Groundbreaking study probes genes and environment to explain heart disease in black communities

NCT ID NCT02055209

Completed Knowledge-focused Sponsor: National Heart, Lung, and Blood Institute (NHLBI) Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 16, 2026 · Updated 2 times

Summary

This completed study looked at 670 African American adults to understand how genetics, lifestyle, and social factors like stress and neighborhood affect heart disease risk. Researchers collected blood samples, medical tests, and surveys to find links between ancestry-related DNA variations and conditions like high blood pressure. The goal is to explain why heart disease is more common in this group and to guide future prevention efforts.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could reveal why African Americans have higher rates of heart disease and point to new ways to prevent it.
What could go wrong: This is an observational study, not a treatment trial. It may not directly lead to new therapies, and results may take years to apply.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hypertensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPERTENSION

Contacts and locations

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Locations

National Institutes of Health Clinical Center

Bethesda, Maryland, 20892, United States
Southern Research Group

Jackson, Mississippi, United States

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