doctors received special training with those getting usu…

This study tested whether teaching women in menopause about good sleep habits (sleep hygiene) could improve their sleep quality and reduce common menopause symptoms like hot flashes and mood changes. Seventy women who had not had a period for at least a year took part. They recei…

This study tested an online program called SLEEPexpert that teaches behavioral techniques to improve sleep in people with mental disorders. 68 psychiatric inpatients with insomnia used the program alongside their usual treatment. The goal was to see if it helps reduce insomnia an…

This study tested whether a six-week sleep therapy program (CBT-I) could improve thinking and memory in older adults aged 60-85 with insomnia. Two hundred participants were randomly assigned to either CBT-I or a sleep education program. A small group also had brain scans to see i…

This study tested whether wearing an eye-ear sleep band, which blocks light and noise, could improve sleep quality in 100 adults admitted to a coronary care unit with acute coronary syndrome. Each patient spent one night with the band and one night with standard care, in random o…

This small study tested a robotic device that massages the back to see if it helps people with Parkinson's disease move better, feel less back pain, and sleep better. Nineteen adults with mild to moderate Parkinson's took part in four 40-minute sessions over two weeks. The result…

This study looked at whether drinking tart cherry juice can improve sleep in older adults with insomnia. Twenty people aged 65 and older drank cherry juice and a placebo for 4 weeks each while wearing a sleep tracker. Researchers checked if the study was easy to follow and measur…

This study tested a sleep medication called lemborexant in 82 adults with liver cirrhosis who had trouble sleeping. The drug works by blocking wakefulness signals in the brain. Researchers measured sleep quality and checked for side effects on the liver. The goal was to see if le…

This study tested whether acupressure—a technique using finger pressure on specific body points—can improve pain, anxiety, sleep quality, and the sense of nursing presence in intensive care patients. Sixty adults in the ICU were split into three groups: one received real acupress…

This study tested whether Liuzijue Qigong, a traditional Chinese breathing exercise, could improve lung function in elderly people who had a stroke. 70 participants did either Qigong or standard rehab for 12 weeks. Researchers measured breathing capacity, walking ability, and qua…

This study tested whether teaching COPD patients breathing exercises through short videos could reduce shortness of breath, increase activity, and improve sleep. Sixty adults with COPD followed a 30-day program of pursed-lip and diaphragmatic breathing, guided by a 5-7 minute vid…

This study tested whether a three-week aerobic exercise program could reduce PTSD symptoms and improve sleep in 82 adults who survived the February 2023 earthquake in Turkey. Participants were randomly assigned to either supervised exercise sessions or a control group. Researcher…

This study tested whether using virtual reality (VR) glasses for 30 minutes each evening could improve sleep quality, reduce anxiety, and stabilize vital signs in intensive care patients with COPD. Fifty patients were split into two groups: one received VR sessions for a week, th…

This study tested whether a combination of morning blue light and evening red light therapy could improve sleep in 20 adults with mild sleep complaints. Participants wore a wrist device to track sleep during a normal week and then during a week of light therapy. The goal was to s…

This study looked at whether it is safe for people with a tracheostomy (a breathing tube in the neck) to use a Passy Muir valve while sleeping. The valve helps them speak by redirecting air, but using it at night hasn't been well studied. Researchers monitored 33 patients in a lo…

This study tested a behavioral sleep treatment in 36 veterans who have PTSD, insomnia, and sleep apnea. The goal was to see if improving sleep also improves quality of life and daily functioning. Participants attended therapy sessions and reported their sleep and well-being throu…

This study tested whether a daily mix of plant protein and two herbs (ashwagandha and rhodiola) could improve sleep in 100 adults aged 35-70 with sleep troubles. Participants took either the supplement or a placebo for 30 days and reported their sleep quality daily. The goal was …

This study tested whether practicing pranayama breathing exercises for 15-20 minutes a day, 5 days a week for 8 weeks, could help adults aged 60 and older feel less stressed, sleep better, and enjoy a higher quality of life. Researchers compared 74 participants who did the breath…

This pilot study tested a non-drug device called Bioboosti to see if it could help people with insomnia sleep better. Twenty adults with insomnia used the device, and researchers measured changes in sleep quality and daytime sleepiness. The goal was to find a safe, drug-free opti…

This study tested a 12-week self-management program for university students with chronic fatigue. The program taught skills like goal setting, time management, and stress coping. Researchers measured changes in fatigue, sleep quality, resilience, and daily balance. The goal was t…

This study tested whether a gentle electrical current applied to the scalp (tDCS) can reduce symptoms of major depression, schizophrenia, OCD, generalized anxiety, and insomnia. 320 adults aged 16–65 received multiple sessions over weeks. Researchers measured symptom changes usin…

