HYPERTENSION
Clinical trials for HYPERTENSION explained in plain language.
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Neighbors helping neighbors: local health workers tackle chronic diseases in rural mexico
Disease control CompletedThis study tested whether adding trained community health workers to regular clinic care helps people in rural Mexico better manage their diabetes and high blood pressure. Researchers followed 168 adults over time to see if this approach improved how consistently people took thei…
Matched conditions: HYPERTENSION
Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Apr 01, 2026 21:26 UTC
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Special program aims to close racial gap in blood pressure control
Disease control CompletedThis study tested a 12-week program to help African American and Latinx patients better manage their high blood pressure. A team including a community health worker, nurse, pharmacist, and social worker provided support and education. Patients used a cellular-connected blood pres…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Rush University Medical Center • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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Monthly shot tested for stubborn high blood pressure
Disease control CompletedThis study tested whether a monthly injection called tonlamarsen could help lower blood pressure in adults whose high blood pressure wasn't controlled despite taking two or more medications. Researchers compared the injection to a placebo in 206 participants over 20 weeks to see …
Matched conditions: HYPERTENSION
Phase: PHASE2 • Sponsor: Kardigan, Inc. • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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Grocery delivery and coaching tested to fight high blood pressure
Disease control CompletedThis study tested whether a digital program could help adults with high blood pressure eat healthier. 67 participants with limited access to quality food received a grocery delivery membership, personalized shopping lists, and health coaching for 4 months. Researchers wanted to s…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New pill aims to tame sleep apnea and high blood pressure together
Disease control CompletedThis study tested whether a daily oral medication called lorundrostat could help adults who have both moderate-to-severe obstructive sleep apnea and high blood pressure. In this 48-person trial, participants took either the study drug or a placebo for four weeks, then switched af…
Matched conditions: HYPERTENSION
Phase: PHASE2 • Sponsor: Mineralys Therapeutics Inc. • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Phones and nurses team up to tackle stubborn diabetes and hypertension
Disease control CompletedThis study tested whether using mobile monitoring devices and getting support from nurses could help people better manage their type 2 diabetes and high blood pressure. It involved 220 adults whose conditions were not well controlled with standard clinic care. Researchers compare…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Duke University • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Cash for checks: does paying people weekly help control high blood pressure?
Disease control CompletedThis small pilot study tested if giving people weekly cash payments helps them check their blood pressure at home more consistently than getting one payment at the end of the study. Researchers enrolled 50 adults with uncontrolled high blood pressure from Louisiana community heal…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Tulane University • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Massive trial tests new ways to protect HIV patients from heart disease
Disease control CompletedThis study tested two different strategies to help people living with HIV in Uganda better manage their high blood pressure. It involved over 87,000 adults at 16 clinics and compared a basic approach (providing free equipment and medication) with a more intensive strategy that in…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Infectious Diseases Research Collaboration, Uganda • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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RNA drug trial aims to tame silent killer
Disease control CompletedThis study tested an experimental drug called ALN-AGT01, designed to lower blood pressure in adults with mild-to-moderate hypertension. Nearly 400 participants received either the drug or a placebo for up to a year to see how well it worked and how safe it was. The goal was to se…
Matched conditions: HYPERTENSION
Phase: PHASE2 • Sponsor: Alnylam Pharmaceuticals • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Nurse-Led program aims to help stroke patients manage recovery at home
Disease control CompletedThis study tested whether a special education program led by nurses could help stroke patients manage their recovery better than standard follow-up care. The program involved teaching patients and a family member or caregiver about managing high blood pressure and stroke recovery…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: University Hospital, Lille • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Can text messages and game points tame high blood pressure?
Disease control CompletedThis pilot study tested a program called SMART-HABITS-4-Health to see if it could help people with chronic kidney disease, diabetes, and high blood pressure manage their condition better. 70 participants used a smartphone app to track their blood pressure and received daily text …
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: University of Pennsylvania • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Can a coach and a worksheet slow kidney disease?
Disease control CompletedThis study tested whether a personalized educational worksheet and follow-up phone coaching could help people with chronic kidney disease (CKD) better manage their high blood pressure. 320 participants with moderate to severe CKD and uncontrolled blood pressure were assigned to r…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: University of Michigan • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Community health workers tested as key to blood pressure control
Disease control CompletedThis study tested three different approaches to help adults with high blood pressure in rural South Africa. Researchers compared standard clinic care against two programs using community health workers, with one adding home blood pressure monitoring. The goal was to find which me…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Apr 01, 2026 14:40 UTC
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New pill targets stubborn high blood pressure when standard meds fail
Disease control CompletedThis study tested whether a new drug called lorundrostat could help lower blood pressure in people whose high blood pressure wasn't controlled by their current medications. 285 adults with uncontrolled hypertension took either the new drug or a placebo pill in addition to a stand…
Matched conditions: HYPERTENSION
Phase: PHASE2 • Sponsor: Mineralys Therapeutics Inc. • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Can a daily beetroot shot keep your brain young?
Disease control CompletedThis small, early-stage study tested whether drinking beetroot juice could improve blood flow to the brain and reduce artery stiffness in adults aged 50-79. Sixteen participants were randomly assigned to drink either regular beetroot juice or a version with the key ingredient rem…
Matched conditions: HYPERTENSION
Phase: EARLY_PHASE1 • Sponsor: Gary L. Pierce, PhD • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Can a few classes help people stick to their blood pressure pills?
Disease control CompletedThis study tested whether personalized educational sessions could help adults with uncontrolled high blood pressure take their medication more consistently. It involved 511 Hispanic adults who were randomly assigned to one of two educational programs. Researchers tracked if parti…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: University of California, Irvine • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Can a few minutes a week tame high blood pressure?
