HYPERTENSION

This study tested whether empagliflozin, a common diabetes drug, lowers blood pressure more than other oral diabetes medications in people with type 2 diabetes and high blood pressure. 300 adults were randomly assigned to one of two groups and followed for 12 weeks. The main goal…

This study tested a program where community health workers used a tablet app to screen pregnant women in rural India for anemia, high blood pressure, and diabetes. Women who screened positive were referred to a doctor for treatment. The goal was to see if this approach could redu…

This study tested whether a single pill containing three medicines (ezetimibe, rosuvastatin, and amlodipine) could safely lower both cholesterol and blood pressure in Korean adults with both conditions. 163 participants took either the triple-combination pill or a standard two-dr…

This study tested a new drug called SLx-2101 in 26 adults with moderate to severe high blood pressure. Participants took the drug or a placebo for 12 days to see how well it lowered blood pressure and if it was safe. The goal was to find the best dose for future studies.

This study tested whether a tighter blood pressure target (below 135/85 mmHg) is better than usual care (below 150/100 mmHg) for women who had high blood pressure during pregnancy. 61 women were enrolled and followed for 6 months after giving birth. The goal was to see if this ap…

This study tested whether using mobile monitoring devices along with nurse support can help people better manage type 2 diabetes and high blood pressure. 220 adults with poorly controlled diabetes and high blood pressure took part. Researchers measured changes in blood sugar and …

This study tested whether text messages could help homeless adults with uncontrolled high blood pressure lower their numbers. About 120 participants received either standard healthy lifestyle texts or extra texts focused on blood pressure control. Researchers measured changes in …

This study looked at whether a heart-healthy DASH diet, modified for people with type 2 diabetes, along with less salt, can lower blood pressure. 105 adults with diabetes and high blood pressure were given different diets for five weeks each. The goal was to see if the DASH diet …

This study tested an experimental drug called KBP-5074 in 162 people with moderate-to-severe chronic kidney disease whose high blood pressure was not well controlled. The goal was to see if the drug could safely lower blood pressure and reduce kidney damage. Participants were ran…

This study tested a program called ENHANCE to help people with two or more long-term health problems like HIV, high blood pressure, diabetes, asthma, or depression. Over 1,800 adults aged 40 and older took part. Some clinics used a special decision-support tool and home visits fr…

This study looked at whether a drug called bosentan could lower blood pressure in people with sleep apnea and mild hypertension, as well as the standard CPAP machine does. Nineteen participants were given either bosentan or CPAP to compare effects on daytime and nighttime blood p…

This study tested a program to help African American and Latinx patients with high blood pressure get their numbers under control. 445 participants used home blood pressure cuffs and received support to lower their readings below 130/80 mmHg. The goal was to reduce racial differe…

This study tested a low-cost method to help clinics in Mozambique better find and treat high blood pressure in people with HIV. The approach used regular check-ins and improvements by district health supervisors. The goal was to see if this could increase the number of patients w…

This study tested whether yoga can help African American adults with high blood pressure manage stress, remember to take their medication, and lower their blood pressure. Eight participants attended weekly yoga classes for 8 weeks. Researchers measured blood pressure, stress leve…

This study tested two ways of delivering exercise therapy to 31 adults with high blood pressure using digital technology. One group exercised with a physiotherapist guiding them live via video calls, while the other group followed pre-recorded exercise videos on their own. Over 8…

This study tested a new drug called zilebesiran in 663 adults whose high blood pressure was not well controlled by their current medicines. Participants took zilebesiran or a placebo alongside their usual blood pressure pills. The main goal was to see if zilebesiran could lower b…

This study tested whether remote blood pressure monitoring helps cancer patients on the drug bevacizumab better manage high blood pressure. Twenty adults used either a remote monitor or a paper log to track their blood pressure at home. The goal was to see if remote monitoring im…

This study looked at whether keeping blood pressure very well controlled could prevent bone damage (osteonecrosis) in children and young adults being treated for leukemia or lymphoma. 51 participants were randomly assigned to either intensive or standard blood pressure management…

This study looked at whether playing recreational beach tennis for 12 weeks could lower blood pressure and improve physical fitness in 42 adults with high blood pressure. Participants were randomly assigned to either a beach tennis program or a non-exercising control group. The m…

This study tested whether a digital program that includes personalized health coaching and a connected blood pressure cuff, all delivered via smartphone or website, can help people with high blood pressure get it under control. About 318 adults with hypertension from Stanford Pri…

This study tested a virtual health program for African immigrants aged 25-75 who are uninsured and have at least two risk factors like high blood pressure, prediabetes, or obesity. Participants used Bluetooth scales and blood pressure monitors to track their health over six month…