This study tested whether a 12-week nurse-led program could help people on hemodialysis feel better and function better. 220 patients were split into two groups: one got the extra program during dialysis sessions, and the other got standard care. The program included light exerci…

This study tested daridorexant, a sleep medication, in 166 teenagers aged 10 to 17 with chronic insomnia. Participants took one of three doses of the drug or a placebo each evening. Researchers measured changes in total sleep time using overnight sleep tests and monitored safety.…

This completed Phase 2 trial tested whether Neurexan, a homeopathic tablet, can improve sleep and reduce stress in 81 people with short-term insomnia. Participants took Neurexan or a placebo for 14 days. Sleep efficiency was measured using brain activity and other body signals, w…

This completed study tested four different nutritional supplements against a placebo to see if they could improve sleep quality in healthy adults. A total of 376 people took part over 12 weeks. Researchers measured sleep quality, daytime function, and related symptoms like insomn…

This study tested whether acupressure—a gentle finger-pressure technique on specific body points—could improve sleep, quality of life, and reduce hopelessness in older adults living in a nursing home. Fifty people aged 65 and older took part, with half receiving acupressure three…

This study tested an online sleep education program for young adult cancer survivors (ages 20-39) who have trouble sleeping. Participants took a single online session, with some also getting extra coaching. The goal was to see if it could reduce insomnia and improve mood. The stu…

This study tested whether virtual reality relaxation or binaural beat stimulation can improve sleep and reduce discomfort in 140 adults who had mechanical heart valve replacement. Many patients struggle with sleep due to the sound of the new valve. Participants were randomly assi…

This study tested whether therapeutic touch — a gentle, non-invasive technique — can reduce pain, delirium, and improve sleep in 80 intensive care patients. Researchers measured pain, sedation, sleep quality, and vital signs like blood pressure and heart rate. The goal was to see…

This study tested whether adding brief advice on the Mediterranean diet and physical activity to standard cognitive behavioral therapy for insomnia (CBT-I) could improve sleep quality. Five adults with chronic insomnia participated. Researchers measured sleep quality and insomnia…

This study tested a liposomal magnesium supplement in 60 adults who reported low energy and mood issues. Participants took the supplement daily for 14 days and filled out questionnaires about their energy, mood, and stress levels. The trial was small, short, and had no placebo gr…

This study tested whether adding a virtual coach (phone support) helps veterans with insomnia use a digital cognitive behavioral therapy program for sleep. 244 veterans were randomly assigned to either the digital program with coaching or with minimal contact. The goal was to see…

This study tested an herbal compound in 108 adults who had trouble sleeping and tinnitus (ringing in the ears) but did not want to take sleeping pills. Participants took either a low dose, high dose, or placebo daily for 3 months. Researchers measured changes in sleep quality and…

This pilot study tested a brief cognitive behavioral therapy (CBT) program designed to help older adults (55+) safely reduce or stop their use of benzodiazepines, which are commonly prescribed for insomnia and anxiety but can be risky with age. Seventeen participants received the…

This study tested whether wearing a light-blocking eye mask at night (11 p.m. to 5 a.m.) could improve sleep quality and melatonin levels in 60 intensive care unit patients. Participants were randomly assigned to either wear the mask or receive standard care. Sleep quality was me…

This study tested whether a single online education session can help cancer survivors with insomnia sleep better. 70 survivors took part, learning either behavioral changes to improve sleep or relaxation techniques. The goal was to see if a simple, accessible program could ease i…

This completed Phase 2 trial tested whether a personalized mind-body program could improve sleep in 60 women aged 40–60 who work in healthcare and report short sleep. Participants tried 30-minute sessions of mindfulness, yoga, and guided walking in different orders over 12 weeks.…

This study tested a daily dietary supplement designed to improve sleep in women aged 40 to 65 going through menopause. 128 women with moderate sleep problems were randomly assigned to take either the supplement or a placebo for about three weeks. Sleep quality, nighttime awakenin…

This study looked at whether two types of talk therapy—Behavioral Therapy and Cognitive Therapy—can help Gulf War Veterans who have trouble sleeping. Fifty veterans took part, and their sleep problems were measured using a standard questionnaire. The goal was to see which therapy…

This study tested whether a headband called Muse-S, which senses brain activity, could help midlife women with sleep problems like insomnia. Thirty-one women going through menopause wore the device at home. The goal was to see if it was practical and if it improved sleep quality …

This study tested whether aromatherapy foot massage can reduce pain, improve sleep, and speed recovery after laparoscopic gallbladder removal. 103 adults received two 10-minute foot massages with essential oils after surgery. Researchers measured pain, sleep quality, and recovery…