Disease control CompletedThis study tested whether doing a special type of strength training just once or twice a week could lower high blood pressure as effectively as doing it three times a week. It involved 30 adults with high or borderline-high blood pressure who were not on medication. The goal was …
Matched conditions: HYPERTENSION
Phase: PHASE3 • Sponsor: The University of Northampton • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Local helpers tackle high blood pressure and hunger
Disease control CompletedThis study tested whether trained community health workers could help adults with high blood pressure who struggle to afford healthy food. 75 participants from specific Florida zip codes were randomly assigned to receive either basic information, educational sessions, or educatio…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: University of Florida • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Home monitoring tested to tame high blood pressure
Disease control CompletedThis study tested whether having patients monitor their own blood pressure at home helps lower high blood pressure levels. Seventy adults with uncontrolled hypertension were split into two groups: one used a loaned home monitor, while the other only had their pressure checked at …
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Universidade Federal do Ceara • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Your phone could help lower your blood pressure
Disease control CompletedThis study tested whether a smartphone app could help people with high blood pressure reduce their salt intake and improve their blood pressure. Researchers enrolled 410 adults with stable high blood pressure to use the app, which sent personalized reminders about healthy eating.…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: University of Michigan • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Exercise prescription tested to tame high blood pressure
Disease control CompletedThis study tested whether a structured, 12-week exercise program could help normalize blood pressure patterns in Chinese adults with high blood pressure who were not exercising enough. Researchers compared the exercise program plus usual medical care to usual care alone in 198 pa…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Chinese University of Hong Kong • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Could a buckwheat diet tame your blood pressure?
Disease control CompletedThis study tested whether a special diet based on tartary buckwheat could help lower high blood pressure in adults. Researchers compared the diet to standard lifestyle advice in 130 participants to see if it worked and was safe. They also wanted to understand if the diet helped b…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Chinese Academy of Medical Sciences, Fuwai Hospital • Aim: Disease control
Last updated Mar 31, 2026 12:10 UTC
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Can your workout boost your brain? new study tests exercise intensity
Disease control CompletedThis study tested whether 10 weeks of exercise could improve brain health and lower blood pressure in adults with high blood pressure and a higher body weight. Researchers compared the effects of moderate versus high-intensity workouts. The goal was to see if exercise could help …
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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New clinic system aims to tame silent killer in HIV patients
Disease control CompletedThis project tested a new system to help clinics in Mozambique better screen for and manage high blood pressure in people living with HIV. The goal was to use existing HIV care services to catch and control high blood pressure more effectively, as the two conditions often occur t…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Eduardo Mondlane University • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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Local health guides tested to fight chronic illness in underserved communities
Disease control CompletedThis study tested whether pairing people with a community health worker for 10 months could help them better manage chronic health conditions like diabetes, high blood pressure, and obesity. The program provided navigation help to access health services, education, and support fo…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Baylor Research Institute • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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Could a common pill protect the hearts of millions with obesity?
Disease control CompletedThis study tested if a medication called eplerenone could improve heart health in overweight or obese people with high blood pressure or related conditions. It compared eplerenone to another standard blood pressure drug to see which was better at improving blood flow and reducing…
Matched conditions: HYPERTENSION
Phase: PHASE4 • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Head-to-Head: which blood pressure pill works better for younger adults?
Disease control CompletedThis study compared two common approaches for treating high blood pressure in adults under 60. Researchers tested a single beta-blocker pill against a combination pill containing two different medications. The goal was to see which approach better controlled blood pressure over t…
Matched conditions: HYPERTENSION
Phase: PHASE4 • Sponsor: Shiraz University of Medical Sciences • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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New drug shows promise for stubborn high blood pressure
Disease control CompletedThis large, completed Phase 3 trial tested whether a new drug called lorundrostat could lower blood pressure in people whose high blood pressure wasn't controlled despite taking 2 to 5 other medications. Over 1,000 participants were randomly assigned to receive either the new dru…
Matched conditions: HYPERTENSION
Phase: PHASE3 • Sponsor: Mineralys Therapeutics Inc. • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Doctors prescribe podcasts to fight high blood pressure
Disease control CompletedThis study tested whether listening to educational podcasts could help people with high blood pressure better manage their condition. Researchers enrolled 94 patients and split them into two groups: one listened to podcasts about hypertension, while the other did not. The goal wa…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Firat University • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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Tailored program aims to break Stress-Health link for black women
Disease control CompletedThis study tested a culturally tailored program designed to help African American women manage stress, improve their diet, and increase physical activity. The goal was to see if this approach could lower their risk for heart disease, stroke, and diabetes. 175 women who were overw…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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Families unite to fight high blood pressure in new health program
Disease control CompletedThis study tested a new program called 'Walk Together' that involves family members to help African American adults better manage their high blood pressure. The program focused on lifestyle changes like diet and exercise, with family support as a key component. Researchers wanted…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: University of Texas Southwestern Medical Center • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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Phone app aims to help kidney patients stay on track
Disease control CompletedThis small pilot study tested whether a smartphone app could help people with chronic kidney disease and high blood pressure better manage their health. The app sent reminders to check blood pressure and walk more, and provided feedback and educational resources. Researchers want…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: University of Pennsylvania • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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Old antibiotic tested as new weapon against stubborn hypertension
Disease control CompletedThis study tested whether minocycline, a common antibiotic, could help lower blood pressure in people whose high blood pressure was not controlled by three or more standard medications. Researchers gave 34 participants increasing doses of minocycline over six months to see if it …
Matched conditions: HYPERTENSION
Phase: PHASE2 • Sponsor: University of Florida • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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Can free healthy meals and group support fight heart disease in High-Risk communities?
Disease control CompletedThis study tested whether providing free, healthy meals designed for medical conditions, with or without weekly group health sessions, could help people manage high blood pressure, diabetes, and obesity. It involved 75 Black adults from a Cleveland community with high rates of he…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Amanda Shallcross • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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VA tests virtual nurse program to slash heart attack risk for veterans with HIV
Disease control CompletedThis study tested whether a special nurse-led program could help Veterans with HIV lower their blood pressure and reduce their risk of heart disease. The program involved 305 Veterans and combined care coordination, medication support, home blood pressure monitoring, and video ch…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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Mindfulness & diet program aims to ease double burden for black caregivers
Disease control CompletedThis small, completed pilot study tested a telehealth program designed to help Black women who are caregivers for family members with dementia. The program combined mindfulness exercises and a heart-healthy diet plan (DASH) to see if it could help them manage their chronic stress…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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Could peppermint oil lower your blood pressure?
