Can your own immune cells fight lung nodules?

NCT ID NCT07185035

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early study tests whether a patient's own natural killer (NK) cells, given as infusions, are safe and can help shrink lung nodules. 24 adults with high-risk nodules will receive multiple doses. The main goal is to check for side effects within 28 days, with tumor response as a secondary measure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
autologous NK cells (KN5001)
What this could lead to
If it works, this could point toward a new way to shrink or control lung nodules without surgery.
What could go wrong
This is a very early, small trial (24 people) focused on safety. It may not show clear benefit, and side effects are unknown.

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Conditions

The condition(s) this trial relates to.

Multiple Pulmonary Nodules pulmonary coin lesion

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The First Affiliated Hospital with Nanjing Medical University

    RECRUITING

    Nanjing, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.