This study tested an app called EMPOWER-ED that provides education and tools to help veterans reduce or stop taking benzodiazepines (like Xanax or Ativan). Long-term use of these drugs can lead to dependence and other risks. The study enrolled 170 veterans who had been taking ben…

This study tested whether a digital program called Sleepio, which provides cognitive behavioural therapy for insomnia, could be used by people with mild cognitive impairment or mild dementia. Thirty participants were enrolled to see if the program was acceptable and easy to use. …

This study tested a new sleep medication called daridorexant in 164 adults and elderly people with insomnia. Participants received either the drug or a placebo for 4 weeks. Researchers measured changes in total sleep time, how fast they fell asleep, and time awake after sleep ons…

This pilot study tested a program called Sleep-SMART for veterans aged 60 and older who have both mild cognitive impairment (MCI) and insomnia. The program combines standard insomnia therapy with memory-support strategies to help participants learn and stick with the treatment. R…

This small pilot study tested whether cannabis oil (with different ratios of CBD to THC) could help with insomnia in people who also have major depression. Fourteen adults took either a high-CBD oil, a low-CBD oil, or a placebo for a short time. The main goal was to see if a larg…

This study looked at whether teaching people with type 2 diabetes about good sleep habits can improve their sleep quality and blood sugar control. One hundred adults with type 2 diabetes and poor sleep took part. Half received sleep hygiene education and kept a sleep diary for tw…

This completed VA study tested two ways to help more veterans with chronic insomnia get brief behavioral treatment (BBTI) in primary care clinics. Over 277,000 veterans were included across four VA medical centers. The study compared training providers alone versus training plus …

This study tested whether an 8-week mindfulness-based stress reduction program could lower stress, anxiety, depression, and cortisol levels in infertile women. 84 women participated, with half taking the program and half serving as a control group. The goal was to see if mindfuln…

This study tested whether a culturally adapted version of cognitive behavioral therapy for insomnia (CBTi) could help Arab adults sleep better. 54 participants were randomly assigned to receive one of two adapted therapy versions or be placed on a waitlist. The goal was to see if…

This study tested whether a self-applied ear massage, done twice daily for two weeks, could improve sleep quality in 60 women affected by the earthquake in Hatay. Participants used a sleep tracker and filled out questionnaires to measure changes. The goal was to see if this simpl…

This study looked at whether teaching healthy habits to pregnant women could improve their sleep and physical activity. Fifty-seven women in their third trimester took part. One group received six weeks of health training, while the other group had standard care. Results showed t…

This study tested whether an internet-based cognitive-behavioral therapy program (iCBT-I) can help people with chronic insomnia. 107 adults were randomly assigned to receive the online program or usual care. The program included educational videos, sleep tracking, and techniques …

This study tested an online insomnia treatment program for adult survivors of childhood cancer. Over 1,500 survivors participated, using a web-based program that teaches healthy sleep habits and cognitive behavioral techniques. The goal was to see if improving sleep could also bo…

This study tested whether taking a 15-20 minute power nap each day for six weeks could improve sleep quality, reduce depression symptoms, and lower stress in healthy workers. Forty volunteers, including both daytime and shift workers, participated. Researchers measured changes us…

This study tested whether laughter yoga—a practice combining laughing exercises and breathing techniques—can reduce fatigue, improve sleep quality, and boost psychological well-being in people with multiple sclerosis. Forty MS patients participated, with one group doing laughter …

This 12-week study tested whether combining acupuncture, yoga, and gradual medication reduction can help adults aged 65 and older lower their use of benzodiazepines (medications for anxiety and insomnia). Twenty-three participants received weekly acupuncture, private yoga classes…

This study tested whether elastic therapeutic taping can reduce pain after open-heart surgery (CABG). 195 patients were randomly assigned to receive real tape, placebo tape, or another supportive treatment near the surgical site. Neither patients nor researchers knew who got whic…

This study tested a six-month exercise program that combines acupunch moves with SPOZ technology in 142 older adults with dementia. The goal was to see if it could improve balance, strength, and daily living skills. Participants did the program at adult daycare centers, and resea…

This study tested a mobile app called SleepFix that provides digital behavioral therapy for insomnia in 128 older adults aged 50+ who also had mild memory concerns. Participants either used the app or received online sleep health education. The goal was to see if the app could re…

This study tested a smartphone app that teaches older adults (60+) simple behavioral tricks to fall asleep faster and stay asleep longer. 270 participants used either the app or received online sleep tips. The goal was to see if the app could reduce insomnia symptoms more effecti…