Disease control CompletedThis study tested whether taking peppermint oil supplements could help improve heart health in people with mild to moderate high blood pressure. Forty participants who were not on blood pressure medication took either peppermint oil or a placebo. Researchers measured blood pressu…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: University of Central Lancashire • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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Community health workers deliver special salt in fight against high blood pressure
Disease control CompletedThis study tested if providing a special low-sodium salt substitute could help lower blood pressure in adults in rural Bangladesh. Researchers gave the salt to 309 households through community health workers to see if this was a practical way to help people. They measured blood p…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Stanford University • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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New approach aims to keep seniors with heart risks out of the hospital
Disease control CompletedThis study tested a new way to decide which older adults should get extra help from a care coordinator. Researchers wanted to see if asking people about their own difficulties managing care was better at preventing emergency room visits and hospital stays than the usual method, w…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Weill Medical College of Cornell University • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Can relaxing your muscles help lower your blood pressure?
Disease control CompletedThis study tested whether combining a specific muscle relaxation technique with regular aerobic exercise is better than exercise alone for people with early-stage high blood pressure. Researchers compared two groups of 40 adults to see if the combination improved blood pressure, …
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Foundation University Islamabad • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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Can simple wall squats lower your blood pressure?
Disease control CompletedThis small pilot study tested whether a simple wall squat exercise program could help lower blood pressure in Chinese adults with hypertension who don't exercise regularly. Fifty participants were randomly assigned to either do wall squats or stretching exercises for 24 weeks. Re…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Chinese University of Hong Kong • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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Can a simple pill protect kidneys and hearts?
Disease control CompletedThis study tested if common, inexpensive water pills (diuretics) could help people with early-stage chronic kidney disease. Researchers wanted to see if reducing extra body fluid with these pills could lower the risk of heart problems and improve symptoms like tiredness. They mea…
Matched conditions: HYPERTENSION
Phase: PHASE4 • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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Phone app aims to tame silent killer in At-Risk community
Disease control CompletedThis study tested whether adding a special smartphone app could help African American adults with poorly controlled high blood pressure. The app connected to a home blood pressure cuff, sent readings to doctors, and provided medication reminders and health tips. Researchers wante…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: University of Chicago • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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New hope to slow deadly lung disease progression
Disease control CompletedThis study tested whether adding a new drug called ralinepag to standard treatments could help people with pulmonary arterial hypertension (PAH), a serious lung and heart condition. It involved 687 adults with PAH who were already on stable medication. The main goal was to see if…
Matched conditions: HYPERTENSION
Phase: PHASE3 • Sponsor: United Therapeutics • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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Can groceries be medicine? study tests food prescriptions for families in need
Disease control CompletedThis study tested whether providing healthy food resources to entire families could improve their health. It enrolled 56 low-income families in Kentucky where an adult had high blood pressure or type 2 diabetes and a child had a high weight. Families received medically tailored m…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Alison Gustafson • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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Scientists test which workout best tames dangerous blood pressure swings
Disease control CompletedThis study tested two different 12-week exercise programs for men over 45 with high blood pressure and coronary artery disease. Researchers wanted to see which type of workout—interval training or continuous training—was better at smoothing out dangerous short-term blood pressure…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: IRCCS San Raffaele Roma • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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Community-Led program aims to turn the tide on chronic disease for pacific islanders
Disease control CompletedThis study tested a lifestyle program designed specifically for Native Hawaiian and Pacific Islander communities to help control chronic health conditions like diabetes, high blood pressure, and high cholesterol. The program combined nutrition and exercise coaching with support f…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: University of Hawaii • Aim: Disease control
Last updated Mar 30, 2026 14:27 UTC
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New hope for controlling tough high blood pressure in kidney patients
Disease control CompletedThis study tested whether a new drug called KBP-5074 could safely lower high blood pressure in people who also have moderate-to-severe chronic kidney disease. About 162 participants were randomly assigned to receive either one of two doses of the drug or a placebo pill for 84 day…
Matched conditions: HYPERTENSION
Phase: PHASE2 • Sponsor: KBP Biosciences • Aim: Disease control
Last updated Mar 30, 2026 14:27 UTC
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New clinic strategy aims to tame silent killer in HIV patients
Disease control CompletedThis study tested a new way to manage high blood pressure in people living with HIV. It involved 960 patients across 30 primary health centers in Nigeria. The goal was to see if training and supporting clinic staff could successfully combine blood pressure care with existing HIV …
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Dr. Dike Ojji • Aim: Disease control
Last updated Mar 27, 2026 12:41 UTC
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New hope to stop irregular heartbeat comeback after surgery
Disease control CompletedThis study tested if a medication called sacubitril/valsartan is better than a standard drug at preventing a return of irregular heartbeats after a corrective heart procedure. It involved 320 older adults with high blood pressure and atrial fibrillation who had undergone a cathet…
Matched conditions: HYPERTENSION
Phase: PHASE4 • Sponsor: Shanghai Jiao Tong University School of Medicine • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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Teens become teachers in fight against high blood pressure
Disease control CompletedThis study tested whether a 6-week digital education program, where teens learn about high blood pressure and then teach an adult they know, could help lower the adult's blood pressure. Researchers worked with teens and adults to design the program, then enrolled pairs (one adult…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Rutgers, The State University of New Jersey • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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New study tests two paths to better health: lose weight or just get active?
Disease control CompletedThis small pilot study tested two different health coaching strategies for Black adults with obesity and related conditions like high blood pressure or prediabetes. One approach focused on weight loss, while the other focused on increasing physical activity without emphasizing we…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Community program tested to fight diabetes in navajo nation
Disease control CompletedThis study looked at a community health program called COPE that has been running in the Navajo Nation since 2009. It aimed to see if the program helped people with diabetes better manage their condition by improving blood sugar, blood pressure, and other health measures. Researc…
Matched conditions: HYPERTENSION
Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Study challenges routine blood pressure pills for the frail elderly
Disease control CompletedThis study tested whether carefully reducing or stopping blood pressure medication is safe and beneficial for frail older adults living in nursing homes who already have low blood pressure. Over 500 residents were randomly assigned to either have their medications reduced or to c…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: University of Alberta • Aim: Disease control
Last updated Mar 27, 2026 12:37 UTC
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Evening workouts may beat morning for blood pressure
Disease control CompletedThis study investigated whether exercising in the morning or early evening is more effective for lowering high blood pressure. Researchers worked with 68 older women who had hypertension to compare the effects of exercise timing. The goal was to see if evening exercise, similar t…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Michigan State University • Aim: Disease control
Last updated Mar 25, 2026 14:09 UTC
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Scientists test Quick-Dissolve blood pressure pill
Disease control CompletedThis small, early-stage study tested a new compound placed under the tongue to see if it could safely lower blood pressure in healthy volunteers. Researchers wanted to see if this method could deliver a blood vessel-relaxing molecule into the bloodstream more effectively than som…
Matched conditions: HYPERTENSION
Phase: EARLY_PHASE1 • Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated Mar 25, 2026 14:09 UTC
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Pill vs. machine: a new hope for sleep apnea blood pressure?