This study tested a single pill containing three medicines (telmisartan, amlodipine, and rosuvastatin) in 252 Korean adults with both high blood pressure and high cholesterol. After 8 weeks, the pill lowered blood pressure and LDL (bad) cholesterol. The goal was to see if combini…

This study looked at what prevents people with HIV in northern Tanzania from getting care for heart attacks. Researchers tested a program where community health workers provided counseling, doctor visits, and phone calls to help control high blood pressure. The goal was to see if…

This study looked at whether help from a significant other (like a family member or friend) can improve how well people with high blood pressure follow healthy habits and take their medication. 133 people with high blood pressure and their significant others took part. The signif…

This study tested a program called ENACTS to help Native Hawaiian and Pacific Islander adults with high blood pressure. The program focused on healthy eating, exercise, and family support. 182 people took part, and researchers measured changes in blood pressure and lifestyle habi…

This study tested whether a mild electrical stimulation on the ear (transcutaneous vagus nerve stimulation) could help control blood pressure in people undergoing heart stent surgery. 480 adults with coronary artery disease and high blood pressure took part. Half received the rea…

This study tested a comprehensive intelligent system (CHESS) to help manage high blood pressure in primary care clinics. Over 1,600 participants were involved, and the system aimed to lower blood pressure over 12 months. The approach uses technology to support doctors and patient…

This study tested whether a special diet made from tartary buckwheat can lower blood pressure in people with mild hypertension. Researchers think the diet works by restoring healthy gut bacteria. 130 adults with untreated high blood pressure took part, comparing the buckwheat die…

This study looked at whether community health workers can help low-income adults better manage chronic diseases like diabetes, high blood pressure, and obesity. About 200 people took part over 10 months. The goal was to see if working with a health worker improved health markers …

This study tested whether community health workers and home blood pressure monitors can help adults in rural South Africa better control their high blood pressure. 774 participants with high blood pressure were enrolled. The goal was to find the best way to lower blood pressure a…

This study tested a procedure called renal denervation, which uses energy to calm overactive nerves in the kidneys, to see if it can safely lower blood pressure in people whose hypertension is not controlled by up to three medications. The study involved 337 participants and meas…

This study tested if using the vagus nerve to guide robotic surgery for removing the spleen and disconnecting certain blood vessels could reduce digestive problems like diarrhea and slow stomach emptying. Sixty adults with cirrhosis, an enlarged spleen, and bleeding from high blo…

This study tested whether giving patients home blood pressure monitors and digital tools (like text messages and online portals) helps them better manage their high blood pressure. 540 adults in San Francisco took part. The goal was to see if these tools improve blood pressure co…

This study tested whether stroke patients with high blood pressure benefit from extra support from a nurse, including education and follow-up, compared to usual care. About 290 patients over 60 who had a first stroke and had high blood pressure took part. The main goal was to see…

This study tested two approaches—weight-focused (aiming for weight loss) and weight-neutral (focusing on physical activity without weight loss goals)—to improve metabolic health in Black adults with stage 1 obesity and related conditions like high blood pressure or prediabetes. F…

This study tested whether adding a very low-carbohydrate diet to a proven lifestyle program could help lower blood pressure in lower-income African American adults. About 64 participants were followed for 10 months. The goal was to see if this approach could reduce heart disease …

This study tested a 12-week food-as-medicine program for 159 adults who have high blood pressure and struggle to afford enough food. Researchers wanted to see if offering tailored food support could help lower blood pressure and improve diet. The program used either in-person or …

This study tested whether a peanut-based food supplement could improve nutrition and health in adults aged 60 and older. 81 participants were randomly assigned to either eat the supplement daily for 12 weeks or to continue their usual diet. Researchers measured weight, blood pres…

This study tested a new drug called zilebesiran in 375 adults with high cardiovascular risk and high blood pressure that standard medications couldn't control. Participants took zilebesiran or a placebo alongside their usual blood pressure pills. The goal was to see if zilebesira…

This study tested whether a combination of two blood pressure medicines (LCZ696 and amlodipine) works better than one medicine alone. It included 718 adults with mild to moderate hypertension that was not well controlled by LCZ696 alone. Participants received either the combo or …

This study looked at whether adding paced or diaphragmatic breathing to mat Pilates can improve heart and lung fitness, reduce shortness of breath, lower stress and anxiety, and boost quality of life in people with stage II hypertension. Sixty-three adults aged 40 to 50 took part…

This study tested a smartphone app called SMART-HABITS in 47 adults with chronic kidney disease and high blood pressure. The app provided reminders, feedback, and educational resources to help patients track their blood pressure and steps. The goal was to see if people would use …

