New combo attack on aggressive breast cancer shows promise in early trial

NCT ID NCT07394387

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether using focused ultrasound (HIFU) to destroy tumors, with or without an immune-boosting drug (PD-1 inhibitor), before standard chemotherapy can improve outcomes for people with early-stage triple-negative breast cancer. About 58 participants will receive one of two treatment sequences, then undergo surgery. The main goal is to see if the cancer is completely gone at the time of surgery.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The First Affiliated Hospital with Nanjing Medical University

    RECRUITING

    Nanjing, Jiangsu, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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