Disease control CompletedThis study tested if a pill called bosentan could lower blood pressure as well as the standard CPAP breathing machine in people with sleep apnea and mild high blood pressure. It involved 19 participants who were not taking blood pressure medication. The goal was to see if blockin…
Matched conditions: HYPERTENSION
Phase: PHASE2 • Sponsor: University Hospital, Grenoble • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Doctors test 'Smart' program that adjusts treatment for weight and blood sugar issues
Disease control CompletedThis study tested a flexible lifestyle program for people with conditions like insulin resistance, obesity, or prediabetes. It started with either nutrition or exercise counseling. If a person's insulin resistance didn't improve enough after 8 weeks, the program could switch them…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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New drug tested to tame Tough-to-Treat high blood pressure
Disease control CompletedThis study tested an investigational drug called zilebesiran in adults with high cardiovascular risk and high blood pressure that was not well-controlled despite taking standard medications. The goal was to see if adding zilebesiran could safely lower blood pressure more effectiv…
Matched conditions: HYPERTENSION
Phase: PHASE2 • Sponsor: Alnylam Pharmaceuticals • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Blood pressure drug showdown for common heart failure type
Disease control CompletedThis study compared two common blood pressure medications—amlodipine (a calcium channel blocker) and metoprolol (a beta-blocker)—in 50 adults with both high blood pressure and a specific type of heart failure where the heart pumps normally but doesn't relax well. The goal was to …
Matched conditions: HYPERTENSION
Phase: PHASE4 • Sponsor: University of Pennsylvania • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Home blood pressure checks could save new moms from Life-Threatening danger
Disease control CompletedThis study tested if checking blood pressure at home for three weeks after giving birth is a useful way to catch dangerous high blood pressure early. Over 1,600 new mothers participated to see if this remote monitoring helps them follow medical guidelines, reduces emergency visit…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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Doctors get special training to better connect with patients, lower blood pressure
Disease control CompletedThis study tested a training program for doctors-in-training and nurse practitioner students to improve how they communicate with and care for minority and low-income patients with high blood pressure. The goal was to see if this training would help patients achieve lower blood p…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Disease control
Last updated Mar 23, 2026 15:19 UTC
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Money and medicine: kenyan trial tests if microfinance boosts HIV treatment success
Disease control CompletedThis study tested a new way to help people with HIV in rural Kenya stay in care and keep their virus under control. Researchers combined local HIV and chronic disease check-ups with existing community savings groups. They wanted to see if making care easier to access and improvin…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Brown University • Aim: Disease control
Last updated Mar 23, 2026 15:19 UTC
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Doctors use new computer alert to tackle hidden causes of poor health
Disease control CompletedThis study tested a new computer tool for doctors. The tool automatically flags patients with chronic diseases who may also be struggling with needs like stable housing, food, or transportation. Doctors could then refer these patients to community organizations for help, aiming t…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Mar 23, 2026 15:18 UTC
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New clinic program aims to tame high blood pressure in people with HIV
Disease control CompletedThis study tested a new clinic program designed to improve high blood pressure care for adults living with HIV in South Africa. The program trained healthcare workers and used new systems to better screen for and manage high blood pressure during regular HIV clinic visits. Resear…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: University of Witwatersrand, South Africa • Aim: Disease control
Last updated Mar 23, 2026 15:17 UTC
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New shot aims to tame stubborn high blood pressure
Disease control CompletedThis study tested an experimental drug called zilebesiran in adults whose high blood pressure was not well controlled by their current medication. Over 660 participants received either the new drug or a placebo as an add-on to their standard treatment. The main goal was to see if…
Matched conditions: HYPERTENSION
Phase: PHASE2 • Sponsor: Alnylam Pharmaceuticals • Aim: Disease control
Last updated Mar 23, 2026 15:17 UTC
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Can a simple text save a life? study tests phone alerts for homeless health
Disease control CompletedThis study tested whether sending helpful text messages could improve blood pressure control for homeless adults in New York City shelters. About 120 participants with uncontrolled high blood pressure were randomly assigned to receive either general health texts or specific texts…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: George Washington University • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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Can cutting carbs beat high blood pressure in At-Risk communities?
Disease control CompletedThis study tested if adding a very low-carbohydrate diet to standard care could help lower blood pressure in lower-income African American adults. It involved 64 participants with high blood pressure or risk factors for heart disease. The main goal was to see if this specific die…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Baylor Research Institute • Aim: Disease control
Last updated Mar 23, 2026 15:14 UTC
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Phone app aims to tackle forgotten pills for high blood pressure
Disease control CompletedThis study tested whether a smartphone app called Collabree could help adults with high blood pressure remember to take their daily medication. Researchers in Switzerland randomly assigned 181 participants to either use the app or receive standard care to see if the app improved …
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Collabree AG • Aim: Disease control
Last updated Mar 23, 2026 15:14 UTC
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Blood pressure breakthrough: tailored treatments for every background
Disease control CompletedThis study aimed to find out if common blood pressure medications work differently for people of different ethnic backgrounds. Researchers tested several standard drugs on 940 White, Black, and South Asian adults in the UK to see which treatments controlled blood pressure best fo…
Matched conditions: HYPERTENSION
Phase: PHASE4 • Sponsor: Cambridge University Hospitals NHS Foundation Trust • Aim: Disease control
Last updated Mar 19, 2026 14:56 UTC
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New combo pill beats single drug for blood pressure control
Disease control CompletedThis study tested whether adding a second blood pressure medication (amlodipine) to an existing drug (LCZ696) works better than using LCZ696 alone. It involved 718 adults with mild-to-moderate high blood pressure that wasn't fully controlled on just LCZ696. The goal was to see if…
Matched conditions: HYPERTENSION
Phase: PHASE3 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Mar 19, 2026 14:56 UTC
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Sleep study tests education vs. breathing device for daytime fatigue
Disease control CompletedThis study tested two different programs to help adults with mild to moderate sleep apnea who also don't get enough sleep. Researchers compared a sleep education program alone against the same education plus a breathing machine (PAP device). The goal was to see which approach bet…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Wayne State University • Aim: Disease control
Last updated Mar 19, 2026 14:56 UTC
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Could your daily chocolate fix help your heart?