This study looked at whether it is safe and helpful to reduce blood pressure medication in frail older adults living in long-term care. Over 500 residents with low blood pressure took part. In one group, doctors and pharmacists slowly lowered their blood pressure pills, while the…

This study looked at how 10 weeks of moderate versus intense exercise affects brain health, blood pressure, and eye blood vessels in 35 adults aged 35-65 with hypertension and a BMI of 25 or higher. Participants used smartphone apps to track workouts. The goal was to see if exerc…

This study looked at whether a special blood pressure cuff and monitoring program can help people with high blood pressure get better control when their doctor visits are virtual. About 100 adults with hypertension joined the study. The program tracked their blood pressure at hom…

This study tested a new way to manage high blood pressure and heart disease risk in people living with HIV in Botswana. Over 4,600 adults on HIV treatment joined the program, which added blood pressure checks and medication to their regular HIV clinic visits. The goal was to see …

This study tested whether community health workers can help adults with high blood pressure who also struggle to afford food. 75 participants received support to eat more fruits and vegetables and manage their blood pressure. The goal was to see if this approach is practical and …

This study tested a nurse-led program to help veterans with HIV better manage their blood pressure and reduce their risk of heart disease. About 305 veterans with HIV and high blood pressure took part. The program used video visits and care coordination to support healthy changes…

This study looked at whether visits from a parish nurse (a nurse from a church) can help people with high blood pressure lower their numbers. About 100 adults from church health fairs in Los Angeles took part. Half were assigned to see a parish nurse, and the other half went to t…

This study tested a new way to treat high blood pressure without pills. Doctors used focused ultrasound to modify fat around the kidney in 79 patients with mild hypertension who were not on medication. The goal was to see if this procedure could safely lower blood pressure compar…

This study looked at whether adding community health workers to regular care helps patients with type 2 diabetes and high blood pressure in rural Mexico. 168 adults took part. The goal was to see if their blood sugar and blood pressure improved and if they took their daily medici…

This study tested an experimental drug called ALN-AGT01 in 394 adults with mild-to-moderate high blood pressure. The goal was to see if it could safely lower blood pressure readings over 24 hours and in the doctor's office. Participants received either the drug or a placebo, and …

This study tested whether advanced practice nurses (APNs) could help people with high blood pressure get it under control. 483 adults with hypertension received either usual care or extra visits with an APN. The goal was to see if more patients could reach a healthy blood pressur…

This study tested whether adding a second drug (DWC202314) to an existing one (DWC202404) can lower blood pressure more effectively in people whose blood pressure remains high on just one medication. 192 adults with essential hypertension took part. The goal was to see if the com…

This study tested whether minocycline, an inexpensive antibiotic, can lower blood pressure in people whose hypertension does not respond to standard medications. Researchers gave 34 adults with resistant hypertension low or high doses of minocycline to see if it reduced daytime b…

This study tested whether a structured phone call from a medical student could help people with uncontrolled high blood pressure bring their home blood pressure logs to their doctor visits. 170 adults took part. The goal was to see if this simple outreach improves how well patien…

This study tested a daily pill called lorundrostat in 48 adults with moderate-to-severe obstructive sleep apnea and high blood pressure. The goal was to see if the drug could reduce breathing pauses during sleep and lower nighttime blood pressure. Participants took the drug or a …

This study tested an experimental pill called ralinepag for people with pulmonary arterial hypertension (PAH), a serious lung condition that makes the heart work too hard. About 687 adults with PAH took either ralinepag or a placebo on top of their usual treatments. The goal was …

This study tested whether a smartphone app called LowSalt4Life helps people with high blood pressure eat less salt and lower their blood pressure. About 410 adults with high blood pressure used the app, with some getting extra reminders and tips. The goal was to see if the app ma…

This study tested a culturally-tailored program that combines stress management, healthy eating, and exercise for African American women. 175 women with risk factors like high blood pressure or prediabetes took part. The goal was to see if the program could help them be more acti…

This study tested whether giving Black adults with high blood pressure free produce, personalized dietitian coaching, and resource referrals could help them eat a heart-healthy DASH diet. 80 participants were split into two groups to see if the program was practical and improved …

This study tested whether a structured exercise program, combined with usual care, could help normalize blood pressure patterns in 198 Chinese adults with hypertension who had a non-dipping blood pressure pattern (meaning their blood pressure doesn't drop enough during sleep). Pa…

This study tested two educational programs to help Hispanic adults with uncontrolled high blood pressure take their medication as prescribed. Over 500 participants were followed for 6 months to see which approach worked better. The goal was to improve medication adherence and ult…

This study tested a 4-month program where community health workers gave extra nutrition coaching to 60 patients with high blood pressure and food insecurity. The goal was to see if adding nutrition help to existing blood pressure support was practical and liked by patients. The s…

