New hope for brain lymphoma patients with targeted drug cocktail

NCT ID NCT07410520

First seen Feb 14, 2026 · Last updated May 14, 2026 · Updated 12 times

Summary

This study tests a combination of four drugs (PD-1 inhibitor, rituximab, methotrexate, and orelabrutinib) in 50 adults with newly diagnosed or relapsed central nervous system lymphoma. The goal is to see if this treatment can stop the cancer from growing for at least one year. Participants will receive the drugs intravenously and by mouth, and their progress will be monitored with MRI scans and follow-up visits.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The First Affiliated Hospital with Nanjing Medical University

    RECRUITING

    Nanjing, Jiangsu, 210029, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.