Disease control CompletedThis study tested whether eating dark chocolate daily could help lower blood pressure and reduce a specific heart disease risk marker in men with high blood pressure. 53 Thai men with hypertension ate either dark chocolate or white chocolate daily for two weeks, then switched aft…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Chiang Mai University • Aim: Disease control
Last updated Mar 19, 2026 14:56 UTC
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Local health workers tackle silent killer in HIV patients
Disease control CompletedThis study tested a new community health worker program designed to help people living with HIV better manage their high blood pressure in Tanzania. The program involved training local health workers to provide counseling, monitor blood pressure, and help patients get medication …
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Duke University • Aim: Disease control
Last updated Mar 19, 2026 14:55 UTC
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New blood pressure check aims to protect failing kidneys
Disease control CompletedThis pilot study tested whether using a new type of blood pressure measurement, taken from the body's central arteries, is a better way to manage high blood pressure in people with advanced kidney disease. The goal was to see if this method is practical for doctors and patients t…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal • Aim: Disease control
Last updated Mar 18, 2026 18:25 UTC
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Serve, volley, lower pressure: beach tennis tested as hypertension therapy
Disease control CompletedThis study tested whether playing recreational beach tennis twice a week for 12 weeks could help lower blood pressure in adults with hypertension. Researchers compared 42 participants who played beach tennis to a group that did not exercise, measuring their 24-hour blood pressure…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Hospital de Clinicas de Porto Alegre • Aim: Disease control
Last updated Mar 18, 2026 18:25 UTC
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Could a grape seed pill help tame your blood pressure?
Disease control CompletedThis study tested whether taking a daily grape seed extract supplement could help lower blood pressure in adults with mildly elevated levels. For 8 weeks, 80 participants either took the supplement or a placebo pill, without knowing which one they received. Researchers measured c…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Liaquat University of Medical & Health Sciences • Aim: Disease control
Last updated Mar 18, 2026 14:41 UTC
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New study tests stricter blood pressure rules for new moms
Disease control CompletedThis small pilot study tested whether it's practical and helpful to use stricter blood pressure targets for new mothers who had high blood pressure during pregnancy. It compared keeping blood pressure under 135/85 (tight control) to the usual target of under 150/100. The goal was…
Matched conditions: HYPERTENSION
Phase: PHASE4 • Sponsor: Alisse Hauspurg • Aim: Disease control
Last updated Mar 17, 2026 13:09 UTC
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Community takes steps to fight high blood pressure
Disease control CompletedThis study tested a 6-month community program designed to help Native Hawaiian and Pacific Islander adults better manage their high blood pressure. The program provided weekly education on healthy eating, traditional foods, medication use, and exercise, supported by text messages…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Washington State University • Aim: Disease control
Last updated Mar 16, 2026 15:25 UTC
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First look at blood pressure drug for kids
Disease control CompletedThis study monitored children aged 6 to 16 with high blood pressure who were taking the medication azilsartan. The main goals were to check for any side effects and see how well the drug controlled their blood pressure over 12 months. Doctors followed standard care practices whil…
Matched conditions: HYPERTENSION
Sponsor: Takeda • Aim: Disease control
Last updated Mar 16, 2026 15:25 UTC
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Fresh food & coaching tested to fight high blood pressure in black communities
Disease control CompletedThis pilot study tested a personalized program to help Black adults with high blood pressure eat healthier. 80 participants from areas with limited access to fresh food were randomly assigned to receive either standard produce bags or an enhanced program with produce prescription…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Mar 11, 2026 14:53 UTC
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New clinic program aims to untangle care for patients with multiple illnesses
Disease control CompletedThis study tested a new support program for clinics to improve care for adults with multiple long-term conditions like HIV, diabetes, and high blood pressure. Over 1,800 participants in South Africa either received standard care or the new ENHANCE program, which included special …
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: University of KwaZulu • Aim: Disease control
Last updated Mar 11, 2026 14:52 UTC
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Special nurses help patients tame high blood pressure
Disease control CompletedThis study looked at whether adding support from specially trained Advanced Practice Nurses (APNs) to regular doctor visits helps people with high blood pressure control it better. Researchers compared 483 patients who received this extra nurse support to those who got usual care…
Matched conditions: HYPERTENSION
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Mar 10, 2026 12:54 UTC
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Zapping kidney nerves to tame stubborn high blood pressure
Disease control CompletedThis study tested if a medical procedure could safely lower blood pressure in people whose high blood pressure wasn't controlled by up to three standard medications. Doctors used a special device to disrupt tiny nerves near the kidneys, which are thought to play a role in regulat…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Medtronic Vascular • Aim: Disease control
Last updated Mar 09, 2026 14:25 UTC
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New drug duo tested to tame stubborn high blood pressure
Disease control CompletedThis study tested whether adding a second drug (DWC202314) to an existing one (DWC202404) could better control high blood pressure in patients where the first drug alone wasn't enough. It involved 192 adults with essential hypertension whose blood pressure remained too high on si…
Matched conditions: HYPERTENSION
Phase: PHASE3 • Sponsor: Daewoong Pharmaceutical Co. LTD. • Aim: Disease control
Last updated Mar 09, 2026 14:25 UTC
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Home tech trial aims to catch dangerous blood pressure spikes in cancer care
Disease control CompletedThis study tested whether using a remote monitoring system to track blood pressure at home works better than a paper logbook for cancer patients taking a specific drug (bevacizumab) that can raise blood pressure. It involved 20 patients to see if the remote system helped patients…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: West Michigan Cancer Center • Aim: Disease control
Last updated Mar 04, 2026 15:29 UTC
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Local women take on silent killer in their communities
Disease control CompletedThis study tested whether trained female community health volunteers could help people manage high blood pressure in Nepal. Over 500 adults with high blood pressure were assigned to either receive support from these volunteers or continue with usual care. The volunteers led group…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Kathmandu University School of Medical Sciences • Aim: Disease control
Last updated Mar 02, 2026 15:28 UTC
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Tablet app aims to fight anemia and high blood pressure in pregnant women
Disease control CompletedThis study tested whether a digital health program on tablets could help community health workers better screen and manage health risks for pregnant women in rural India. Over 3,400 women participated to see if the program could reduce anemia and improve follow-up care for high b…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: The George Institute • Aim: Disease control
Last updated Mar 02, 2026 15:23 UTC
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Live coach vs video: which exercise works best for blood pressure?