This study tested whether acupressure—a gentle finger-pressure technique on specific body points—could improve sleep in elderly people living in care homes. 75 residents took part, with half receiving 12 acupressure sessions over four weeks. The results showed that those who rece…

This study tested whether an 8-week sleep coaching program delivered through a smartphone app is practical and acceptable for cancer survivors and their bedroom partners. Forty participants were enrolled to see if they would stick with the program and find it helpful. The goal wa…

This study tested whether reflexology (a type of foot massage) could reduce pain, improve sleep, and stabilize vital signs in 70 stroke patients. Half received reflexology twice a week for six weeks plus standard care, while the other half got standard care alone. The results are…

This study looked at whether doing tai chi for 24 weeks can improve sleep in college students with insomnia. 90 students were split into three groups: tai chi, brisk walking, or no exercise. The researchers measured sleep quality using a standard questionnaire and also checked le…

This study tested an online program called ALDER that teaches older adults skills to boost positive emotions and reduce anxiety. 33 people aged 65 and older who used benzodiazepines (anti-anxiety or sleep medications) at least twice a week took part. Over 5 weeks, they learned an…

This pilot study tested whether a 4-week online sleep therapy program (CBT for insomnia) could help breast cancer survivors take their daily hormone-blocking pills more regularly. 35 women with insomnia who sometimes missed their medication took part. The goal was to see if impro…

This study tested a culturally adapted internet-based cognitive behavioral therapy (iCBT) program for Arabic-speaking refugee and migrant youth aged 15–29 with mild to moderate mental health problems like depression, anxiety, and insomnia. 125 participants were randomly assigned …

This study looked at whether a six-week home program combining music with progressive muscle relaxation could improve sleep, fatigue, emotional symptoms, and quality of life in 20 sedentary obese women. Participants did the exercises on their own using phone apps. The goal was to…

This study looked at whether smelling geranium essential oil can help reduce tiredness and improve sleep in people receiving dialysis for kidney failure. 90 adults on dialysis took part in a crossover trial where they received both the aromatherapy and a placebo at different time…

This study tested whether a short lesson on good sleep habits could improve sleep quality and blood pressure in adults with high blood pressure. 138 people took part, with half receiving the lesson and a sleep diary, and the other half getting usual care. After 8 weeks, researche…

This study tested whether giving a combination of two sedative drugs (dexmedetomidine and esketamine) at night can improve sleep quality for ICU patients who need a breathing tube or high-flow oxygen mask. The trial involved 174 adults aged 50 and older after surgery. Researchers…

This study tested a mobile app called SleepFix that helps people with chronic low back pain and insomnia improve their sleep. Over 100 adults used either the app or received sleep education for 3 weeks. The goal was to see if better sleep could reduce how much pain interferes wit…

This study tested whether special light devices can improve sleep in 60 adults aged 60 and older who have had insomnia for at least 3 months. Participants used bright light, near-infrared light, or both for three weeks. Researchers measured sleep quality, daytime sleepiness, and …

This study tested whether sleep hygiene education plus motivational interviewing can improve sleep and quality of life in people on hemodialysis. Forty patients were split into two groups: one received face-to-face sleep training plus four online motivational sessions over six we…

This study tested an online sleep program for preschool-aged children with autism who have trouble sleeping. 20 children participated to see if the program was easy to use and helped improve sleep. The goal was to make sleep help more accessible for families.

This study tested whether showing fetal images to high-risk pregnant women could lower their stress and improve sleep quality. Seventy hospitalized women were randomly assigned to either view fetal images three times a day for two days or receive no intervention. Researchers meas…

This study tested whether a melatonin skin patch can improve sleep quality in 60 patients who had urological surgery. Patients wore a patch that slowly released melatonin to help regulate their sleep cycle. The goal was to see if this simple approach could reduce sleep problems c…

This study tested whether a simple mandala coloring activity could reduce anxiety, fatigue, and improve sleep quality in people aged 65 and older living in nursing homes. Over 8 weeks, participants colored mandala patterns for 1-2 hours each week. The study measured changes using…

This study tested a special sleep program for new parents and their babies. The program included sleep education, relaxation training, and support. Researchers wanted to see if it could improve sleep, mental health, and infant health. The study involved 306 parents and their newb…

This study tested a program to improve sleep and daytime activity in frail adults aged 65 and older with insomnia. Seven participants tried a 24-hour approach to build healthier sleep-wake habits. The goal was to see if the program was practical and well-liked, and to measure cha…

This study looked at whether a non-invasive brain training method called neurofeedback can help veterans who have had a mild traumatic brain injury and still suffer from chronic headaches, trouble sleeping, and attention problems. 87 veterans were randomly assigned to receive neu…

