Pulmonary coin lesion

This early study tests whether a patient's own natural killer (NK) cells, given as infusions, are safe and can help shrink lung nodules. 24 adults with high-risk nodules will receive multiple doses. The main goal is to check for side effects within 28 days, with tumor response as…

This study is testing a blood test that looks for tumor DNA to see if it can more accurately tell whether a lung nodule found on a CT scan is cancer. About 590 people getting lung cancer screening will give blood samples and be followed for 3 years. The goal is to improve how we …

The NIMBLE study is testing whether blood-based biomarkers can accurately distinguish between cancerous and non-cancerous lung nodules. Researchers will analyze blood samples from 1,800 patients referred with a lung nodule, looking at protein markers, epigenetic smoking markers, …

This study tests an FDA-approved AI software that analyzes CT scans of lung nodules to estimate cancer risk. 300 adults aged 35-89 with newly found lung nodules will be randomly assigned to have their doctors use the AI tool or not. The goal is to see if the AI helps doctors mana…

This observational study is testing whether a breath test can accurately tell the difference between benign and malignant lung nodules. Researchers will analyze volatile organic compounds (VOCs) in the exhaled breath of 3,000 people with lung nodules. The goal is to develop an AI…

This study enrolls 25 smokers who have a suspicious lung nodule and need a biopsy or bronchoscopy. At their first visit, doctors strongly advise quitting and offer support like counseling and a free program. The study tracks how many patients successfully quit over 3 months, usin…