Disease control CompletedThis study tested two ways to deliver exercise therapy at home for people with high blood pressure. One group exercised with live video guidance from a therapist, while another followed pre-recorded exercise videos. Researchers measured how these different approaches affected blo…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Hacettepe University • Aim: Disease control
Last updated Mar 02, 2026 15:22 UTC
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Digital helper aims to catch silent threat in young patients
Diagnosis CompletedThis study tested a computer tool designed to help primary care doctors in rural areas better recognize high blood pressure in children and teenagers. The tool gives doctors real-time guidance during checkups, reminding them when a child's blood pressure reading is high and sugge…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: HealthPartners Institute • Aim: Diagnosis
Last updated Apr 01, 2026 14:42 UTC
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Can your smartwatch replace a blood pressure cuff?
Diagnosis CompletedThis study tested how accurately a Samsung Galaxy smartwatch can measure blood pressure over time. Researchers compared the watch's readings to those from a standard medical device used in clinics. The goal was to see if the smartwatch could be a reliable tool for people to monit…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Czech Technical University in Prague • Aim: Diagnosis
Last updated Apr 01, 2026 14:41 UTC
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New blood pressure machine could replace old clinic method
Diagnosis CompletedThis study tested whether a newer, automatic blood pressure machine gives more accurate readings than the traditional clinic method. Researchers compared both methods against a 48-hour wearable monitor (the gold standard) in 149 Chinese adults with high blood pressure. The goal w…
Matched conditions: HYPERTENSION
Sponsor: Chinese University of Hong Kong • Aim: Diagnosis
Last updated Mar 31, 2026 12:12 UTC
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Home blood pressure monitor put to the test
Diagnosis CompletedThis study tested how accurately the Withings BPM Pro 2 home blood pressure monitor measures blood pressure. Researchers compared its readings to those from standard medical devices in 89 adults. The goal was to see if this home device meets international accuracy standards for r…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Withings • Aim: Diagnosis
Last updated Mar 27, 2026 12:38 UTC
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Laser beam could spot hidden heart risk without touch
Diagnosis CompletedThis study tested a new, non-contact laser device to measure artery stiffness, a key sign of heart disease risk, in people with high blood pressure. It compared the new laser method to older, more uncomfortable techniques. The goal was to see if the laser could be a simpler, more…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Diagnosis
Last updated Mar 13, 2026 15:06 UTC
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Breakthrough pill cuts risk of deadly second stroke
Prevention CompletedThis large international trial tested whether a combination of three low-dose blood pressure medicines (a 'Triple Pill') could prevent a second stroke in people who had already survived a serious type of stroke caused by bleeding in the brain. Over 1,600 participants were randoml…
Matched conditions: HYPERTENSION
Phase: PHASE3 • Sponsor: The George Institute • Aim: Prevention
Last updated Mar 30, 2026 14:35 UTC
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Could controlling blood pressure save Kids' bones during cancer treatment?
Prevention CompletedThis study tested whether keeping blood pressure in a tighter, lower range could prevent severe bone damage (osteonecrosis) in children and young adults being treated for a type of blood cancer (acute lymphoblastic leukemia/lymphoma). It compared a more intensive blood pressure c…
Matched conditions: HYPERTENSION
Phase: PHASE2 • Sponsor: St. Jude Children's Research Hospital • Aim: Prevention
Last updated Mar 30, 2026 14:34 UTC
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Could your blood pressure pill also protect your brain?
Prevention CompletedThis study looked back at health records to see if two specific blood pressure drugs (amiloride or triamterene) could help prevent dementia in older adults. Researchers analyzed data from over 155,000 Medicare patients aged 65+ with high blood pressure. The goal was to compare th…
Matched conditions: HYPERTENSION
Sponsor: Brigham and Women's Hospital • Aim: Prevention
Last updated Mar 23, 2026 15:17 UTC
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Barbershops become frontline in fight against high blood pressure
Prevention CompletedThis study tested a program that trains barbershop workers to screen Black men for early signs of high blood pressure, provide lifestyle advice, and help them connect with doctors and community services. It involved 430 men across 20 barbershops to see if this community-based app…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: NYU Langone Health • Aim: Prevention
Last updated Mar 19, 2026 14:55 UTC
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Could your blood pressure pill help shield your memory?
Prevention CompletedThis study looked back at health records to see if certain common blood pressure medications might affect the risk of developing dementia or Alzheimer's disease. It compared two types of drugs in over 160,000 older adults who already had high blood pressure. The goal was to see i…
Matched conditions: HYPERTENSION
Sponsor: Brigham and Women's Hospital • Aim: Prevention
Last updated Mar 09, 2026 14:22 UTC
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Calming VR worlds tested to tame 'White Coat' blood pressure spikes
Symptom relief CompletedThis study tested whether a short, calming virtual reality (VR) experience could help lower blood pressure and reduce anxiety for people at the doctor's office. 79 adults who were already scheduled for a special 24-hour blood pressure test tried a 5-minute VR nature scene during …
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Apr 01, 2026 14:43 UTC
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Ear stimulation tested to calm blood pressure during heart procedures
Symptom relief CompletedThis study tested whether gentle electrical stimulation of a nerve in the ear could help control blood pressure spikes during heart stent procedures. Researchers enrolled 480 adults with high blood pressure who were having coronary stents placed. Participants were randomly assign…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Guozhe Sun • Aim: Symptom relief
Last updated Apr 01, 2026 14:42 UTC
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Doctors test drug combo to stop Surgery's hidden danger
Symptom relief CompletedThis study tested whether two common medications, magnesium and fentanyl, could prevent dangerous spikes in blood pressure and heart rate when a breathing tube is placed during surgery. Researchers enrolled 76 patients aged 50 and older to compare the drugs given alone or togethe…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Ankara City Hospital Bilkent • Aim: Symptom relief
Last updated Mar 31, 2026 12:12 UTC
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Nerve blocks tested as safer alternative for High-Risk amputation patients
Symptom relief CompletedThis study tested whether using targeted nerve blocks with sedation is a safer and more effective way to control pain during leg amputation surgery compared to general anesthesia. It focused on high-risk patients with conditions like diabetes, heart disease, and lung disease. The…
Matched conditions: HYPERTENSION
Phase: PHASE4 • Sponsor: University of Florida • Aim: Symptom relief
Last updated Mar 31, 2026 12:11 UTC
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Can simple breathing and pilates ease the strain of high blood pressure?
