Nanfang Hospital, Southern Medical University

This study tests a special plate that dissolves over time to support the skull base after pituitary tumor removal. The goal is to see if it reduces spinal fluid leaks and infections after surgery. About 126 people having this type of brain surgery will take part.

This study tests a drug called anlotinib in 57 adults with a rare brain tumor (craniopharyngioma) that has returned after surgery. The main goal is to see if the drug can shrink the tumor. Researchers will also track how long the tumor stays controlled and monitor side effects. T…

This study tests if combining PRP (platelet-rich plasma) with Botox injections works better than PRP alone for treating androgenetic alopecia (male/female pattern baldness). About 76 adults aged 18-60 with mild to moderate hair loss will receive monthly scalp injections for three…

This study tests a combination of two immunotherapy drugs (iparomlimab and tuvonralimab, together called QL1706), a targeted therapy (bevacizumab), and chemotherapy given directly into the liver artery for people with advanced liver cancer that has spread into the main portal vei…

This study tests a new treatment for people with advanced or recurrent esophageal cancer that cannot be removed by surgery. It combines standard chemoradiotherapy with an immunotherapy drug called adebrelimab. The goal is to see if this combination can shrink tumors and improve s…

This study tests two different dental repairs for large holes in teeth after root canal treatment. About 246 people with treated premolars will get either a modified endocrown or a post and crown. Researchers will check how well each repair holds up over two years using X-rays an…

This study tests a new fluorescent dye that targets cancer cells to help doctors see which lymph nodes contain cancer during stomach cancer surgery. About 47 people with early stomach cancer will have their removed lymph nodes examined with this probe. The goal is to avoid removi…

This study is testing a computer program that learns from thousands of tissue samples to help pathologists diagnose cancer. The goal is to make diagnoses faster and more accurate, and to help guide treatment decisions. The study will include 2,000 adults with various cancers who …

This study tests a new way to create detailed 3D images of lung and colorectal cancer tissue. Researchers will use a special preprocessing system and staining technique to get clearer pictures than standard 2D methods. The goal is to help doctors diagnose cancer more accurately a…

This study compares a new ultrasound-guided procedure (EUS-SVD) to the standard glue injection for preventing re-bleeding of enlarged veins in the stomach. About 84 adults with high-risk stomach varices will be randomly assigned to one of the two treatments. The goal is to see wh…

This study looks at two sedatives, ciprofol and propofol, for ICU patients who need help breathing but are not on a ventilator. The goal is to see which drug works better and has fewer side effects like breathing problems. About 1,680 adults from 30 hospitals in China will be inc…

This study looks at whether a patient's emotional state—like depression or anxiety—can influence how well advanced liver cancer responds to a combination of chemotherapy, targeted therapy, and immunotherapy. Researchers will follow 90 adults with BCLC stage B or C liver cancer, g…

This study looks at liver tissue and blood from 240 people with various liver conditions, including fatty liver, hepatitis B, fibrosis, and cirrhosis. Researchers will use cutting-edge technology to study individual cells and their surroundings. The goal is to better understand h…

This study looks at whether a non-invasive intestinal ultrasound can predict when Crohn's disease will come back in patients who are currently in deep remission. Researchers will follow 420 adults for 18 months to see who relapses and compare ultrasound results between those who …

This study looks at 3,000 people with type 2 diabetes to see if signs of inflammation in the blood are linked to diabetes-related health problems. The goal is to find early clues that could help doctors identify who is at higher risk. No new treatments are being tested—just measu…

This study looks back at medical records of 1,500 ICU patients with sepsis and low platelet counts to see if platelet transfusions help them survive 28 days. It also checks for bleeding and blood clots. The goal is to learn whether this common treatment actually helps or harms, s…

This study follows 400 adults with early colorectal cancer whose endoscopic removal was not fully successful (non-curative). Researchers will compare outcomes between those who have additional surgery and those who are simply monitored. The goal is to find better ways to manage t…

This study looks at how the immune system's germinal centers—special areas where immune cells learn to fight infections—work in people with chronic hepatitis B. Researchers will collect blood and tissue samples from 280 patients having surgery to study the immune cells and their …

This study looks at why people with chronic kidney disease (CKD) often lose muscle mass and strength, a condition called sarcopenia. Researchers will follow 1,000 adults with CKD to find risk factors for sarcopenia and see how it relates to worse health outcomes like disease prog…

This study looks at how common sleep apnea is in people with chronic kidney disease and whether it makes their kidney function worse over time. Researchers will follow 356 adults with moderate kidney disease for several years, tracking their health and any heart or kidney problem…

This study follows 800 adults with type 2 diabetes to see how their lifestyle choices relate to long-term complications like heart or kidney problems. Researchers will track participants over time to find patterns that could help identify high-risk individuals early. The goal is …

This observational study follows 5,000 untreated chronic hepatitis B patients aged 1 to 80 for years. Researchers will test blood every six months to see how the immune system changes as the disease progresses. The goal is to better understand the natural history of HBV infection…