Sound waves zap kidney fat to lower blood pressure

NCT ID NCT06018493

Completed Disease control Sponsor: The First Affiliated Hospital with Nanjing Medical University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed trial tested a new, noninvasive device that uses focused ultrasound to destroy a small amount of fat around the kidney. The goal was to lower blood pressure in people with mild hypertension who were not taking medication. 79 participants were randomly assigned to receive either the real ultrasound or a sham procedure, and their blood pressure was monitored over one to three months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: focused power ultrasound device
What this could lead to: If successful, this could offer a noninvasive, drug-free option to lower blood pressure in people with mild hypertension.
What could go wrong: This is a small, early-stage trial with only 79 participants. The effects may be modest or not last long, and the procedure carries risks like tissue damage or temporary discomfort.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder essential hypertension hypertensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BLOOD PRESSURE CARDIOVASCULAR DISEASES HYPERTENSION

Contacts and locations

Locations

Jiangsu Province Hospital/The Affiliated Hospital of Nanjing Medical University

Nanjing, Jiangsu, 210000, China
Suzhou Municipal Hospital

Suzhou, Jiangsu, 215000, China
The Affiliated Jiangning Hospital of Nanjing Medical University

Nanjing, Jiangsu, 210000, China
The First People's Hospital of Changzhou

Changzhou, Jiangsu, China

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