Symptom relief CompletedThis study tested whether combining mat Pilates with specific breathing techniques could help people with stage 2 high blood pressure. Researchers compared two different breathing methods to see which one better improved stress, anxiety, fitness, and quality of life. The program …
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: University of Lahore • Aim: Symptom relief
Last updated Mar 27, 2026 12:38 UTC
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Drug showdown: which one better tames Surgery's dangerous stress spike?
Symptom relief CompletedThis study compared two drugs to see which is better at preventing dangerous spikes in heart rate and blood pressure when a breathing tube is placed for surgery. It involved 62 generally healthy adults having elective surgery. Researchers tested a commonly used drug (Lignocain) a…
Matched conditions: HYPERTENSION
Phase: PHASE2, PHASE3 • Sponsor: Shaheed Mohtarma Benazir Bhutto Institue of Trauma • Aim: Symptom relief
Last updated Mar 24, 2026 12:01 UTC
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Can your phone and a fitness tracker help cancer survivors feel better?
Symptom relief CompletedThis study tested a home exercise program for cancer survivors who also have diabetes or high blood pressure. Participants used a wearable device and phone app to track their activity and get feedback while choosing from different exercise options like walking or yoga. The main g…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins • Aim: Symptom relief
Last updated Mar 17, 2026 13:09 UTC
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Medical students test AI tutor for high blood pressure training
Knowledge-focused CompletedThis study tested whether an AI chatbot system could teach medical students about high blood pressure management better than traditional teaching methods. Fifty-two medical students were randomly assigned to learn using either the AI system or standard materials over four weeks. …
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: zhen wang • Aim: Knowledge-focused
Last updated Apr 01, 2026 21:26 UTC
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Scientists hunt for genetic clues to heart disease in syrian patients
Knowledge-focused CompletedThis study aimed to understand if specific gene variations are connected to the risk of developing coronary artery disease and high blood pressure. Researchers analyzed blood samples from 223 Syrian participants, including people with these conditions and healthy individuals. The…
Matched conditions: HYPERTENSION
Sponsor: Damascus University • Aim: Knowledge-focused
Last updated Apr 01, 2026 21:26 UTC
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Can a short class teach patients to dodge a dangerous blood pressure spike?
Knowledge-focused CompletedThis study tested whether a planned education program could improve knowledge about preventing a hypertensive crisis—a dangerous, sudden spike in blood pressure—in people already diagnosed with high blood pressure. Researchers enrolled 35 patients with hypertension and measured t…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Riphah International University • Aim: Knowledge-focused
Last updated Apr 01, 2026 21:25 UTC
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Scientists probe skin stretch to predict heart risks in rare genetic disorder
Knowledge-focused CompletedThis study aimed to understand how skin and blood vessel flexibility are related in people with Williams syndrome, a genetic disorder that can cause heart and blood vessel problems. Researchers measured the stretchiness of skin and arteries in 43 participants, including people wi…
Matched conditions: HYPERTENSION
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:43 UTC
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Researchers probe hidden link between your morning urine and heart health
Knowledge-focused CompletedThis study aimed to understand the relationship between how well the kidneys concentrate urine and the stiffness of major arteries in people with high blood pressure. It involved 72 adults with high blood pressure who were already scheduled for a specialized check-up. Researchers…
Matched conditions: HYPERTENSION
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Clinic tracks young hearts at risk
Knowledge-focused CompletedThis study created a registry to track the long-term heart health of children and young adults who are overweight or obese and have high blood pressure. Researchers collected health information from about 200 participants over time through their regular clinic visits. The goal wa…
Matched conditions: HYPERTENSION
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Could hidden bacteria in your arteries predict a stroke?
Knowledge-focused CompletedThis study aimed to understand if specific bacteria found in the fatty plaques of neck arteries are linked to a higher risk of stroke or other complications after surgery. Researchers observed 200 patients in China who were having surgery to clear a blocked carotid artery. They a…
Matched conditions: HYPERTENSION
Sponsor: Tang-Du Hospital • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Database digs deep to uncover roots of hypertension disparity
Knowledge-focused CompletedThis study analyzed existing health data from 1,692 African Americans with severe high blood pressure. Researchers examined genetic, lifestyle, and social information to understand why this condition is more common and severe in this population. No new treatments were tested; the…
Matched conditions: HYPERTENSION
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Major study seeks roots of heart disease disparities
Knowledge-focused CompletedThis study aimed to understand why African Americans have a higher risk of heart disease. Researchers recruited 670 African American adults to examine how their genes, lifestyle, and social environment (like stress and neighborhood factors) combine to affect heart health. The goa…
Matched conditions: HYPERTENSION
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:40 UTC
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Does knowing your genetic risk for kidney disease help you stay healthier?
Knowledge-focused CompletedThis study aimed to see if telling patients and their doctors about a specific genetic risk for kidney disease would lead to better health management. It involved nearly 6,800 adults of African ancestry with high blood pressure. Researchers tested whether early knowledge of this …
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Wrist watch tracks blood pressure 24/7 in major study
Knowledge-focused CompletedThis study observed how blood pressure changes over 12 weeks in people with high blood pressure. Researchers used a special bracelet that measures blood pressure continuously to see how readings evolve. The study also asked participants about their preferences for different blood…
Matched conditions: HYPERTENSION
Sponsor: Aktiia SA • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:35 UTC
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Scientists hunt for high blood pressure genes in thousands
Knowledge-focused CompletedThis study aimed to understand the genetic causes of high blood pressure. Researchers analyzed previously collected DNA samples from 8,687 participants, focusing on African American, Mexican American, Nigerian, and Jamaican groups. The goal was to identify specific gene variation…
Matched conditions: HYPERTENSION
Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:33 UTC
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Scientists hunt for gut bugs linked to hypertension
Knowledge-focused CompletedThis study looked at whether the types of bacteria living in people's guts are connected to high blood pressure. Researchers compared stool samples from 192 people, including those newly diagnosed with high blood pressure, those whose blood pressure is still high despite medicati…
Matched conditions: HYPERTENSION
Sponsor: Xinjiang Medical University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:29 UTC
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Eye scans reveal if exercise slows brain aging
Knowledge-focused CompletedThis small pilot study explored whether a brief exercise program could improve brain function and blood vessel health in older adults with high blood pressure. Researchers measured changes in fitness, eye blood vessels, thinking skills, and blood markers before and after exercise…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:28 UTC
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Can more sleep lower your nighttime blood pressure?
