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Nighttime dialysis matches daytime in cleaning blood, study finds

NCT ID NCT05449067

Disease control Sponsor: Nanfang Hospital, Southern Medical University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared two types of home dialysis for people with end-stage kidney disease: nighttime automated dialysis (APD) and daytime manual dialysis (CAPD). 137 non-diabetic adults tried each method for 12 weeks. The goal was to see if nighttime dialysis was as good as daytime dialysis at removing waste from the blood. The study also looked at sleep quality, daily life, and blood pressure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

137 people

The number who actually took part.

Started

May 2022

Finished

Feb 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age 18 to 75 years; 2. Maintenance peritoneal dialysis for ≥ 1 month; 3. Weekly total CrCl ≥ 45 liters/week/1.73m2 body surface area; 4. Total weekly Kt/V ≥ 1.7. Exclusion Criteria: 1. Patients with diabetes mellitus; 2. Maintained peritoneal dialysis solution with a glucose concentration \>2.5%; 3. Combined with acute events of cardiovascular disease(CVD), cardiac function ≥ New York Heart Association (NYHA) class III; 4. Episodes of peritonitis in the past 1 month; 5. Abdominal surgery other than PD catheter insertion in the past 3 months; 6. Planned kidney transplant in the last 6 months; 7. Active hepatitis, cirrhosis, psychiatric disease, malignancy, pregnancy.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease end stage renal failure insomnia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

End-stage kidney disease Peritoneal dialysis

Contacts and locations

Locations

  • Nanfang Hospital of Southern Medical University

    Guangzhou, Guangdong, 510015, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.