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Neck headaches linked to nerve pain? new study investigates

NCT ID NCT07292181

Knowledge-focused Sponsor: Gulseren Demir Karakilic Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study compared 72 adults with cervicogenic headache (headache from the neck) to healthy volunteers. Researchers used questionnaires to measure central sensitization (overactive pain signaling) and neuropathic pain (nerve pain). The goal was to see if these pain mechanisms are more common in people with cervicogenic headache and how they relate to sleep, mood, and daily function.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If the findings confirm a link, this could help doctors better understand and diagnose nerve-related pain in cervicogenic headache.
What could go wrong
This is a small, completed observational study (72 people) that only measures symptoms via questionnaires, not a treatment trial. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

72 people

The number who actually took part.

Started

Jul 2025

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population included 106 adult patients with cervicogenic headache and 106 age- and sex-matched healthy controls. Patients were recruited from outpatient clinics of Physical Medicine and Rehabilitation and Neurology at Bozok University, Turkey. Healthy volunteers were selected from the community and hospital staff who met the eligibility criteria.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Eligibility Criteria Inclusion Criteria: * Adults aged 18 to 65 years * Patient group: Clinical diagnosis of cervicogenic headache according to the International Classification of Headache Disorders, 3rd edition (ICHD-3) criteria * Healthy control group: Age- and sex-matched individuals without cervicogenic headache or other chronic pain conditions * Adequate cognitive function and literacy to complete questionnaires * Voluntary participation with written informed consent Exclusion Criteria: * Age younger than 18 years or older than 65 years * Inability to communicate effectively * Illiteracy * Refusal to participate * Presence of systemic diseases including diabetes mellitus, hypothyroidism, chronic kidney disease, or malignancy * Neurological diseases associated with neuropathic pain * Rheumatologic diseases including rheumatoid arthritis, ankylosing spondylitis, or fibromyalgia * Withdrawal of consent or incomplete data during the study

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Conditions

The condition(s) this trial relates to.

headache disorder insomnia Neck Pain neuralgia Post-Traumatic Headache

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Central sensitization Cervicogenic headache Neuropathic pain

Contacts and locations

Locations

  • Yozgat Bozok University Faculty of Medicine, Department of Physical Medicine and Rehabilitation

    Yozgat, Yozgat, 66100, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.