This study tested suvorexant (Belsomra), an FDA-approved sleep medication, in 40 older adults with insomnia. Participants took the drug or a placebo for two weeks while wearing a motion tracker and completing smartphone surveys about their sleep, mood, and thinking. The goal was …

This study tested a sleep and circadian treatment (TranS-C) for people with severe mental illness (SMI) in community mental health centers. The treatment was adapted to better fit these settings. Researchers looked at whether it improved sleep, daily functioning, and symptoms in …

This study tested whether the sleep medication suvorexant (Belsomra) can help older adults sleep better and reduce confusion after heart surgery. One hundred patients aged 60 and older received either suvorexant or a placebo for seven nights in the ICU. Researchers measured sleep…

This study tested whether adding the sleep medication eszopiclone (Lunesta) to brief behavioral therapy improves sleep quality and CPAP use in veterans with PTSD and complex insomnia. Fifty-three veterans who had trouble sticking with CPAP therapy for sleep apnea took part. The g…

This study tested whether a new drug called tasipimidine can help people with insomnia fall asleep faster and stay asleep longer. 190 adults with chronic insomnia took either the drug or a placebo for 3 nights in a sleep clinic, with some continuing for 4 more weeks at home. Rese…

This study tested two versions of a sleep treatment for people with severe mental illness in community mental health centers. One version was the standard treatment, and the other was adapted to better fit patients' needs. The goal was to see if training clinic staff to deliver t…

This study tested whether a sleep therapy called CBT-I could reduce depression and anxiety by improving how the brain controls emotions. 51 adults with poor sleep and depression symptoms took part. They met with a psychologist weekly for six weeks to learn better sleep habits. Th…

This study tested whether using a stress ball can reduce pain, improve sleep quality, and stabilize vital signs in critically ill patients in the intensive care unit (ICU). Sixty adult patients who were awake and able to communicate were randomly assigned to use a stress ball or …

This study tested a type of talk therapy called Cognitive Behavioral Therapy for Insomnia (CBT-I) in 70 people with brain tumors who also had trouble sleeping. The therapy involved six weekly group sessions delivered online. The main goal was to see if the approach was practical …

This study tested whether cognitive behavioral therapy for insomnia (CBT-I) can improve sleep and reduce pain in women with fibromyalgia. 131 women with both conditions received either CBT-I or sleep hygiene education. Researchers measured sleep quality, pain sensitivity, and bra…

This study tests whether shining low-level laser or LED light on specific acupoints on the hand can help people relax and improve sleep and anxiety. Researchers will measure heart rate and energy levels in 60 healthy volunteers before and after light therapy. The goal is to see i…

This study tested a personalized brain stimulation technique for people with insomnia. Twenty adults received 10 days of treatment, and researchers measured sleep quality and mood changes. The goal was to see if this approach could ease insomnia symptoms.

This study tested whether an 8-week mindfulness-based stress reduction program could improve quality of life, sleep, and mental well-being in menopausal women. Researchers enrolled 86 women aged 45-64 who had not had a period for at least a year. Half took the mindfulness program…

This study tested a powdered sleep supplement called BEAM Dream Powder in 40 adults who had trouble sleeping. For two weeks, participants took a placebo, then switched to the real powder for four weeks. Researchers used sleep questionnaires and Fitbit trackers to see if the powde…

This study tested whether sleeping with lavender sachets inside pillows for two weeks could improve sleep quality and reduce insomnia severity in 68 adults diagnosed with psychophysiological insomnia. Participants also kept a sleep diary and received sleep hygiene education. The …

This study tested a new 8-session psychotherapy called ChronoS in 67 adults with mood disorders (bipolar or depression) and chronic insomnia. The therapy focuses on sleep-wake awareness and habits. Researchers measured changes in insomnia severity using a standard questionnaire. …

This study looked at 57 university students with insomnia and compared two 8-week programs: mindfulness-based stress reduction (MBSR) and cognitive behavioral therapy for insomnia (CBT-I). Researchers measured how each program affected sleep quality, stress, anxiety, and mood. Th…

This study looked at whether giving first-time mothers continuous support from a midwife, starting at 36 weeks of pregnancy through the early weeks after birth, could improve their comfort, sleep quality, and confidence in breastfeeding. 128 women took part, with some receiving e…

This study tested a capsule containing cannabidiol (CBD) and terpenes to see if it improves sleep quality in people with chronic insomnia. 125 adults with insomnia took either the CBD capsule or a placebo for a period, and their sleep was tracked with a wrist device. The goal was…

This study tested whether a voice-activated virtual assistant (VAVA) could help young adult cancer survivors (ages 18–29) with chronic insomnia. The device delivers cognitive behavioral therapy for insomnia (CBT-I) through simple voice interactions. Fifteen participants used the …