This study tested a blood pressure monitoring system to help older adults (65+) stick to their hypertension medication. 200 participants used the system for 6 months, with one group also getting extra strategies. The goal was to see if the system improved how consistently they to…

This study tested a new drug called lorundrostat in 1083 adults whose high blood pressure remained high despite taking 2 to 5 other blood pressure medicines. The goal was to see if adding lorundrostat could lower blood pressure more than a placebo. Participants took the drug or a…

This study tested a new drug called SLx-2101 in 38 adults with moderate to severe high blood pressure. Participants took either 5 mg or 10 mg of the drug once a day for 14 days. The goal was to see how well it lowered blood pressure and if it was safe.

This study tested if doing wall squats (a type of isometric exercise) can help lower blood pressure in Chinese adults with hypertension. 50 participants who were not very active were randomly assigned to do either wall squats or stretching exercises for 24 weeks. The main goal wa…

This study tested whether giving people a low-sodium salt substitute (where some sodium is replaced with potassium) through community health workers could lower blood pressure. About 618 adults in rural Bangladesh took part. The goal was to see if this simple dietary change could…

This study looked at whether combining high-intensity interval training (HIIT) with the DASH diet can help reduce artery stiffness in people with high blood pressure. Twenty adults with controlled hypertension participated. The goal was to see if this lifestyle approach improves …

This study tested a monthly injection called tonlamarsen in 206 adults whose blood pressure remained high despite taking at least two medications. The goal was to see if the drug could safely lower blood pressure by targeting a protein involved in blood pressure regulation. Parti…

This study looked at whether an educational worksheet plus health coaching could help people with chronic kidney disease and high blood pressure improve their blood pressure. About 320 adults with moderate to severe kidney disease took part. The goal was to see if this approach l…

This study looked at whether a combination drug (sacubitril/valsartan) can prevent atrial fibrillation from returning after a catheter ablation procedure in older adults with high blood pressure. About 320 people aged 55-80 took either the combination drug or a standard blood pre…

This study tested a program called Walk Together, designed to help African American adults with high blood pressure manage their condition with support from a family member. The program involved 62 participants and their chosen family partners. The main goal was to see if the pro…

This study tested whether a grape seed extract supplement (Enovita®) can help lower blood pressure in adults with elevated blood pressure or stage 1 hypertension. Over 8 weeks, 80 participants took either the supplement or a placebo. Researchers measured changes in blood pressure…

This study tested whether taking two medications together (DWC202206 and DWC202207) is safe and effective for people with both high blood pressure and high cholesterol. 214 adults aged 19 to 80 took part. The goal was to see if the combination lowered blood pressure and LDL (bad)…

This study tested whether adding a muscle relaxation technique to aerobic exercise helps people with early-stage high blood pressure more than exercise alone. Forty adults with stage 1 hypertension took part. Researchers measured blood pressure, heart rate, breathing rate, and qu…

This study tested whether providing medically tailored meals (MTMs) alone or combined with weekly group support sessions helps Black adults with high blood pressure, type 2 diabetes, or obesity. 75 participants received either meals only, meals plus group support, or delayed meal…

This early-phase study tested a new compound given under the tongue to see if it can lower blood pressure by boosting nitric oxide levels. Fourteen healthy adults took part. The goal was to measure changes in blood pressure and related chemicals in the blood. This approach might …

This study looked at two different ways to help people living with both HIV and high blood pressure in Uganda. The goal was to see which method works better to control blood pressure and save lives. Over 87,000 adults from HIV clinics took part, and researchers compared a simpler…

This study tested whether providing medically tailored meals, grocery vouchers, or a combination can improve health in low-resource families. 56 adults and children with food insecurity and conditions like type 2 diabetes or high blood pressure took part. Researchers measured cha…

This study tested whether a mobile app called Collabree helps adults over 50 with high blood pressure take their daily pills more regularly. 144 participants used the app or standard care for 90 days, with a 90-day follow-up. The goal was to improve medication adherence without c…

This study tested whether having people with uncontrolled high blood pressure check their own readings at home could help lower their numbers. 70 adults with hypertension were split into two groups: one group used a home monitor for 5 days each month, while the other group receiv…

This study tested a program where teenagers learn about high blood pressure and then teach an adult they know using a digital badge. Adults with high blood pressure and a teen partner were randomly assigned to either the blood pressure education badge or a job skills badge. The g…

This study tested a program to help African American women aged 40 and older who care for a family member with Alzheimer's or related dementia and also have high blood pressure. The program focused on stress management, healthy eating, and physical activity to improve blood press…

