Tart cherry supplement shows promise for better sleep and less inflammation
NCT ID NCT05700643
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested whether taking Montmorency cherry supplements could improve sleep and reduce inflammation in adults with sleep problems and higher body weight. Thirty-four participants took either the cherry supplement or a placebo for a period of time. Researchers measured sleep duration, quality, and insomnia symptoms, along with inflammatory markers in the blood.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Montmorency cherry supplement
- What this could lead to
- If it works, this could point toward a natural way to improve sleep and reduce inflammation.
- What could go wrong
- This is a small, early-phase study with only 34 participants, so results may not apply widely. The supplement may not outperform placebo.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 1/2
Runs two stages together: safety and dose first, then whether the treatment works.
- Participants
-
34 people
The number who actually took part.
- Started
-
Feb 2023
- Finished
-
Apr 2024
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 50 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * body mass index (BMI) of ≥ 25.0 kg/m2; * sleep issues as identified by a global score of 5 or greater on the Pittsburgh Sleep Quality Index (PSQI) and/or a score 8 or higher on the Insomnia Severity Index (ISI); * ability to adhere to a diet low in antioxidants during the study period; and * willingness to wear a Fitbit for the duration of the study and to wear the Zmachine on selected nights. Exclusion Criteria: * unwilling or unable to stop the use of sleep medication * unable to attend laboratory visits on the East Lansing, Michigan campus
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Michigan State University
East Lansing, Michigan, 48824, United States
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