Nanfang Hospital, Southern Medical University

This study tests if a drug called edaravone dexborneol can help people who have both a stroke and active cancer recover better. About 144 adults will get either the drug or standard care, and doctors will check their recovery and safety for 30 days. The goal is to find a safer, m…

This study tests whether a new drug called gecacitinib, combined with standard therapy, can prevent acute graft-versus-host disease (aGVHD) in people with myelofibrosis who receive a stem cell transplant. About 40 adults will take part. The goal is to see if the drug reduces seve…

This study tests whether the drug luspatercept can prevent severe anemia (low red blood cells) after a stem cell transplant in people with blood cancers who also have moderate to severe myelofibrosis (scarring in the bone marrow). About 196 adults aged 18-65 will be randomly assi…

This study tests whether the drug butylphthalide can reduce brain swelling and improve recovery in people who had a major stroke and underwent a procedure to reopen a blocked artery. About 100 adults will receive either the drug or a placebo. The goal is to see if the drug helps …

This study looks at 2000 people who had a stroke to see which blood thinner (indobufen, aspirin, cilostazol, or clopidogrel) works best to prevent another stroke and has the fewest side effects like bleeding. Researchers will track patients for one year after treatment. The goal …

This study looks at whether adding beta-blockers (a type of blood pressure medicine) to standard immunotherapy before surgery can help shrink tumors in people with locally advanced stomach cancer who also have high blood pressure. About 33 participants will receive the combinatio…

This study tests a combination of two drugs (Benmelstobart and Anlotinib) plus targeted radiation (SBRT) in 29 adults with liver cancer that has spread to a few spots and stopped responding to initial therapy. The goal is to see if this triple approach can slow or stop cancer gro…

This study tests whether combining sorafenib and venetoclax can eliminate tiny amounts of leukemia that remain after initial treatment (called measurable residual disease, or MRD). About 87 adults with acute myeloid leukemia (AML) will receive this drug pair. The goal is to see i…

This study tests whether adding inhaled nitric oxide (iNO) to standard care can help adults with moderate-to-severe acute respiratory distress syndrome (ARDS) live longer. About 536 participants will be randomly assigned to receive iNO or a placebo through their ventilator. The m…

This study tests whether adding a traditional Chinese medicine formula (Fufang Biejiaruangan) to standard antiviral therapy can lower the chance of developing liver cancer in people with hepatitis B-related cirrhosis. About 1,034 high-risk adults (ages 18-65) will be randomly ass…

This study tests whether adding Babao Dan Capsule, a traditional Chinese medicine, to standard antiviral therapy can lower the chance of developing liver cancer in people with hepatitis B-related cirrhosis who are at high risk. About 1,034 participants will be randomly assigned t…

This study tests whether a 48-week course of pegylated interferon alfa-2b can help teens and children (ages 3-17) with chronic hepatitis B achieve a clinical cure. About 113 participants will either receive the drug or standard care (no drug or nucleoside analogs). The goal is to…

This study tests whether adding a PCSK9 inhibitor (a cholesterol-lowering drug) to standard care helps people recover better after a stroke caused by a blocked artery. About 478 adults with acute ischemic stroke who undergo endovascular therapy (a procedure to reopen the artery) …

This study tests whether adding a targeted drug (dalpiciclib) and hormone therapy to brain radiation can help control breast cancer that has spread to the brain. About 46 women with HR-positive, HER2-negative advanced breast cancer will receive the combination treatment. The goal…

This study tests a new fluorescent dye that makes stomach cancer cells glow, helping surgeons see exactly where the tumor ends during surgery. The dye is given to removed stomach tissue in a lab setup that mimics blood flow. Researchers will check if the dye's glow matches the ca…

This study tests a drug called nanocrystalline megestrol acetate to see if it can prevent weight loss and improve appetite in people with advanced liver cancer who are already receiving standard treatments. About 88 participants will be randomly assigned to receive either the dru…

This study tests whether a smartphone app powered by a large language model (like a smart chatbot) can improve the emotional well-being and quality of life of women with breast cancer. About 440 adult women with primary breast cancer will either use the app plus usual care or rec…

This study tests whether a computer-aided detection system can help doctors find more polyps in the right side of the colon during a colonoscopy. About 686 adults aged 40-75 will have two colonoscopies in one session, with the computer system used in one of them. The goal is to s…

This study tests whether artificial intelligence (AI) can help pathologists (doctors who diagnose diseases by looking at tissue samples) work better and faster. Over 2000 patients will have their tissue samples reviewed either with or without AI assistance. The goal is to see if …

This study watches how nutrition changes in children with brain tumors during radiation therapy and how it relates to their quality of life. About 93 children aged 5-18 will be followed. The goal is to create a nutrition plan and early warning system to help kids feel better duri…