This study tested whether taking Montmorency cherry supplements could improve sleep and reduce inflammation in adults with sleep problems and higher body weight. Thirty-four participants took either the cherry supplement or a placebo for a period of time. Researchers measured sle…

This study tested whether daily omega-3 supplements (fish oil) can help reduce stress, anxiety, depression, and improve memory and sleep in 64 Saudi adults who reported high stress. Participants took either omega-3 or a placebo for three months. Those taking omega-3 reported lowe…

This study tested a new mindfulness-based therapy called ACTCOM-I against standard cognitive behavioral therapy (CBT) for chronic insomnia in 31 adults. The new therapy focuses on acceptance and self-compassion to improve sleep. Researchers measured changes in insomnia severity a…

This study looked at whether breathing exercises can reduce pain, anxiety, shortness of breath, and trouble sleeping in people who had lung surgery. 74 patients who had VATS or wedge resection were taught a special breathing technique. Researchers measured their pain, anxiety, br…

This study tested whether yoga-based breathing exercises can reduce pain, fatigue, and insomnia and improve self-efficacy in people recovering from colorectal cancer surgery. 80 patients were split into two groups: one did the breathing exercises twice daily for about 20 minutes,…

This study tested a device called Cereset Research that plays tones in response to a person's brainwaves, aiming to reduce stress and improve sleep. 94 stressed healthcare workers used the device for several sessions and were followed for a year. The goal was to see if the device…

Researchers are studying whether daily step counts and other smartwatch measurements can predict which cancer patients will be readmitted to the hospital after discharge. Adults who have just left an oncology ward wear a Huawei smartwatch for 30 days to track steps, heart rate, a…

This study aims to translate and validate a French version of the Sleep Regularity Questionnaire (SRQ), a tool that measures how consistent a person's sleep schedule is. Researchers will enroll 50 adults with chronic insomnia or circadian rhythm disorders, who will fill out the q…

Researchers at the University of Pavia are studying whether long-term exposure to urban air pollution and work-related stress affects biological aging. The study compares 151 adult workers in Pavia, Italy: outdoor workers such as police officers, taxi drivers and dustmen, and ind…

This trial tests whether a mobile exercise app can deliver the same benefits as supervised training. Healthy university students will be randomly assigned to use the 7-Minute Workout® app, follow a supervised high-intensity interval training program, or receive no intervention fo…

This study looks at what influences sleep quality in patients recovering in the intensive care unit after open-heart surgery. Researchers will measure pain, fatigue, and environmental stressors to see which factors most affect sleep. The goal is to find ways to improve sleep and …

This completed pilot study in Yomitan Village, Okinawa tested three simple, low-cost approaches to reduce stress and encourage healthy habits in 45 adults with overweight or pre-metabolic syndrome. Participants were randomly assigned to receive health leaflets, wear functional cl…

This study looks at pain, sleep quality, eating habits, and physical activity in 50 adults with bipolar disorder who are currently stable (euthymic). Researchers will use questionnaires to measure these factors and better understand how they affect quality of life. The goal is to…

This study tests whether a very short sleep survey, called the Sleep Vital Sign, can help primary care doctors recognize sleep disorders like sleep apnea, insomnia, and restless leg syndrome. About 1,260 adults visiting their Kaiser Permanente doctor will fill out the survey, whi…

This study looks at how well university athletes sense their own body signals (like heartbeat or tension), their stress levels, anxiety, and sleep quality, and how these relate to physical tests like grip strength, jump height, flexibility, and balance. Researchers also check if …

This study looks at 135 preschool children aged 3 to 6 to see if being raised by relatives, caregivers, or in daycare affects their development, sensory processing, and sleep. Researchers will use standard tests to measure these areas and compare results across different caregivi…

This study looks at how good or poor sleep quality influences quality of life, depression, and fatigue in people with multiple sclerosis. Researchers will survey about 121 adults with MS to measure their sleep patterns and link them to these health outcomes. The goal is to better…

This study examines whether ticagrelor, a heart medication, changes how the body absorbs and processes YZJ-1139, an experimental insomnia treatment. Healthy volunteers aged 18 to 45 will take YZJ-1139 alone and then with ticagrelor to compare drug levels and safety. The goal is t…

This study examines whether a new insomnia drug, YZJ-1139, can be safely taken with the antidepressant escitalopram. Healthy adults aged 18 to 45 will receive both drugs and be monitored for side effects, drug levels in the blood, and changes in eye movements, balance, and thinki…

This study examines how the sleep aid YZJ-1139 behaves in people with severe kidney impairment compared to those with normal kidney function. Sixteen adults will receive a single 20 mg dose, and researchers will measure drug levels in the blood and urine, as well as any side effe…