This study looked at whether bringing HIV and chronic disease care into the community and linking it with microfinance groups helps people with HIV stay in care and keep the virus under control. About 1,200 adults in rural Kenya took part. The goal was to see if this combined app…

This study tested whether a mobile app called Collabree helps people with high blood pressure take their daily pills more consistently. 181 adults in Switzerland who took at least 4 blood pressure pills a day participated. Participants were split into three groups, with two group…

This study tested whether taking two blood pressure medicines together (valsartan and hydrochlorothiazide) works better than taking just one (valsartan alone) in people with high blood pressure that has already affected their heart. A total of 118 adults aged 18 to 70 took part. …

This study compared two blood pressure treatments in 59 adults under 60 who were newly diagnosed with mild to moderate hypertension. One group took bisoprolol alone, while the other took a combination of valsartan and amlodipine. The goal was to see which medicine controlled bloo…

This study tested a new drug called lorundrostat in 285 adults whose high blood pressure remained uncontrolled despite taking 2 to 5 other medications. Participants added either lorundrostat or a placebo to their current regimen. The goal was to see if lorundrostat could safely l…

This study tested whether trained female community health volunteers could help prevent and control high blood pressure in rural Nepal. 520 adults with high blood pressure took part. The volunteers led group meetings to check blood pressure, provide health education, and support …

This study tested a lifestyle program designed for Native Hawaiian and Pacific Islander adults with conditions like prediabetes, type 2 diabetes, high blood pressure, or obesity. Community health workers delivered the program, which included support for social needs like housing …

This study tested a new way to manage high blood pressure in people living with HIV. Researchers worked with 30 health clinics in Nigeria to train staff in a task-sharing model, where nurses and community health workers help doctors provide care. The goal was to see if this appro…

This study tested whether eplerenone, a drug that blocks a hormone called aldosterone, can improve blood flow to the heart and reduce scarring better than a standard blood pressure drug (chlorthalidone) in people with obesity and high blood pressure. About 79 adults took part. Th…

This study tested a smartphone app called USeeBP to help African American adults with poorly controlled high blood pressure. 31 participants used the app alongside their usual care. The goal was to see if the app could help lower blood pressure readings.

This study looked at side effects and how well azilsartan controls blood pressure in children aged 6 to 15 with high blood pressure. Five children took the drug once daily for up to 12 months. Doctors monitored for any unwanted effects and measured blood pressure changes.

This study tested how often people with high blood pressure need to do isometric (static) exercises to lower their blood pressure. Thirty adults who were not on medication did these exercises once, twice, or three times per week. The goal was to find the smallest effective dose t…

This study tested whether an automatic blood pressure machine (WatchBP Office) is more accurate than the traditional manual method in Chinese adults with high blood pressure. 149 participants had their blood pressure measured three ways: automatic, traditional, and a 48-hour wear…

This study checked how well the Withings BPM Pro 2, an automatic blood pressure cuff, measures blood pressure compared to a standard method. About 89 adults with different arm sizes took part. The goal was to see if the device gives accurate readings for everyday use.

This study tested how accurately a Samsung Galaxy smartwatch can measure blood pressure over time. Researchers compared the watch's readings to those from a standard medical device. The study involved 42 healthy volunteers to see if the watch could be a reliable tool for monitori…

This study trained community health workers to screen Black men for early signs of high blood pressure. Participants received lifestyle advice and were linked to doctors and social services. The goal was to lower blood pressure and prevent future heart problems.

This study tested whether a single low-dose pill containing three blood pressure medicines could prevent another stroke in people who had a brain bleed (intracerebral hemorrhage). Over 1,600 adults with a history of such a bleed and slightly high blood pressure took either the tr…

This study looked at whether exercising in the morning or early evening makes a difference in blood pressure and blood vessel health for postmenopausal women with high blood pressure. Researchers measured nighttime blood pressure drops and how well blood vessels worked after exer…

This study looked at whether a sedative called dexmedetomidine, given through a vein, can prevent sudden rises in blood pressure and heart rate when a breathing tube is inserted. It involved 70 adults with controlled high blood pressure who were having planned surgery under gener…

This study compared two drugs, lignocaine and dexmedetomidine, given through a vein to prevent sudden rises in heart rate and blood pressure when a breathing tube is inserted for surgery. The trial involved 62 adults undergoing elective surgery. The goal was to see which drug bet…

This study tested a program that sends text reminders and uses social support and game-like features to encourage people with chronic kidney disease, diabetes, and high blood pressure to check their blood pressure regularly. 70 adults who own a smartphone took part. The goal was …

This study looked at 558 adults with mild to moderate sleep apnea who also get less than 7 hours of sleep most nights. Researchers compared two programs to see which one better reduces daytime sleepiness. The goal is to find the best way to help people feel more awake during the …

