Massive study suggests common blood pressure meds may shield brain from dementia

NCT ID NCT05125224

First seen Nov 06, 2025 · Last updated May 16, 2026 · Updated 22 times

Summary

This study looked at medical records from over 163,000 older adults with high blood pressure to see if one type of blood pressure drug (dihydropyridine calcium channel blockers) was linked to a lower risk of developing dementia compared to another (hydrochlorothiazide). The goal was to find if existing medications could be repurposed to help prevent Alzheimer's disease. The study is complete and provides insights, but does not test a new treatment directly.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02120, United States

Conditions

Explore the condition pages connected to this study.