This study surveys anesthesiologists to explore whether feelings of being a fraud (impostor phenomenon) are linked to everyday memory and attention lapses. Participants complete online questionnaires about impostor feelings, cognitive failures, anxiety, depression, sleep quality,…

This study looked at 69 people with Parkinson's disease to see if sleep quality is linked to thinking skills and disease severity. Participants completed tests of sleep, memory, attention, and movement in one session. The goal is to better understand how these factors relate, whi…

This completed study looked at 1,740 newly married couples to see if the bacteria in their mouth, eyes, and gut are linked to sleep problems, vision issues, and mood. Participants provided samples and completed surveys about sleep, anxiety, depression, and dry eye symptoms. The g…

This study looked at 62 children with cerebral palsy (ages 2-18) and their primary caregivers to understand how the children's sleep problems relate to caregiver burden and mental health. Researchers used questionnaires to measure sleep quality in both children and caregivers, al…

This study looked at 194 university students aged 18-30 to see how smartphone and digital game addiction relates to physical activity, sleep quality, stress, fatigue, and muscle or joint pain. Participants filled out questionnaires about their habits and health. The goal is to un…

This study looks at how stress and insomnia are connected. Researchers used driving simulations with stressful events to measure emotional reactions and sleep patterns in 15 women with and without insomnia. The goal is to understand how stress affects sleep and vice versa, which …

This study looked at 48 young adults (24 with bruxism, or teeth grinding, and 24 without) to understand how jaw function, posture, muscle stiffness, pain, stress, and sleep quality are connected. Researchers used special tools to measure posture, muscle tightness, and pain levels…

This study looked at whether veterans with traumatic brain injury (TBI) and insomnia can reliably measure their internal body clock at home. Thirty-one veterans wore a wrist device for a week and collected saliva samples to track melatonin levels. The goal was to see if these hom…

This study looked at whether using a wearable device (like a fitness tracker) along with social media can help adults become more active and sleep better. 75 adults who had never used a wearable device before took part. The researchers measured changes in physical activity and sl…

This study followed 42 sprinters to see if doing plyometric exercises (like jumps) at least twice a week during winter preseason improved their race times and reduced leg injuries. Participants reported their best times and any health problems online. The goal is to understand if…

This study looked at 198 adults with non-metastatic gastrointestinal cancer to see if taking chemotherapy as a pill (oral) or through a vein (IV) affects sleep quality and depression. Researchers measured sleep and mood before treatment, at 45 days, and at 90 days using standard …

This study looked at whether regular outdoor horseback riding can improve leg strength, core stability, balance, sleep, and overall function in healthy adults. Researchers compared 64 people who rode horses outdoors at least once a week for six months with non-riders. They measur…

This study tested a computer system designed to help doctors more accurately diagnose and manage complex brain disorders like dementia, epilepsy, and sleep problems. Researchers collected health data from 635 people visiting specialty clinics, including healthy volunteers, to see…

This study looked at how often insomnia occurs in people hospitalized for psychiatric conditions. Researchers checked 427 patients at 11 hospitals in Switzerland and Germany. They also explored whether age, gender, or type of disorder made insomnia more likely.

This study looked at 102 people with multiple sclerosis to see how sleep quality relates to fatigue, body awareness, and arm and leg function. Participants were grouped by good or poor sleep, and their abilities were measured with tests like walking speed and a heartbeat counting…

This study looked at whether treating insomnia can reduce the risk of heart disease in people with PTSD. Researchers measured blood pressure, blood vessel health, and other heart risk factors in 140 adults aged 40-59. The goal was to see if improving sleep could also improve hear…

This study looked at 138 physical therapy students aged 18-30 to see if their eating habits, sleep quality, and stress levels are linked. Participants filled out three questionnaires about eating attitudes, sleep, and perceived stress. The goal was to understand how these factors…

This study followed 18 adults with active ankylosing spondylitis who were starting anti-TNF therapy for the first time. Researchers measured their sleep quality using overnight sleep tests and a questionnaire, and tracked their daily step counts with a wearable device. The goal w…

This study looked at 149 adults with high blood pressure and insomnia to understand how poor sleep might raise the risk of heart disease. Researchers used a sleep therapy called CBT-I to see if improving sleep could lower nighttime blood pressure. The goal was to learn more about…

This study watched 225 people with solid tumors who got a drug called G-CSF during chemotherapy. G-CSF can cause bone pain. Researchers measured pain levels and tracked what treatments (like pain relievers or other methods) helped. They also checked quality of life, fatigue, mood…