This study tested whether combining grocery delivery with health coaching helps adults with high blood pressure and limited food access eat a heart-healthy diet. 67 participants received an Instacart+ membership, weekly grocery lists, and coaching via text and video for 4 months.…

This study tested a personalized home exercise program for cancer survivors who also have diabetes or high blood pressure. Thirty-four participants chose from four exercise options (like walking or yoga) and used a wearable device to track their activity. The goal was to see if t…

This study looked at whether educational podcasts can help people with high blood pressure stick to their treatment and take better care of themselves. About 94 adults with high blood pressure took part. They listened to podcasts on Spotify designed to teach them about managing t…

This study compared two types of nerve blocks—erector spinae plane block and paravertebral block—for pain control after open kidney surgery. 72 adults aged 18-60 were split into two groups to see which block provided longer pain relief and better recovery. The goal is to improve …

This study tested whether a 5-minute calming virtual reality (VR) experience can lower blood pressure and anxiety in adults whose blood pressure rises in a clinic setting (white coat hypertension). 79 participants had their blood pressure and anxiety measured before and after the…

This study looked at whether eating dark chocolate can lower blood pressure and a heart-related chemical in the blood. 53 Thai men with high blood pressure ate either dark chocolate or white chocolate every day for two weeks, then switched. The goal was to see if theobromine, a n…

This study looked at whether taking peppermint oil by mouth can improve blood pressure and other heart health measures in people with mild to moderate high blood pressure. 40 adults aged 18-65 with systolic blood pressure between 120-139 mmHg who were not on blood pressure medica…

This study tested whether using nerve blocks with sedation instead of general anesthesia and opioids is safer and provides better pain control for high-risk patients needing an upper leg amputation. The study included 30 adults with conditions like diabetes, heart disease, or lun…

This study looked at whether giving magnesium sulfate and fentanyl before inserting a breathing tube can prevent sudden rises in blood pressure and heart rate in patients aged 50 and older. 76 people having planned surgery took part. The goal was to find a safer way to manage thi…

This study looked at 50 adults with heart failure (a condition where the heart doesn't pump blood well) and high blood pressure. Researchers compared two common blood pressure drugs—calcium channel blockers and beta-blockers—to see which one works better at lowering blood pressur…

This study looked at whether having new mothers check their blood pressure at home for 3 weeks after leaving the hospital can help find and manage high blood pressure early. Over 1,600 women took part. The goal was to see if home monitoring is practical and acceptable, and if it …

This study tested a web-based decision support tool to help primary care doctors in rural clinics better identify and manage high blood pressure in children aged 6-17. Over 41,000 children from 45 clinics in three Midwestern states took part. The goal was to see if the tool impro…

This study tested whether training early-career doctors and nurse practitioners to communicate more effectively with patients could help lower blood pressure. The training focused on reducing bias and building trust, especially with patients from minority and low-income backgroun…

This completed study looked at how genes, lifestyle, and social factors like stress and neighborhood affect heart disease risk in 670 African-American adults. Researchers collected blood samples, medical tests, and surveys to find links between ancestry-related DNA variants and h…

This study tested whether using a more accurate blood pressure reading (central aortic pressure) instead of the usual arm cuff helps manage blood pressure better in people with advanced chronic kidney disease. 116 adults with kidney failure risk were randomly assigned to either t…

This study looked at a program called COPE that helps Navajo people with diabetes and other chronic conditions. The program uses community health workers to support patients and connect them with doctors. Researchers compared people in the program to those not in it to see if it …

This study looked at how to better manage high blood pressure in people living with HIV in South Africa. Researchers worked with over 4,300 patients and healthcare workers to find barriers to care and design a practical program for clinics. The goal was to improve blood pressure …

This study looked at health records from over 155,000 older adults with high blood pressure to see if one type of blood pressure medication might lower the risk of developing dementia or Alzheimer's disease. Researchers compared two drugs, amiloride and triamterene, by analyzing …

This study looked back at 901 infants who had surgery for aortic coarctation (a narrowed heart artery) before age one. Researchers wanted to find out how many later developed high blood pressure or re-narrowing of the artery. The goal was to better understand these long-term risk…

This study looked at whether eating less salt before bed can improve blood pressure and body rhythms in people with obesity. Researchers measured blood pressure, body temperature, and sleep-related hormone changes in 53 adults. The goal was to learn how salt timing affects health…

This study aims to understand why people with high blood pressure respond differently to various medications. Researchers will look at factors like diet, body size, genetics, and hormone levels. 139 adults with mild to moderate high blood pressure will take several different drug…

