Genetic testing aims to tackle kidney disease racial gap

NCT ID NCT04191824

Completed Knowledge-focused Sponsor: Duke University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether giving African American adults with high blood pressure early access to genetic testing for a kidney disease risk gene (APOL1) could improve their care. Over 6,700 participants were randomly assigned to get their genetic results right away or later. The goal was to see if early knowledge helped lower blood pressure and led to better monitoring of kidney health.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease chronic renal failure syndrome hypertensive disorder kidney disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC KIDNEY DISEASE HYPERTENSION

Contacts and locations

Locations

Baylor Research Institute

Dallas, Texas, 75210, United States
Eskenazi Health

Indianapolis, Indiana, 46202, United States
Icahn School of Medicine at Mount Sinai

New York, New York, 10029, United States
Indiana University

Indianapolis, Indiana, 46202, United States
Meharry Medical College

Nashville, Tennessee, 37208, United States
Nashville General Hospital

Nashville, Tennessee, 37208, United States
Southeastern Healthcare

Lumberton, North Carolina, 28358, United States
The Institute for Family Health

New York, New York, 10035, United States
University Medical Center New Orleans

New Orleans, Louisiana, 70112, United States
University of Alabama at Birmingham

Birmingham, Alabama, 35294, United States
University of Florida - Gainesville

Gainesville, Florida, 32610, United States
University of Florida - Jacksonville

Jacksonville, Florida, 32209, United States
University of Pittsburgh

Pittsburgh, Pennsylvania, 15261, United States
Vanderbilt University Medical Center

Nashville, Tennessee, 37232, United States

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