This study looked at 120 university students to see if their smartwatch step counts matched what they reported on a physical activity questionnaire. Participants wore an Apple Watch and filled out a short survey about their weekly activity. The goal was to understand if objective…

This study looked at whether insomnia affects pain sensitivity in people with Irritable Bowel Syndrome (IBS). Researchers measured pain thresholds using a barostat procedure in 70 participants, including IBS patients with and without insomnia, healthy volunteers, and people with …

This study tested whether a structured nutrition education program could improve nursing students' nutrition knowledge, eating habits, physical activity, and sleep quality. Forty-two students took part in multiple educational sessions. Researchers measured changes right after the…

This study looked at how well smartphone apps and a special ring (Belun Ring) can measure sleep quality in adults getting braces or other orthodontic treatment. 52 people from Case Western Reserve University's dental clinic took part. They answered sleep questionnaires and used t…

This completed study looked at how blood sugar levels affect sleep in 30 adults with cystic fibrosis-related diabetes. Participants wore devices at home to track glucose and sleep for 10 days. The goal was to see if this kind of remote monitoring is practical and to gather early …

This study looked at 74 physiotherapy students to see how their daily physical workload—like time spent sitting and standing—affects their posture. Researchers used a 3D back scanner and surveys to measure posture, activity levels, sleep, and burnout. The goal was to find risk fa…

This study looked at 102 adults to see how common restless legs syndrome is in people with temporomandibular joint (jaw) disorders. Researchers also checked if having both conditions affects sleep quality and daily life. Participants filled out questionnaires about their symptoms…

This completed study compared 72 adults with cervicogenic headache (headache from the neck) to healthy volunteers. Researchers used questionnaires to measure central sensitization (overactive pain signaling) and neuropathic pain (nerve pain). The goal was to see if these pain mec…

This study followed 127 first-time mothers to see if their sleep quality, anxiety levels, and nighttime phone use before labor were linked to how long labor lasted and whether they needed extra medical help. Participants filled out questionnaires during routine checkups, and rese…

This completed study looked at how common poor sleep is after a C-section when spinal morphine is used for pain relief. Researchers followed 286 mothers and measured sleep quality, pain, nausea, and itching on the first night after surgery. The goal was to understand which factor…

This study looks at how cardiac arrest affects thinking, memory, emotions, and sleep over time. About 200 survivors will take detailed brain tests 7 and 24 months after their cardiac arrest. Their results will be compared to heart attack patients who did not have a cardiac arrest…

This study looked at whether people with bruxism (teeth grinding or clenching) have worse lung function, breathing muscle strength, balance, and sleep quality compared to healthy people. Researchers tested 34 adults using breathing tests, balance assessments, and sleep questionna…

This study examined 86 professional e-athletes aged 18-35 to understand what factors are linked to pain, fatigue, and poor sleep quality. Researchers assessed pain severity, fatigue levels, sleep quality, and physical activity. The goal is to identify health risks in esports and …

This study followed 2,365 adults from urban areas of Chile for 12 months to learn more about chronic pain and its effects. Researchers looked at how chronic pain relates to mental health issues like depression and anxiety, as well as work stress and daily functioning. The goal wa…

This study used a wearable ring and sleep diaries to track sleep patterns in 18 healthy older adults over six weeks. Researchers also tested their balance and thinking skills to see how these factors relate. The goal was to better understand how sleep affects mobility and brain f…

This study tested different parts of a common insomnia treatment (CBT-I) to see which ones work best alone or together. 489 adults with chronic insomnia took part online. The goal was to find the most effective combination for future use.

This study looked at how to help busy doctors at VA clinics adopt better treatments for three common issues: reducing risky medications in older adults, using blood thinners more safely, and offering talk therapy for insomnia instead of sleep pills. Researchers compared two diffe…

This study looked at 48 adults with mood disorders and insomnia to see if a strong relationship with their therapist helped them get better results from a new type of therapy called ChronoS. The therapy combines sleep scheduling, mindfulness, and stress management. Researchers me…

This study looks at how disrupted sleep changes the way common drugs (like painkillers, stimulants, and sedatives) work in the body. Researchers will disturb the sleep of 148 healthy adults in a lab and then measure how their brains respond to these drugs, including pain relief a…

This completed study looked at 171 people with HIV to see if insomnia makes pain worse and increases inflammation. Participants wore sleep trackers, kept sleep diaries, and underwent pain tests. The goal was to understand if poor sleep drives pain and inflammation, which could ma…

This study looked at whether the way a child's jaw is aligned (called skeletal malocclusion) affects their sleep quality. Researchers studied 164 children aged 7 to 13 who had no other mouth or breathing problems. They measured sleep using a parent questionnaire and took X-rays t…