This study tested a new single pill that combines two common heart medications (pitavastatin and valsartan) against taking them separately. 52 healthy men participated to see how the drugs are absorbed and processed by the body. The goal was to find out if the combination pill wo…

This study examined 200 patients who had surgery to clear blocked neck arteries. Researchers looked for bacteria inside the removed plaque and tracked whether certain bacteria were linked to later problems like stroke or re-narrowing of the artery. The goal was to learn which bac…

This small pilot study looked at whether aprepitant, a drug used for nausea, can lower a hormone called aldosterone in people with type 2 diabetes and high blood pressure. Five participants took either aprepitant or a placebo for two weeks, then switched. The goal was to understa…

This study looked at how different amounts of daily salt (sodium) change the way the diabetes drug ertugliflozin affects blood pressure and kidney function. Overweight adults with type 2 diabetes followed both a low-salt and a high-salt diet while taking the drug or a placebo. Th…

This study aims to find genetic differences that make some people more likely to develop high blood pressure. Researchers analyzed data from over 8,600 African American and Mexican American participants who had already taken part in other studies. The goal is to better understand…

This study looked at why people with a rare genetic condition called POR deficiency often develop high blood pressure and blood vessel damage. Researchers compared blood pressure readings and specific blood markers between 51 patients and healthy volunteers. The goal was to bette…

This study looked at medical records from over 163,000 older adults with high blood pressure to see if one type of blood pressure drug (dihydropyridine calcium channel blockers) was linked to a lower risk of developing dementia compared to another (hydrochlorothiazide). The goal …

This study looked at gut tissue from 35 people with and without high blood pressure who were already scheduled for a colonoscopy. Researchers grew mini-guts in the lab to compare gene activity and growth patterns. The goal was to understand if gut differences are linked to hypert…

This study looked at how two different exercise programs affect heart function and blood pressure in men over 45 with high blood pressure and heart disease. Forty participants did either interval or continuous training for 12 weeks. The goal was to see which type of exercise bett…

This study looked at health records from over 800,000 older adults to see if certain blood pressure medicines (propranolol or carvedilol) might lower the risk of developing dementia or Alzheimer's compared to other similar drugs. The goal was to find new uses for existing medicat…

This study looked at 149 adults with high blood pressure and insomnia to understand how poor sleep might increase heart disease risk. Researchers used a sleep therapy called CBT-I to see if improving sleep could lower nighttime blood pressure. The goal was to learn more about the…

This study looked at why men with prostate cancer who receive hormone therapy (ADT) often develop high blood pressure. Researchers measured how the nervous system and kidneys control blood pressure in 10 men before and after starting ADT. The goal was to understand the causes so …

This study looked at over 30,000 adults hospitalized in Maryland to understand why some patients wait in the emergency room after being admitted (called boarding) and how that affects costs and care. Researchers analyzed existing medical records to find patterns and financial imp…

This study looked at two methods for assigning care coordinators to older adults (65+) with heart disease or risk factors like diabetes and high blood pressure. The goal was to see which approach better prevented emergency room visits and hospitalizations. Researchers compared as…

This study looked at whether giving people of African ancestry with high blood pressure and their doctors the results of a genetic test for APOL1 gene variants could improve kidney disease management. Over 6,700 adults were randomly assigned to get the test results right away or …

This study looked at how different ways of doing resistance exercise (like lifting weights) affect the heart and blood vessels of women after menopause. Researchers compared women with normal blood pressure to those with high blood pressure. The goal was to understand how exercis…

This completed study looked at 130 adults with chronic kidney disease to see if a kidney protein called uromodulin changes how salt affects blood pressure. Researchers measured salt intake and 24-hour blood pressure to find links. The goal was to better understand why some patien…

This study tested whether teaching people who sleep less than 7 hours a night how to improve their sleep could lower their blood pressure while they sleep. 66 adults took part, with some getting sleep tips and others not. The main goal was to see if better sleep leads to healthie…

This study tested whether a planned awareness program could improve knowledge about preventing hypertensive crisis in people diagnosed with high blood pressure. 35 participants completed the program and their knowledge was measured before and after. The goal was to see if teachin…

This study followed 200 children and young adults who are overweight or have obesity and are at risk for high blood pressure. Researchers collected medical information over time to learn how excess weight affects the heart and blood vessels. The goal is to better understand these…

This study tested a new, non-invasive laser method (Laser Doppler Vibrometry) to measure artery stiffness in 100 adults with high blood pressure. The goal was to see if this new technique works as well as the current standard methods. The study did not provide any treatment, only…

This study looked at how high-intensity versus low-intensity strength training affects heart rate and blood pressure in people with high blood pressure. 28 participants completed the trial. The goal was to understand the immediate effects of different exercise intensities on hear…

