The First Affiliated Hospital With Nanjing Medical University

This study is testing a multi-step treatment plan for people with locally advanced rectal cancer, aiming to shrink tumors before surgery. It combines a short course of radiation with two immunotherapy drugs (PD-1 antibody and IL-2) and a chemotherapy regimen (CAPOX). The main goa…

This study is for people with stage 3 stomach cancer who have already had surgery to remove their tumor. It aims to see if adding a targeted drug called disitamab vedotin to standard chemotherapy (SOX) is better at preventing the cancer from returning than the standard chemo alon…

This study is testing a new strategy for treating early-stage triple-negative breast cancer, an aggressive type with fewer treatment options. Researchers want to see if using a focused ultrasound (HIFU) to destroy the tumor and an immunotherapy drug (PD-1 inhibitor) to activate t…

This study looks back at the medical records of 25 Chinese patients with limited-stage small cell lung cancer. It aims to see if adding the drug durvalumab after they completed standard chemotherapy and radiation (given one after the other) is safe and helps control the cancer. T…

This early-stage study is testing a new cell therapy called LVIVO-TaVec200 for patients with multiple myeloma that has come back or stopped responding to standard treatments. The study aims to find a safe and effective dose and see how the body handles the treatment. It is for ad…

This study is testing a combination of four treatments for a specific type of advanced esophageal cancer. It aims to see if using a new antibody drug (bemosubaiabimab) together with a cancer growth blocker (anlotinib), radiation, and chemotherapy is safe and effective. The trial …

This early-stage study is testing whether stem cells taken from amniotic fluid can help heal the extremely painful and dangerous skin wounds caused by calciphylaxis, a rare complication of kidney disease. Nine adult patients with calciphylaxis will receive the stem cell treatment…

This study is testing two different drug combinations for people newly diagnosed with marginal zone lymphoma, a type of blood cancer. Researchers want to see which combination works better at controlling the cancer and keeping it from coming back. The trial will involve 169 patie…

This study is testing if adding an immune-boosting drug (thymosin alpha 1) to a standard pre-surgery treatment works better for people with stage III cancer where the stomach meets the esophagus. The standard treatment combines immunotherapy, chemotherapy, and radiation to shrink…

This study is testing whether adding an experimental drug called HRS-4642 to standard chemotherapy can help shrink tumors in people with locally advanced pancreatic cancer that has a specific genetic mutation (KRAS G12D). The goal is to see if this combination makes tumors shrink…

This study is testing whether delivering two drugs directly into the fluid around the brain and spine can help control breast cancer that has spread there. It will involve 26 women with this specific, serious complication. The goal is to see if this targeted approach is safe and …

This study is testing the safety of using robotic surgery to remove a specific type of stomach tumor called a GIST when it's located in a tricky spot. It will enroll 182 patients to see how well the robotic surgery works at removing the tumor completely while preserving nearby he…

This study is testing whether combining precise brain radiation with two cancer drugs (anlotinib and a tubulin inhibitor) can better control breast cancer that has spread to the brain. It is for women with HER2-negative breast cancer who have brain metastases. The main goal is to…

This study is testing whether adding a new drug called linperlisib to an existing three-drug combination helps control non-Hodgkin lymphoma that has come back or hasn't responded to previous treatments. It will involve about 180 adults with specific types of lymphoma to see if th…

This early-stage study is testing whether a treatment made from a patient's own natural killer (NK) immune cells is safe and might help control lung nodules. It is for people who have had some cancerous nodules removed but have others that cannot be operated on again. The main go…

This study is testing a combination of four medications for people newly diagnosed with lymphoma in the brain or spinal cord. The treatment aims to control the cancer and keep it from returning by using immunotherapy plus chemotherapy drugs. Researchers will measure how many pati…

This study is testing a new combination of three drugs (glofitamab, a PD-1 inhibitor, and lenalidomide) for patients with an aggressive type of lymphoma that has come back or not responded to prior treatment and has a specific genetic change called TP53. The main goal is to see i…

This study is testing whether adding an immunotherapy drug called sintilimab to standard chemotherapy (SOX) after surgery helps keep stomach cancer from coming back. It will involve 460 patients with a specific high-risk type of stomach cancer (PD-L1 positive, Stage N3). The main…

This study is testing whether a combination of four existing drugs can help control follicular lymphoma that has returned or stopped responding to previous treatments. It will involve about 33 adults whose cancer has come back after at least two prior therapies. The main goal is …

This study is testing whether a combination of two drugs, tislelizumab and anlotinib, can help control thymoma or thymic carcinoma in patients whose cancer has grown despite initial chemotherapy. It will enroll about 20 adults in China to see if the treatment is safe and effectiv…

This study aims to better predict which pregnant women are at risk for developing gestational diabetes (GDM). It will also test whether a personalized, team-based health plan can help control blood sugar levels during pregnancy and reduce long-term health risks for both mother an…

This study is testing whether two existing cancer drugs work better together for people with advanced HER2-low breast cancer whose disease has worsened despite previous treatment. The trial will enroll 37 patients to receive both disitamab vedotin and bevacizumab, monitoring how …

This study is testing a new way to treat melasma, a common skin condition that causes brown patches on the face. Researchers are using gentle ultrasound waves to help a special skin-lightening solution absorb better into the skin. They will compare the treated side of the face to…

This study is testing if adding a drug called venetoclax for one year to a patient's current BTK inhibitor therapy can lead to a deep remission in Chronic Lymphocytic Leukemia (CLL). The goal is to see if patients can then safely stop all treatment. The study will enroll 79 adult…

This study is testing if a new combination of immunotherapy drugs (tislelizumab and interleukin-2) plus standard chemotherapy works better than chemotherapy alone when given before surgery for locally advanced rectal cancer. The goal is to see if this approach shrinks tumors more…

This study is testing a new artificial intelligence (AI) system designed to help doctors more accurately detect and determine the stage of stomach cancer from standard CT scans. It will involve 8,000 patients with confirmed stomach cancer who are scheduled for surgery. The main g…

This study is testing a new type of heart MRI scan that uses an iron-based agent (ferumoxytol) to see if it can detect hardened, calcified arteries as well as or better than the current standard CT scan. It will enroll 100 patients who already have confirmed artery calcification …

This study is testing whether a personalized sound therapy can reduce the perception of ringing in the ears (tinnitus) for people who have had it for over six months. Researchers will create custom sound patterns based on each participant's hearing and tinnitus characteristics, a…

This study is testing a new way to measure disease activity in people with axial spondyloarthritis (axSpA), a type of chronic spinal arthritis. Researchers will use whole-body MRI scans and computer analysis to create a more accurate model for tracking inflammation and damage. Th…