Knowledge-focused CompletedThis study investigated whether helping adults who sleep less than 7 hours per night to get more sleep could lower their blood pressure during sleep. Researchers compared an 8-week sleep improvement program to a control group. They measured blood pressure over 24 hours and tracke…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Columbia University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:28 UTC
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Could avoiding salt before bedtime lower your nighttime blood pressure?
Knowledge-focused CompletedThis study investigated whether the time of day people eat salt affects their blood pressure and body clock. Researchers tested 53 adults with obesity to see if avoiding high-salt foods before sleep could improve nighttime blood pressure and the body's natural daily rhythms. The …
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC
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New program aims to bridge gap between mental and physical health care
Knowledge-focused CompletedThis pilot study tested a new quality improvement program to help mental health providers better manage heart disease risk factors in their patients. Researchers worked with 85 participants from community mental health organizations to see if the program improved care for conditi…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:07 UTC
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Kidney protein may hold key to Salt's blood pressure impact
Knowledge-focused CompletedThis study aimed to understand how a specific protein made by the kidneys, called uromodulin, influences the relationship between salt in the diet and blood pressure in people with chronic kidney disease. Researchers enrolled 130 adult patients to measure their salt intake, blood…
Matched conditions: HYPERTENSION
Sponsor: Aristotle University Of Thessaloniki • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:18 UTC
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Can a keto drink sharpen your mind and heart health?
Knowledge-focused CompletedThis small, completed study aimed to see if drinking a Keto5 XOGenius beverage daily could improve markers linked to heart and brain health. It involved 6 healthy adults aged 18-50. Researchers measured things like blood pressure, cholesterol, blood vessel function, and cognitive…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: The University of Texas at Arlington • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:18 UTC
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Can better sleep lower your blood pressure overnight?
Knowledge-focused CompletedThis study aimed to understand why people with both high blood pressure and insomnia have a higher risk of heart disease. Researchers gave 149 adults with these conditions a 6-week talk therapy program designed to improve sleep. They then measured changes in nighttime blood press…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:18 UTC
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Scientists probe mystery of high blood pressure in rare disease
Knowledge-focused CompletedThis study aimed to understand why people with a rare genetic disorder called Cytochrome P450 Oxidoreductase (POR) deficiency often develop high blood pressure and blood vessel damage. Researchers compared 51 patients with the condition to healthy individuals, measuring blood pre…
Matched conditions: HYPERTENSION
Sponsor: Ozge Bayrak Demirel • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:16 UTC
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Could your blood pressure pill lower your dementia risk?
Knowledge-focused CompletedThis study looked back at health records to see if certain common blood pressure medications might affect a person's chance of developing dementia or Alzheimer's disease. It compared two groups of drugs in over 800,000 older adults with high blood pressure. The goal was to gather…
Matched conditions: HYPERTENSION
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Mar 19, 2026 14:59 UTC
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Scientists hunt for clues to personalize blood pressure treatment
Knowledge-focused CompletedThis study aimed to find out why some people's blood pressure responds better to certain medications than others. It involved 139 adults with mild to moderate high blood pressure. Researchers tested different drugs and measured factors like diet, body size, and genetics to see wh…
Matched conditions: HYPERTENSION
Phase: PHASE4 • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Mar 19, 2026 14:56 UTC
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Can a pill help close the heart health gap?
Knowledge-focused CompletedThis study aimed to understand why Black Americans have higher rates of high blood pressure and heart disease. Researchers tested if taking a daily antioxidant supplement called MitoQ for 8 weeks could improve blood vessel function and lower blood pressure in middle-aged and olde…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Auburn University • Aim: Knowledge-focused
Last updated Mar 19, 2026 14:56 UTC
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Scientists probe gut for clues to high blood pressure
Knowledge-focused CompletedThis study aimed to understand if there are differences in the gut lining of people with high blood pressure compared to those without it. Researchers analyzed small tissue samples taken during routine colonoscopies from 35 adults. They looked at gene activity and grew mini-gut m…
Matched conditions: HYPERTENSION
Sponsor: University of Florida • Aim: Knowledge-focused
Last updated Mar 18, 2026 14:41 UTC
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Scientists test new combo pill for cholesterol & blood pressure
Knowledge-focused CompletedThis study aimed to understand how the body processes two common heart medications—one for high cholesterol and one for high blood pressure—when taken as separate pills versus as a single combined pill. It involved 52 healthy male volunteers who received the drugs in different se…
Matched conditions: HYPERTENSION
Phase: PHASE1 • Sponsor: JW Pharmaceutical • Aim: Knowledge-focused
Last updated Mar 18, 2026 14:40 UTC
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Scientists probe hidden heart risks of common prostate cancer therapy
Knowledge-focused CompletedThis study aimed to understand why a common prostate cancer treatment (androgen deprivation therapy or ADT) increases the risk of high blood pressure and heart disease. Researchers measured how the nervous system and kidneys control blood pressure in a small group of men before a…
Matched conditions: HYPERTENSION
Phase: PHASE4 • Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated Mar 16, 2026 15:23 UTC
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Scientists test if heavy lifting is safe for hypertensive hearts
Knowledge-focused CompletedThis study aimed to understand how a single session of heavy versus lighter weightlifting affects the heart and blood pressure in people with high blood pressure. Researchers measured participants' heart rate and blood pressure for 24 hours after they performed two different stre…
Matched conditions: HYPERTENSION
Phase: NA • Sponsor: Universidad Católica del Maule • Aim: Knowledge-focused
Last updated Mar 03, 2026 14:06 UTC
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Nausea drug tested as clue to mysterious high blood pressure in diabetes
Knowledge-focused CompletedThis small study aimed to understand if a specific brain chemical pathway contributes to high blood pressure in people with type 2 diabetes. Researchers tested if a drug called aprepitant (normally used for nausea) could change levels of key hormones like aldosterone in five diab…
Matched conditions: HYPERTENSION
Phase: PHASE2 • Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Mar 02, 2026 15:28 UTC