This pilot study tested a quality improvement process to help staff at mental health clinics deliver better care for heart disease risk factors like diabetes, high blood pressure, and high cholesterol. Researchers worked with 85 participants, including clinic staff and people wit…

This study looked at 49 veterans with early chronic kidney disease to see if common water pills (diuretics) can reduce extra body fluid and improve heart health. Researchers measured changes in blood markers and symptoms like fatigue after 4 weeks of treatment. The goal was to la…

This study looked at how well a special wristband (Aktiia 24/7) tracks blood pressure in people with high blood pressure. About 1,729 adults wore the device for 12 weeks while researchers measured changes in their blood pressure and asked about their experience. The goal was to s…

This study looked at how stretchy the skin and blood vessels are in people with Williams syndrome, a genetic condition that can cause heart problems. Researchers measured skin and pulse speed in 43 participants aged 5 to 70 using gentle suction and a pencil-like probe. The goal w…

This study looked at the gut bacteria of 192 adults, including those with untreated high blood pressure, those on medication, and healthy people. Researchers compared stool samples to find which bacteria are different in people with hypertension. The goal is to uncover patterns t…

This study tested whether a personalized lifestyle program could help people with obesity and related conditions like prediabetes or high blood pressure improve their insulin resistance. Forty adults received either nutrition or exercise counseling first, and if they didn't impro…

This study tested whether an AI system (GPT) could help medical students learn how to manage high blood pressure better than standard teaching. 52 students were split into two groups: one used the AI, the other used traditional materials. Researchers compared test scores and stud…

This study looked at how African American adults with high blood pressure manage their condition and stay resilient. Researchers tracked 125 participants for 6 months, measuring blood pressure, quality of life, and self-care habits. The goal was to understand what helps people st…

This study looked at how a new drug called HL1113 works in the body. It was tested in 37 healthy adults to see how it is absorbed and if it is safe. The drug is designed to treat high blood pressure and type 2 diabetes. The study was completed and helps researchers understand how…

This early-phase study looked at whether drinking beetroot juice (rich in natural nitrates) could improve artery stiffness and brain blood flow in adults aged 50-79. Sixteen participants were randomly given either nitrate-rich or nitrate-free beetroot juice. The goal was to see i…

This small study looked at whether a short exercise program could improve thinking skills and blood vessel health in older adults (ages 55-75) with high blood pressure. Eleven participants exercised on a stationary bike and had their fitness, eye blood vessels, and memory tested …

This study examined how Ramadan fasting changes blood pressure in 150 healthy adults and those with stable high blood pressure. Participants had their blood pressure monitored around the clock during the fasting period. The goal was to understand if fasting affects blood pressure…

This study tested a computer tool that helps doctors find and address social needs—like food, housing, or transportation—in African American patients with low income and chronic diseases such as diabetes or high blood pressure. The tool gave doctors a risk score and suggested ref…

This study looked at 72 adults with high blood pressure to see if the concentration of their urine is related to the stiffness of their arteries. The goal was to better understand how the kidneys, heart, and blood vessels interact. Participants provided urine samples and had thei…

This study looked at whether taking a synbiotic (a mix of probiotics and prebiotics) for 30 days could improve gut health, weight, and heart health in 47 healthy adults aged 18-60. Participants were randomly assigned to receive either the supplement or a placebo. The goal was to …

This study explored whether certain gene changes in the apelin system are linked to coronary artery disease and high blood pressure. Researchers analyzed blood samples from 223 Syrian patients to measure apelin levels and look for specific genetic variations. The goal was to bett…

This study looked at whether a supplement called MitoQ can improve blood vessel function and lower blood pressure in Black and non-Black adults aged 45-75. Researchers wanted to understand if problems with tiny energy-producing parts of cells (mitochondria) help explain why Black…

This small study looked at whether drinking a KETO5 XOGenius beverage daily could improve markers of heart and brain health in 6 healthy adults aged 18-50. Researchers measured blood pressure, cholesterol, artery stiffness, and cognitive function. The goal was to gather initial d…

This pilot study tested whether giving people small cash rewards each week (instead of a lump sum at the end) would encourage them to check their blood pressure at home more regularly. Fifty adults with uncontrolled high blood pressure from community health centers took part for …

This study looked at existing data from over 1,600 African Americans aged 30-55 with severe high blood pressure. Researchers examined genetic, behavioral, and social factors to better understand why this group is more affected. No new participants were enrolled; the goal was to l…

This study looked at how well different blood pressure medicines work in people of White, Black, and South Asian backgrounds. About 940 adults aged 18 to 65 took part. The goal was to see if treatment responses vary by ethnicity, which could help doctors choose the right drug for…