Can a cancer drug stop brain lymphoma from coming back?

NCT ID NCT04401774

First seen Jan 08, 2026 · Last updated May 21, 2026 · Updated 23 times

Summary

This study tested the drug nivolumab in people with primary central nervous system lymphoma (PCNSL) whose spinal fluid still showed signs of tumor DNA after their first round of chemotherapy. The goal was to see if nivolumab could safely prevent the cancer from returning. Fourteen participants received the drug as a maintenance treatment, and researchers tracked side effects and whether the tumor DNA became undetectable after one year.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)

    Basking Ridge, New Jersey, 07920, United States

  • Memorial Sloan Kettering Bergen (Limited Protocol Activities)

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center (All Protocol Activities)

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Commack (Limited Protocol Activities)

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Monmouth (Limited Protocol Activities)

    Middletown, New Jersey, 07748, United States

  • Memorial Sloan Kettering Nassau (Limited protocol activities)

    Uniondale, New York, 11553, United States

  • Memorial Sloan Kettering Westchester (Limited Protocol Activities)

    Harrison, New York, 10604, United States

Conditions

Explore the condition pages connected to this study.